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Published in: European Journal of Orthopaedic Surgery & Traumatology 8/2016

01-12-2016 | Original Article • KNEE - ARTHROPLASTY

Knee arthrodesis with a long intramedullary nail as limb salvage for complex periprosthetic infections

Authors: Nima Razii, Ammar M. I. Abbas, Rahul Kakar, Sanjeev Agarwal, Rhidian Morgan-Jones

Published in: European Journal of Orthopaedic Surgery & Traumatology | Issue 8/2016

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Abstract

Background

Periprosthetic infection following total knee arthroplasty is a devastating complication, which is not always satisfactorily resolved by revision surgery. Arthrodesis is a salvage alternative to above-knee amputation or permanent resection arthroplasty. Fixation options include internal compression plating, external fixation, and intramedullary nails.

Methods

We retrospectively reviewed twelve consecutive cases (9 males, 3 females; mean age, 67 years) of knee arthrodesis with a long intramedullary nail, performed at a single institution between 2003 and 2014. Desired outcomes were the ability to mobilize without pain, solid radiographic fusion, and the eradication of infection.

Results

Mean follow-up was 48.5 months (range, 9–120 months). Eleven patients (92 %) demonstrated stable fusion, ten patients (83 %) were ambulatory without pain, and ten patients (83 %) remained without infection at most recent follow-up. Eight patients (67 %) achieved union at an average of 12 months; three required repeat procedures, achieving union at an average of 9 months. There was a significant difference (P < 0.01) between the numbers of previous operations amongst the eight patients who initially achieved union (mean, 3.25) and three who subsequently required repeat procedures (mean, 8.33).

Conclusions

In contrast to similar studies, we performed a single-stage exchange where possible, while comparable ambulatory and fusion rates were observed. Numerous previous attempts at revision arthroplasty, co-morbidities, and infections with highly resistant organisms have been associated with further complications. Although technically challenging, knee arthrodesis with a long intramedullary nail offers an acceptable limb salvage procedure for carefully selected patients with complex periprosthetic infections.
Literature
1.
go back to reference Bozic KJ, Durbhakula S, Berry DJ, Naessens JM, Rappaport K, Cisternas M et al (2005) Differences in patient and procedure characteristics and hospital resource use in primary and revision total joint arthroplasty: a multicenter study. J Arthroplasty 20(7 Suppl 3):17–25CrossRefPubMed Bozic KJ, Durbhakula S, Berry DJ, Naessens JM, Rappaport K, Cisternas M et al (2005) Differences in patient and procedure characteristics and hospital resource use in primary and revision total joint arthroplasty: a multicenter study. J Arthroplasty 20(7 Suppl 3):17–25CrossRefPubMed
2.
go back to reference Christie MJ, DeBoer DK, McQueen DA, Cooke FW, Hahn DL (2003) Salvage procedures for failed total knee arthroplasty. J Bone Joint Surg Am 85-A(Suppl. 1):S58–S62CrossRef Christie MJ, DeBoer DK, McQueen DA, Cooke FW, Hahn DL (2003) Salvage procedures for failed total knee arthroplasty. J Bone Joint Surg Am 85-A(Suppl. 1):S58–S62CrossRef
3.
go back to reference Key JA (1932) Positive pressure in arthrodesis for tuberculosis of the knee joint. South Med J 25:909–915CrossRef Key JA (1932) Positive pressure in arthrodesis for tuberculosis of the knee joint. South Med J 25:909–915CrossRef
4.
go back to reference Charnley J, Lowe HG (1958) A study of the end-results of compression arthrodesis of the knee. J Bone Joint Surg Br 40-B(4):633–635PubMed Charnley J, Lowe HG (1958) A study of the end-results of compression arthrodesis of the knee. J Bone Joint Surg Br 40-B(4):633–635PubMed
5.
go back to reference Isiklar ZU, Landon GC, Tullos HS (1994) Amputation after failed total knee arthroplasty. Clin Orthop Relat Res 299:173–178 Isiklar ZU, Landon GC, Tullos HS (1994) Amputation after failed total knee arthroplasty. Clin Orthop Relat Res 299:173–178
6.
go back to reference Chen AF, Kinback NC, Heyl AE, McClain EJ, Klatt BA (2012) Better function for fusions versus above-the-knee amputations for recurrent periprosthetic knee infection. Clin Orthop Relat Res 470:2737–2745CrossRefPubMedPubMedCentral Chen AF, Kinback NC, Heyl AE, McClain EJ, Klatt BA (2012) Better function for fusions versus above-the-knee amputations for recurrent periprosthetic knee infection. Clin Orthop Relat Res 470:2737–2745CrossRefPubMedPubMedCentral
7.
go back to reference Damron TA, McBeath AA (1995) Arthrodesis following failed total knee arthroplasty: comprehensive review and meta-analysis of recent literature. Orthopedics 18(4):361–368PubMed Damron TA, McBeath AA (1995) Arthrodesis following failed total knee arthroplasty: comprehensive review and meta-analysis of recent literature. Orthopedics 18(4):361–368PubMed
8.
go back to reference Somayaji HS, Tsaggerides P, Ware HE, Dowd GS (2008) Knee arthrodesis—a review. Knee 15(4):247–254CrossRefPubMed Somayaji HS, Tsaggerides P, Ware HE, Dowd GS (2008) Knee arthrodesis—a review. Knee 15(4):247–254CrossRefPubMed
9.
go back to reference Oostenbroek HJ, van Roermund PM (2001) Arthrodesis of the knee after an infected arthroplasty using the Ilizarov method. J Bone Joint Surg Br 83(1):50–54CrossRefPubMed Oostenbroek HJ, van Roermund PM (2001) Arthrodesis of the knee after an infected arthroplasty using the Ilizarov method. J Bone Joint Surg Br 83(1):50–54CrossRefPubMed
10.
go back to reference Pritchett JW, Mallin BA, Matthews AC (1988) Knee arthrodesis with a tension-band plate. J Bone Joint Surg Am 70(2):285–288CrossRefPubMed Pritchett JW, Mallin BA, Matthews AC (1988) Knee arthrodesis with a tension-band plate. J Bone Joint Surg Am 70(2):285–288CrossRefPubMed
11.
go back to reference Kuo AC, Meehan JP, Lee M (2005) Knee fusion using dual platings with the locking compression plate. J Arthroplasty 20(6):772–776CrossRefPubMed Kuo AC, Meehan JP, Lee M (2005) Knee fusion using dual platings with the locking compression plate. J Arthroplasty 20(6):772–776CrossRefPubMed
12.
go back to reference Van Rensch PJ, Van de Pol GJ, Goosen JH, Wymenga AB, De Man FH (2014) Arthrodesis of the knee following failed arthroplasty. Knee Surg Sports Traumatol Arthrosc 22(8):1940–1948CrossRefPubMed Van Rensch PJ, Van de Pol GJ, Goosen JH, Wymenga AB, De Man FH (2014) Arthrodesis of the knee following failed arthroplasty. Knee Surg Sports Traumatol Arthrosc 22(8):1940–1948CrossRefPubMed
13.
go back to reference Yeoh D, Goddard R, Macnamara P, Bowman N, Miles K, East D et al (2008) A comparison of two techniques for knee arthrodesis: the custom made intramedullary Mayday nail versus a monoaxial external fixator. Knee 15(4):263–267CrossRefPubMed Yeoh D, Goddard R, Macnamara P, Bowman N, Miles K, East D et al (2008) A comparison of two techniques for knee arthrodesis: the custom made intramedullary Mayday nail versus a monoaxial external fixator. Knee 15(4):263–267CrossRefPubMed
14.
go back to reference Schwarzkopf R, Kahn TL, Succar J, Ready JE (2014) Success of different knee arthrodesis techniques after failed total knee arthroplasty: is there a preferred technique? J Arthroplasty 29(5):982–988CrossRefPubMed Schwarzkopf R, Kahn TL, Succar J, Ready JE (2014) Success of different knee arthrodesis techniques after failed total knee arthroplasty: is there a preferred technique? J Arthroplasty 29(5):982–988CrossRefPubMed
15.
go back to reference De Vil J, Almqvist KF, Vanheeren P, Boone B, Verdonk R (2008) Knee arthrodesis with an intramedullary nail: a retrospective study. Knee Surg Sports Traumatol Arthrosc 16(7):645–650CrossRefPubMed De Vil J, Almqvist KF, Vanheeren P, Boone B, Verdonk R (2008) Knee arthrodesis with an intramedullary nail: a retrospective study. Knee Surg Sports Traumatol Arthrosc 16(7):645–650CrossRefPubMed
16.
go back to reference Bargiotas K, Wohlrab D, Sewecke JJ, Lavinge G, Demeo PJ, Sotereanos NG (2006) Arthrodesis of the knee with a long intramedullary nail following the failure of a total knee arthroplasty as the result of infection. J Bone Joint Surg Am 88(3):553–558PubMed Bargiotas K, Wohlrab D, Sewecke JJ, Lavinge G, Demeo PJ, Sotereanos NG (2006) Arthrodesis of the knee with a long intramedullary nail following the failure of a total knee arthroplasty as the result of infection. J Bone Joint Surg Am 88(3):553–558PubMed
17.
go back to reference Engh GA, Ammeen DJ (1998) Classification and preoperative radiographic evaluation: knee. Orthop Clin North Am 29(2):205–217CrossRefPubMed Engh GA, Ammeen DJ (1998) Classification and preoperative radiographic evaluation: knee. Orthop Clin North Am 29(2):205–217CrossRefPubMed
18.
go back to reference Engh GA, Ammeen DJ (1999) Bone loss with revision total knee arthroplasty: defect classification and alternatives for reconstruction. Instr Course Lect 48:167–175PubMed Engh GA, Ammeen DJ (1999) Bone loss with revision total knee arthroplasty: defect classification and alternatives for reconstruction. Instr Course Lect 48:167–175PubMed
19.
go back to reference Abbas AM, Williams RL, Khan WS, Ghandour A, Morgan-Jones RL (2016) Tibial crest osteotomy in extensile knee exposure-a modified, low-energy, suture technique. J Arthroplasty 31(2):383–388CrossRefPubMed Abbas AM, Williams RL, Khan WS, Ghandour A, Morgan-Jones RL (2016) Tibial crest osteotomy in extensile knee exposure-a modified, low-energy, suture technique. J Arthroplasty 31(2):383–388CrossRefPubMed
20.
go back to reference Weber FA, Lautenbach EE (1986) Revision of infected total hip arthroplasty. Clin Orthop Relat Res 211:108–115 Weber FA, Lautenbach EE (1986) Revision of infected total hip arthroplasty. Clin Orthop Relat Res 211:108–115
21.
go back to reference Hashmi MA, Norman P, Saleh M (2004) The management of chronic osteomyelitis using the Lautenbach method. J Bone Joint Surg Br 86(2):269–275CrossRefPubMed Hashmi MA, Norman P, Saleh M (2004) The management of chronic osteomyelitis using the Lautenbach method. J Bone Joint Surg Br 86(2):269–275CrossRefPubMed
22.
go back to reference McCraw JB, Fishman JH, Sharzer LA (1978) The versatile gastrocnemius myocutaneous flap. Plast Reconstr Surg 62(1):15–23CrossRefPubMed McCraw JB, Fishman JH, Sharzer LA (1978) The versatile gastrocnemius myocutaneous flap. Plast Reconstr Surg 62(1):15–23CrossRefPubMed
23.
go back to reference Ellingsen DE, Rand JA (1994) Intramedullary arthrodesis of the knee after failed total knee arthroplasty. J Bone Joint Surg Am 76(6):870–877CrossRefPubMed Ellingsen DE, Rand JA (1994) Intramedullary arthrodesis of the knee after failed total knee arthroplasty. J Bone Joint Surg Am 76(6):870–877CrossRefPubMed
24.
go back to reference Talmo CT, Bono JV, Figgie MP, Sculco TP, Laskin RS, Windsor RE (2007) Intramedullary arthrodesis of the knee in the treatment of sepsis after TKR. HSS J 3(1):83–88CrossRefPubMedPubMedCentral Talmo CT, Bono JV, Figgie MP, Sculco TP, Laskin RS, Windsor RE (2007) Intramedullary arthrodesis of the knee in the treatment of sepsis after TKR. HSS J 3(1):83–88CrossRefPubMedPubMedCentral
25.
go back to reference Waldman BJ, Mont MA, Payman KR, Freiberg AA, Windsor RE, Sculco TP et al (1999) Infected total knee arthroplasty treated with arthrodesis using a modular nail. Clin Orthop Relat Res 367:230–237CrossRef Waldman BJ, Mont MA, Payman KR, Freiberg AA, Windsor RE, Sculco TP et al (1999) Infected total knee arthroplasty treated with arthrodesis using a modular nail. Clin Orthop Relat Res 367:230–237CrossRef
26.
go back to reference Leroux B, Aparicio G, Fontanin N, Ohl X, Madi K, Dehoux E et al (2013) Arthrodesis in septic knees using a long intramedullary nail: 17 consecutive cases. Orthop Traumatol Surg Res 99(4):399–404CrossRefPubMed Leroux B, Aparicio G, Fontanin N, Ohl X, Madi K, Dehoux E et al (2013) Arthrodesis in septic knees using a long intramedullary nail: 17 consecutive cases. Orthop Traumatol Surg Res 99(4):399–404CrossRefPubMed
27.
go back to reference Kuchinad R, Fourman MS, Fragomen AT, Rozbruch SR (2014) Knee arthrodesis as limb salvage for complex failures of total knee arthroplasty. J Arthroplasty 29(11):2150–2155CrossRefPubMed Kuchinad R, Fourman MS, Fragomen AT, Rozbruch SR (2014) Knee arthrodesis as limb salvage for complex failures of total knee arthroplasty. J Arthroplasty 29(11):2150–2155CrossRefPubMed
28.
go back to reference Klinger HM, Spahn G, Schultz W, Baums MH (2006) Arthrodesis of the knee after failed infected total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 14(5):447–453CrossRefPubMed Klinger HM, Spahn G, Schultz W, Baums MH (2006) Arthrodesis of the knee after failed infected total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 14(5):447–453CrossRefPubMed
29.
go back to reference Hawi N, Kendoff D, Citak M, Gehrke T, Haasper C (2015) Septic single-stage knee arthrodesis after failed total knee arthroplasty using a cemented coupled nail. Bone Joint J 97-B(5):649–653CrossRefPubMed Hawi N, Kendoff D, Citak M, Gehrke T, Haasper C (2015) Septic single-stage knee arthrodesis after failed total knee arthroplasty using a cemented coupled nail. Bone Joint J 97-B(5):649–653CrossRefPubMed
30.
go back to reference Parvizi J, Gehrke T, Chen AF (2013) Proceedings of the international consensus on periprosthetic joint infection. Bone Joint J 95-B(11):1450–1452CrossRefPubMed Parvizi J, Gehrke T, Chen AF (2013) Proceedings of the international consensus on periprosthetic joint infection. Bone Joint J 95-B(11):1450–1452CrossRefPubMed
31.
go back to reference Schmolders J, Hischebeth GT, Friedrich MJ, Randau TM, Wimmer MD, Kohlhof H et al (2014) Evidence of MRSE on a gentamicin and vancomycin impregnated polymethyl-methacrylate (PMMA) bone cement spacer after two-stage exchange arthroplasty due to periprosthetic joint infection of the knee. BMC Infect Dis 14:144CrossRefPubMedPubMedCentral Schmolders J, Hischebeth GT, Friedrich MJ, Randau TM, Wimmer MD, Kohlhof H et al (2014) Evidence of MRSE on a gentamicin and vancomycin impregnated polymethyl-methacrylate (PMMA) bone cement spacer after two-stage exchange arthroplasty due to periprosthetic joint infection of the knee. BMC Infect Dis 14:144CrossRefPubMedPubMedCentral
32.
go back to reference Kilgus DJ, Howe DJ, Strang A (2002) Results of periprosthetic hip and knee infections caused by resistant bacteria. Clin Orthop Relat Res 404:116–124CrossRef Kilgus DJ, Howe DJ, Strang A (2002) Results of periprosthetic hip and knee infections caused by resistant bacteria. Clin Orthop Relat Res 404:116–124CrossRef
33.
go back to reference Ries MD (2001) Vancomycin-resistant Enterococcus infected total knee arthroplasty. J Arthroplasty 16(6):802–805CrossRefPubMed Ries MD (2001) Vancomycin-resistant Enterococcus infected total knee arthroplasty. J Arthroplasty 16(6):802–805CrossRefPubMed
34.
go back to reference Hak DJ, Lieberman JR, Finerman GA (1995) Single plane and biplane external fixators for knee arthrodesis. Clin Orthop Relat Res 316:134–144 Hak DJ, Lieberman JR, Finerman GA (1995) Single plane and biplane external fixators for knee arthrodesis. Clin Orthop Relat Res 316:134–144
35.
go back to reference Incavo SJ, Lilly JW, Bartlett CS, Churchill DL (2000) Arthrodesis of the knee: experience with intramedullary nailing. J Arthroplasty 15(7):871–876CrossRefPubMed Incavo SJ, Lilly JW, Bartlett CS, Churchill DL (2000) Arthrodesis of the knee: experience with intramedullary nailing. J Arthroplasty 15(7):871–876CrossRefPubMed
36.
go back to reference MacDonald JH, Agarwal S, Lorei MP, Johanson NA, Freiberg AA (2006) Knee arthrodesis. J Am Acad Orthop Surg 14(3):154–163CrossRefPubMed MacDonald JH, Agarwal S, Lorei MP, Johanson NA, Freiberg AA (2006) Knee arthrodesis. J Am Acad Orthop Surg 14(3):154–163CrossRefPubMed
37.
go back to reference Scarponi S, Drago L, Romanò D, Logoluso N, Peccati A, Meani E, Romanò CL (2014) Cementless modular intramedullary nail without bone-on-bone fusion as a salvage procedure in chronically infected total knee prosthesis: long-term results. Int Orthop 38(2):413–418CrossRefPubMed Scarponi S, Drago L, Romanò D, Logoluso N, Peccati A, Meani E, Romanò CL (2014) Cementless modular intramedullary nail without bone-on-bone fusion as a salvage procedure in chronically infected total knee prosthesis: long-term results. Int Orthop 38(2):413–418CrossRefPubMed
38.
go back to reference Putman S, Kern G, Senneville E, Beltrand E, Migaud H (2013) Knee arthrodesis using a customised modular intramedullary nail in failed infected total knee arthroplasty. Orthop Traumatol Surg Res 99(4):391–398CrossRefPubMed Putman S, Kern G, Senneville E, Beltrand E, Migaud H (2013) Knee arthrodesis using a customised modular intramedullary nail in failed infected total knee arthroplasty. Orthop Traumatol Surg Res 99(4):391–398CrossRefPubMed
39.
go back to reference Gross TP, Liu F (2013) Total knee arthroplasty with fully porous-coated stems for the treatment of large bone defects. J Arthroplasty 28(4):598–603CrossRefPubMed Gross TP, Liu F (2013) Total knee arthroplasty with fully porous-coated stems for the treatment of large bone defects. J Arthroplasty 28(4):598–603CrossRefPubMed
40.
go back to reference Agarwal S, Azam A, Morgan-Jones R (2013) Metal metaphyseal sleeves in revision total knee replacement. Bone Joint J 95-B(12):1640–1644CrossRefPubMed Agarwal S, Azam A, Morgan-Jones R (2013) Metal metaphyseal sleeves in revision total knee replacement. Bone Joint J 95-B(12):1640–1644CrossRefPubMed
Metadata
Title
Knee arthrodesis with a long intramedullary nail as limb salvage for complex periprosthetic infections
Authors
Nima Razii
Ammar M. I. Abbas
Rahul Kakar
Sanjeev Agarwal
Rhidian Morgan-Jones
Publication date
01-12-2016
Publisher
Springer Paris
Published in
European Journal of Orthopaedic Surgery & Traumatology / Issue 8/2016
Print ISSN: 1633-8065
Electronic ISSN: 1432-1068
DOI
https://doi.org/10.1007/s00590-016-1827-2

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