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01-01-2019 | Original Article

Factors associated with having an indication for surgery in adult spinal deformity: an international european multicentre study

Authors: S. Richner-Wunderlin, A. F. Mannion, A. Vila-Casademunt, F. Pellise, M. Serra-Burriel, B. Seifert, E. Aghayev, E. Acaroglu, A. Alanay, F. J. S. Pérez-Grueso, I. Obeid, F. Kleinstück, European Spine Study Group (ESSG)

Published in: European Spine Journal | Issue 1/2019

Abstract

Purpose

The aim of this study was to evaluate factors that distinguish between patients with adult spinal deformity (ASD) with and without an indication for surgery, irrespective of their final treatment.

Methods

Baseline variables (demographics, medical history, outcome measures, coronal, sagittal and neurologic parameters) were evaluated in a multicentre, prospective cohort of patients with ASD. Multivariable analyses were carried out for idiopathic and degenerative patients separately with the dependent variable being “indication for surgery” and baseline parameters as independent variables.

Results

In total, 342 patients with degenerative ASD and 624 patients with idiopathic ASD were included in the multivariable models. In patients with degenerative ASD, the parameters associated with having an indication for surgery were greater self-rated disability on the Oswestry Disability Index [odds ratio (OR) 1.04, 95% confidence interval (CI) 1.02–1.07] and a lower thoracic kyphosis (OR 0.97 95% CI 0.95–0.99), whereas in patients with idiopathic ASD, it was lower (worse) SRS self-image scores (OR 0.45 95% CI 0.32–0.64), a higher value for the major Cobb angle (OR 1.03 95% CI 1.01–1.05), lower age (OR 0.96 95% CI 0.95–0.98), prior decompression (OR 3.76 95% CI 1.00–14.08), prior infiltration (OR 2.23 95% CI 1.12–4.43), and the presence of rotatory subluxation (OR 1.98 95% CI 1.11–3.54) and sagittal subluxation (OR 4.38 95% CI 1.61–11.95).

Conclusion

Specific sets of variables were found to be associated with an indication for surgery in patients with ASD. These should be investigated in relation to patient outcomes for their potential to guide the future development of decision aids in the treatment of ASD.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.

Available only for authorised users

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Title: Factors associated with having an indication for surgery in adult spinal deformity: an international european multicentre study
Authors: S. Richner-Wunderlin
A. F. Mannion
A. Vila-Casademunt
F. Pellise
M. Serra-Burriel
B. Seifert
E. Aghayev
E. Acaroglu
A. Alanay
F. J. S. Pérez-Grueso
I. Obeid
F. Kleinstück
European Spine Study Group (ESSG)
Publication date: 01-01-2019
Publisher: Springer Berlin Heidelberg
Published in: European Spine Journal / Issue 1/2019
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-018-5754-2

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Factors associated with having an indication for surgery in adult spinal deformity: an international european multicentre study

Abstract

Purpose

Methods

Results

Conclusion

Graphical abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

Graphical abstract

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