Skip to main content
Top
Published in: Surgery Today 11/2014

01-11-2014 | Original Article

The early and mid-term results of mitral valve repair for mitral regurgitation in children

Authors: Zhaolei Jiang, Ju Mei, Fangbao Ding, Chunrong Bao, Jiaquan Zhu, Min Tang, Nan Ma, Jianbing Huang, Saie Shen

Published in: Surgery Today | Issue 11/2014

Login to get access

Abstract

Purpose

To review the surgical techniques and mid-term results of mitral valve repair in children with moderate or severe mitral regurgitation (MR).

Methods

One hundred and seven children with moderate or severe MR, aged 19.6 ± 8.5 months, were enrolled in this study. The surgical techniques used for mitral valve repair varied according to the mitral valve morphology, and included annuloplasty, annuloplasty ring, cleft closure, reconstruction of the posterior leaflet, etc. The concomitant cardiac anomalies were treated simultaneously. The results of repair were evaluated by transesophageal echocardiography performed during the operation and by serial transthoracic echocardiography performed during the follow-up.

Results

One hundred and six cases had no more than mild regurgitation intraoperatively, whereas only one case had moderate regurgitation. This patient underwent redo repair immediately, and the subsequent regurgitation was trivial. The in-hospital mortality rate was 0.9 % (1/107). The average follow-up was 46.5 ± 8.2 months. One patient died of heart failure 10 months postoperatively. The freedom from moderate or severe regurgitation after mitral valve repair was 92.3 ± 3.3 %.

Conclusion

Pediatric patients with moderate or severe MR require early surgical treatment. The early and mid-term results of mitral valve repair in pediatric patients were satisfactory.
Literature
1.
go back to reference Cohn LH. Mitral valve repair. Mastery of cardiothoracic surgery. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins Inc; 2007. p. 341–52. Cohn LH. Mitral valve repair. Mastery of cardiothoracic surgery. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins Inc; 2007. p. 341–52.
2.
go back to reference Rochae Silva A, Herdy GV, Vieira AA, Simões LC. Surgical mitral valve repair in children with rheumatic fever. Arq Bras Cardiol. 2009;92(6):400–4 (417–21, 433–8). Rochae Silva A, Herdy GV, Vieira AA, Simões LC. Surgical mitral valve repair in children with rheumatic fever. Arq Bras Cardiol. 2009;92(6):400–4 (417–21, 433–8).
3.
go back to reference Pedrazzini GB, Faletra F, Vassalli G, Demertzis S, Moccetti T. Mitral regurgitation. Swiss Med Wkly. 2010;140(3–4):36–43.PubMed Pedrazzini GB, Faletra F, Vassalli G, Demertzis S, Moccetti T. Mitral regurgitation. Swiss Med Wkly. 2010;140(3–4):36–43.PubMed
4.
go back to reference Brizard C. Mitral valve repair in children. Mastery of cardiothoracic surgery. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins Inc; 2007. p. 1008–16. Brizard C. Mitral valve repair in children. Mastery of cardiothoracic surgery. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins Inc; 2007. p. 1008–16.
5.
go back to reference Carpentier A, Branchini B, Cour JC, Asfaou E, Villani M, Deloche A, et al. Congenital malformations of the mitral valve in children. Pathology and surgical treatment. J Thorac Cardiovasc Surg. 1976;72:854–66.PubMed Carpentier A, Branchini B, Cour JC, Asfaou E, Villani M, Deloche A, et al. Congenital malformations of the mitral valve in children. Pathology and surgical treatment. J Thorac Cardiovasc Surg. 1976;72:854–66.PubMed
6.
go back to reference Chauvaud S, Fuzellier JF, Houel R, Berrebi A, Mihaileanu S, Carpentier A. Reconstructive surgery in congenital mitral valve insufficiency (Carpentier’s techniques): long-term results. J Thorac Cardiovasc Surg. 1998;115:84–92 (discussion 92–93).PubMedCrossRef Chauvaud S, Fuzellier JF, Houel R, Berrebi A, Mihaileanu S, Carpentier A. Reconstructive surgery in congenital mitral valve insufficiency (Carpentier’s techniques): long-term results. J Thorac Cardiovasc Surg. 1998;115:84–92 (discussion 92–93).PubMedCrossRef
7.
go back to reference Minich LL, Atz AM, Colan SD, Sleeper LA, Mital S, Jaggers J, et al. Partial and transitional atrioventricular septal defect outcomes. Ann Thorac Surg. 2010;89(2):530–6.PubMedCrossRefPubMedCentral Minich LL, Atz AM, Colan SD, Sleeper LA, Mital S, Jaggers J, et al. Partial and transitional atrioventricular septal defect outcomes. Ann Thorac Surg. 2010;89(2):530–6.PubMedCrossRefPubMedCentral
8.
go back to reference Wood AE, Healy DG, Nolke L, Duff D, Oslizlok P, Walsh K. Mitral valve reconstruction in a pediatric population: late clinical results and predictors of long-term outcome. J Thorac Cardiovasc Surg. 2005;130(1):66–73.PubMedCrossRef Wood AE, Healy DG, Nolke L, Duff D, Oslizlok P, Walsh K. Mitral valve reconstruction in a pediatric population: late clinical results and predictors of long-term outcome. J Thorac Cardiovasc Surg. 2005;130(1):66–73.PubMedCrossRef
9.
go back to reference Shuhaiber J, Anderson RJ. Meta-analysis of clinical outcomes following surgical mitral valve repair or replacement. Eur J Cardiothorac Surg. 2007;31:267–75.PubMedCrossRef Shuhaiber J, Anderson RJ. Meta-analysis of clinical outcomes following surgical mitral valve repair or replacement. Eur J Cardiothorac Surg. 2007;31:267–75.PubMedCrossRef
10.
go back to reference Beierlein W, Becker V, Yates R, Tsang V, Elliott M, de Leval M, et al. Long-term follow-up after mitral valve replacement in childhood: poor event-free survival in the young child. Eur J Cardiothorac Surg. 2007;31(5):860–5.PubMedCrossRef Beierlein W, Becker V, Yates R, Tsang V, Elliott M, de Leval M, et al. Long-term follow-up after mitral valve replacement in childhood: poor event-free survival in the young child. Eur J Cardiothorac Surg. 2007;31(5):860–5.PubMedCrossRef
11.
go back to reference Tesler UF, Cerin G, Novelli E, Popa A, Diena M. Evolution of surgical techniques for mitral valve repair. Tex Heart Inst J. 2009;36(5):438–40.PubMedPubMedCentral Tesler UF, Cerin G, Novelli E, Popa A, Diena M. Evolution of surgical techniques for mitral valve repair. Tex Heart Inst J. 2009;36(5):438–40.PubMedPubMedCentral
12.
go back to reference Curi–Curi P, Ramírez-Marroquín S, Cervantes-Salazar J, Soulé M, Erdmenger J, Calderón-Colmenero J. Surgical repair of congenital mitral valve malformations. Arch Cardiol Mex. 2010;80(2):87–94.PubMed Curi–Curi P, Ramírez-Marroquín S, Cervantes-Salazar J, Soulé M, Erdmenger J, Calderón-Colmenero J. Surgical repair of congenital mitral valve malformations. Arch Cardiol Mex. 2010;80(2):87–94.PubMed
13.
go back to reference Zias EA, Mavroudis C, Backer CL, Kohr LM, Gotteiner NL, Rocchini AP. Surgical repair of the congenitally malformed mitral valve in infants and children. Ann Thorac Surg. 1998;66(5):1551–9.PubMedCrossRef Zias EA, Mavroudis C, Backer CL, Kohr LM, Gotteiner NL, Rocchini AP. Surgical repair of the congenitally malformed mitral valve in infants and children. Ann Thorac Surg. 1998;66(5):1551–9.PubMedCrossRef
14.
go back to reference Oppido G, Davies B, McMullan DM, Cochrane AD, Cheung MM, d’Udekem Y, et al. Surgical treatment of congenital mitral valve disease: midterm results of a repair-oriented policy. J Thorac Cardiovasc Surg. 2008;135:1313–21.PubMedCrossRef Oppido G, Davies B, McMullan DM, Cochrane AD, Cheung MM, d’Udekem Y, et al. Surgical treatment of congenital mitral valve disease: midterm results of a repair-oriented policy. J Thorac Cardiovasc Surg. 2008;135:1313–21.PubMedCrossRef
15.
go back to reference Stellin G, Padalino MA, Vida VL, Boccuzzo G, Orrù E, Biffanti R, et al. Surgical repair of congenital mitral valve malformations in infancy and childhood: a single-center 36-year experience. J Thorac Cardiovasc Surg. 2010;140(6):1238–44.PubMedCrossRef Stellin G, Padalino MA, Vida VL, Boccuzzo G, Orrù E, Biffanti R, et al. Surgical repair of congenital mitral valve malformations in infancy and childhood: a single-center 36-year experience. J Thorac Cardiovasc Surg. 2010;140(6):1238–44.PubMedCrossRef
16.
go back to reference Hetzer R, Delmo Walter EB, Hübler M, Alexi-Meskishvili V, Weng Y, Nagdyman N, et al. Modified surgical techniques and long-term outcome of mitral valve reconstruction in 111 children. Ann Thorac Surg. 2008;86(2):604–13.PubMedCrossRef Hetzer R, Delmo Walter EB, Hübler M, Alexi-Meskishvili V, Weng Y, Nagdyman N, et al. Modified surgical techniques and long-term outcome of mitral valve reconstruction in 111 children. Ann Thorac Surg. 2008;86(2):604–13.PubMedCrossRef
17.
go back to reference Sheikh KH, Bengtson JR, Rankin JS, de Bruijn NP, Kisslo J. Intraoperative transesophageal Doppler color flow imaging used to guide patient selection and operative treatment of ischemic mitral regurgitation. Circulation. 1991;84:594–604.PubMedCrossRef Sheikh KH, Bengtson JR, Rankin JS, de Bruijn NP, Kisslo J. Intraoperative transesophageal Doppler color flow imaging used to guide patient selection and operative treatment of ischemic mitral regurgitation. Circulation. 1991;84:594–604.PubMedCrossRef
18.
go back to reference Mahadin DR, Srivastava S, Parness IA, Nguyen K, Love BA, Walsh R, et al. Outcomes of mitral regurgitation associated with large ventricular septal defect and a normal mitral valve apparatus: does intact atrial septum have an impact? Pediatr Cardiol. 2011;32(8):1128–31.PubMedCrossRef Mahadin DR, Srivastava S, Parness IA, Nguyen K, Love BA, Walsh R, et al. Outcomes of mitral regurgitation associated with large ventricular septal defect and a normal mitral valve apparatus: does intact atrial septum have an impact? Pediatr Cardiol. 2011;32(8):1128–31.PubMedCrossRef
19.
go back to reference Gunther T, Mazzitelli D, Schreiber C. Mitral valve replacement in children under 6 years of age. Eur J Cardio Thorac Surg. 2000;17(4):426–30.CrossRef Gunther T, Mazzitelli D, Schreiber C. Mitral valve replacement in children under 6 years of age. Eur J Cardio Thorac Surg. 2000;17(4):426–30.CrossRef
20.
go back to reference Hisatomi K, Isomura T, Sato T, Kosuga K, Ohishi K, Katoh H. Mitral valve repair for mitral regurgitation with ventricular septal defect in children. Ann Thorac Surg. 1996;62(6):1773–7.PubMedCrossRef Hisatomi K, Isomura T, Sato T, Kosuga K, Ohishi K, Katoh H. Mitral valve repair for mitral regurgitation with ventricular septal defect in children. Ann Thorac Surg. 1996;62(6):1773–7.PubMedCrossRef
21.
go back to reference Berrebi A. Mitral valve repair: echocardiography is its best friend. Rev Esp Cardiol. 2011;64(7):554–6.CrossRef Berrebi A. Mitral valve repair: echocardiography is its best friend. Rev Esp Cardiol. 2011;64(7):554–6.CrossRef
22.
go back to reference Sakaguchi T, Nishi H, Miyagawa S, Yoshikawa Y, Fukushima S, Yoshioka D, et al. One-knot technique: a simple modification of the loop technique for mitral valve repair. Surg Today. 2013;43(6):705–7.PubMedCrossRef Sakaguchi T, Nishi H, Miyagawa S, Yoshikawa Y, Fukushima S, Yoshioka D, et al. One-knot technique: a simple modification of the loop technique for mitral valve repair. Surg Today. 2013;43(6):705–7.PubMedCrossRef
23.
go back to reference Aharon AS, Laks H, Drinkwater DC, Chugh R, Gates RN, Grant PW, et al. Early and late results of mitral valve repair in children. J Thorac Cardiovasc Surg. 1994;107:1262–71.PubMed Aharon AS, Laks H, Drinkwater DC, Chugh R, Gates RN, Grant PW, et al. Early and late results of mitral valve repair in children. J Thorac Cardiovasc Surg. 1994;107:1262–71.PubMed
24.
go back to reference Delmo Walter EM, Hetzer R. Mitral valve repair in children. Mitral Valve Repair, II. Darmstadt, Germany: Steinkopff; 2011. p. 41–56. Delmo Walter EM, Hetzer R. Mitral valve repair in children. Mitral Valve Repair, II. Darmstadt, Germany: Steinkopff; 2011. p. 41–56.
Metadata
Title
The early and mid-term results of mitral valve repair for mitral regurgitation in children
Authors
Zhaolei Jiang
Ju Mei
Fangbao Ding
Chunrong Bao
Jiaquan Zhu
Min Tang
Nan Ma
Jianbing Huang
Saie Shen
Publication date
01-11-2014
Publisher
Springer Japan
Published in
Surgery Today / Issue 11/2014
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-013-0816-x

Other articles of this Issue 11/2014

Surgery Today 11/2014 Go to the issue