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Surgery Today
Published in: Surgery Today 2/2017

01-02-2017 | Original Article

Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection

Authors: Tadashi Yoshida, Shigenori Homma, Susumu Shibasaki, Tatsushi Shimokuni, Hideyasu Sakihama, Norihiko Takahashi, Hideki Kawamura, Akinobu Taketomi

Published in: Surgery Today | Issue 2/2017

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Abstract

Purpose

Effective postoperative analgesia is essential to a patient’s recovery after laparoscopic colon resection (LCR). We introduce a new analgesic protocol using fentanyl plus celecoxib following LCR.

Methods

The subjects of this retrospective comparative study were 137 patients who underwent LCR, 63 of whom were treated with 72 h of epidural anesthesia (group E), and 74 of whom were treated with 24 h of fentanyl intravenous injection followed by 7 days of oral celecoxib (group FC). We evaluated the safety and efficacy of this new protocol.

Results

The combination of fentanyl and celecoxib maintained a low postoperative pain score (<1.5, evaluated by the FACES Pain Scale) and reduced the need for rescue analgesic drugs for 7 days (groups E vs. FC: 5.39 ± 3.77 vs. 2.79 ± 2.92, p < 0.001). The postoperative hospital stay was almost equal for the two groups (E vs. FC: 11.1 ± 4.5 vs. 10.3 ± 4.8 days, p = 0.315). The operating room stay other than for surgery was significantly shorter for group FC (E vs. FC: 128.7 ± 30.5 vs. 107.2 ± 17.0 min, p < 0.001). Neither group experienced complications, apart from one group FC patient, who suffered transient nausea and vertigo.

Conclusions

The new analgesic protocol using fentanyl plus celecoxib is an effective and time-saving strategy for LCR.
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Metadata
Title
Postoperative analgesia using fentanyl plus celecoxib versus epidural anesthesia after laparoscopic colon resection
Authors
Tadashi Yoshida
Shigenori Homma
Susumu Shibasaki
Tatsushi Shimokuni
Hideyasu Sakihama
Norihiko Takahashi
Hideki Kawamura
Akinobu Taketomi
Publication date
01-02-2017
Publisher
Springer Japan
Published in
Surgery Today / Issue 2/2017
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-016-1356-y

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