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Acta Diabetologica
Published in: Acta Diabetologica 5/2016

01-10-2016 | Original Article

The influence of type 2 diabetes and arterial hypertension on right ventricular layer-specific mechanics

Authors: Marijana Tadic, Cesare Cuspidi, Vladan Vukomanovic, Sanja Ilic, Vera Celic, Philippe Obert, Vesna Kocijancic

Published in: Acta Diabetologica | Issue 5/2016

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Abstract

Aims

The aim of the investigation was to evaluate layer-specific right ventricular (RV) deformation in normotensive and hypertensive subjects with type 2 diabetes mellitus (DM).

Methods

This cross-sectional study included 129 subjects (40 controls, 42 normotensive DM and 47 hypertensive DM patients) who underwent complete two-dimensional echocardiographic examination (2DE) including multilayer strain analysis.

Results

2DE RV global and free wall longitudinal strains were reduced in normotensive and hypertensive DM subjects than in controls. RV global longitudinal layer-specific strains (endo-, mid- and epicardial) were lower in normotensive and hypertensive DM patients than in controls. On the other side, layer-specific strains of RV free wall were lower in hypertensive DM patients than in controls, without significant difference between controls and normotensive DM subjects. Parameters of DM control (fasting glucose and glycosylated hemoglobin) were associated with 2DE RV global longitudinal endo- and mid-myocardial layer strain.

Conclusions

Diabetes and hypertension significantly influence RV mechanics assessed by 2DE conventional and 2DE multilayer strain. Hypertension has an additive unfavorable influence on RV deformation in diabetic patients. Laboratory parameters of diabetic control were associated with RV structure, diastolic function and mechanics assessed with complex 2DE strain analysis.
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Metadata
Title
The influence of type 2 diabetes and arterial hypertension on right ventricular layer-specific mechanics
Authors
Marijana Tadic
Cesare Cuspidi
Vladan Vukomanovic
Sanja Ilic
Vera Celic
Philippe Obert
Vesna Kocijancic
Publication date
01-10-2016
Publisher
Springer Milan
Published in
Acta Diabetologica / Issue 5/2016
Print ISSN: 0940-5429
Electronic ISSN: 1432-5233
DOI
https://doi.org/10.1007/s00592-016-0874-9

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