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Surgery Today
Published in: Surgery Today 8/2016

01-08-2016 | Review Article

Current surgical strategies for malignant pleural mesothelioma

Authors: Teruhisa Takuwa, Seiki Hasegawa

Published in: Surgery Today | Issue 8/2016

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Abstract

Malignant pleural mesothelioma (MPM) is associated with a poor prognosis. The main components of multimodality treatment include surgery, chemotherapy, and radiation therapy. Surgery remains controversial. Two procedures are currently offered: extrapleural pneumonectomy (EPP) and pleurectomy/decortication (P/D). The recent scientific literature suggests that P/D is a well-tolerated procedure, with the potential of becoming a default procedure in multimodality regimens. However, the precise treatment schemes and surgical procedures are yet to be established. In our study, we review the advantages and disadvantages of EPP and P/D, summarize the post-EPP and post-P/D observations (including mortality, morbidity, and median survival time), and discuss the choice of surgical technique (EPP vs. P/D). Moreover, we highlight the aspects of the multimodality treatments that are offered to MPM patients, including chemotherapy, radiotherapy, intensity-modulated radiation therapy, and other types of therapy.
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Metadata
Title
Current surgical strategies for malignant pleural mesothelioma
Authors
Teruhisa Takuwa
Seiki Hasegawa
Publication date
01-08-2016
Publisher
Springer Japan
Published in
Surgery Today / Issue 8/2016
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-015-1275-3

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