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Surgery Today
Published in: Surgery Today 1/2017

01-01-2017 | Original Article

Outcomes of lung cancer surgery in patients with coronary artery disease: a decade of experience at a single institution

Authors: Ryu Kanzaki, Masayoshi Inoue, Masato Minami, Yasushi Shintani, Soichiro Funaki, Tomohiro Kawamura, Meinoshin Okumura

Published in: Surgery Today | Issue 1/2017

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Abstract

Purpose

The aim of this study is to investigate the surgical outcomes of surgery for non-small cell lung cancer (NSCLC) in patients with coronary artery disease (CAD).

Methods

Among 805 patients who underwent surgery for NSCLC at our hospital within a recent 10-year period, 43 (5.3 %) had a history of CAD. We analyzed the surgical outcomes and risk factors for postoperative complications in these 43 patients.

Results

The postoperative mortality and morbidity rates were 2 and 42 %, respectively. The morbidity rate was significantly higher in the patients with CAD than in those without CAD (P < 0.01). Postoperative cerebrovascular or cardiovascular events occurred in four patients (9 %). Having two of the following was significantly associated with the development of postoperative complications: decreased cardiac function, respiratory dysfunction, or deteriorated renal function (p = 0.04). The 5-year overall and disease-free survival rates of the patients with CAD were 75.6 and 64.5 %, respectively; comparable with those of the patients without CAD; at 77.9 % and 72.5 %, respectively (p = 0.46 and 0.69).

Conclusions

Patients with NSCLC and a history of CAD are at higher risk of complications after pulmonary resection. Combined decreased organ function is a risk factor for postoperative complications. CAD did not influence the long-term outcomes of patients after pulmonary resection for NSCLC.
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Metadata
Title
Outcomes of lung cancer surgery in patients with coronary artery disease: a decade of experience at a single institution
Authors
Ryu Kanzaki
Masayoshi Inoue
Masato Minami
Yasushi Shintani
Soichiro Funaki
Tomohiro Kawamura
Meinoshin Okumura
Publication date
01-01-2017
Publisher
Springer Japan
Published in
Surgery Today / Issue 1/2017
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-016-1355-z

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