Skip to main content
Top
Published in: European Spine Journal 1/2019

Open Access 01-01-2019 | Original Article

The appropriate management of persisting pain after spine surgery: a European panel study with recommendations based on the RAND/UCLA method

Authors: Volker M. Tronnier, Sam Eldabe, Jörg Franke, Frank Huygen, Philippe Rigoard, Javier de Andres Ares, Richard Assaker, Alejandro Gomez-Rice, Marco La Grua, Maarten Moens, Lieven Moke, Christophe Perruchoud, Nasir A. Quraishi, Dominique A. Rothenfluh, Pedram Tabatabaei, Koen Van Boxem, Carmen Vleggeert-Lankamp, Björn Zoëga, Herman J. Stoevelaar

Published in: European Spine Journal | Issue 1/2019

Login to get access

Abstract

Purpose

Management of patients with persisting pain after spine surgery (PPSS) shows significant variability, and there is limited evidence from clinical studies to support treatment choice in daily practice. This study aimed to develop patient-specific recommendations on the management of PPSS.

Methods

Using the RAND/UCLA appropriateness method (RUAM), an international panel of 6 neurosurgeons, 6 pain specialists, and 6 orthopaedic surgeons assessed the appropriateness of 4 treatment options (conservative, minimally invasive, neurostimulation, and re-operation) for 210 clinical scenarios. These scenarios were unique combinations of patient characteristics considered relevant to treatment choice. Appropriateness had to be expressed on a 9-point scale (1 = extremely inappropriate, 9 = extremely appropriate). A treatment was considered appropriate if the median score was ≥ 7 in the absence of disagreement (≥ 1/3 of ratings in each of the opposite sections 1–3 and 7–9).

Results

Appropriateness outcomes showed clear and specific patterns. In 48% of the scenarios, exclusively one of the 4 treatments was appropriate. Conservative treatment was usually considered appropriate for patients without clear anatomic abnormalities and for those with new pain differing from the original symptoms. Neurostimulation was considered appropriate in the case of (predominant) neuropathic leg pain in the absence of conditions that may require surgical intervention. Re-operation could be considered for patients with recurrent disc, spinal/foraminal stenosis, or spinal instability.

Conclusions

Using the RUAM, an international multidisciplinary panel established criteria for appropriate treatment choice in patients with PPSS. These may be helpful to educate physicians and to improve consistency and quality of care.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.
Appendix
Available only for authorised users
Literature
5.
17.
go back to reference El Barzouhi A, Verwoerd AJ, Peul WC, Verhagen AP, Lycklama à Nijeholt GJ, Van der Kallen BF, Koes BW, Vleggeert-Lankamp CL; Leiden-The Hague Spine Intervention Prognostic Study Group (2016) Prognostic value of magnetic resonance imaging findings in patients with sciatica. J Neurosurg Spine 24:978–985. https://doi.org/10.3171/2015.10.SPINE15858 CrossRef El Barzouhi A, Verwoerd AJ, Peul WC, Verhagen AP, Lycklama à Nijeholt GJ, Van der Kallen BF, Koes BW, Vleggeert-Lankamp CL; Leiden-The Hague Spine Intervention Prognostic Study Group (2016) Prognostic value of magnetic resonance imaging findings in patients with sciatica. J Neurosurg Spine 24:978–985. https://​doi.​org/​10.​3171/​2015.​10.​SPINE15858 CrossRef
19.
go back to reference Grider JS, Manchikanti L, Carayannopoulos A, Sharma ML, Balog CC, Harned ME, Grami V, Justiz R, Nouri KH, Hayek SM, Vallejo R, Christo PJ (2016) Effectiveness of spinal cord stimulation in chronic spinal pain: a systematic review. Pain Physician 19:E33–E54PubMed Grider JS, Manchikanti L, Carayannopoulos A, Sharma ML, Balog CC, Harned ME, Grami V, Justiz R, Nouri KH, Hayek SM, Vallejo R, Christo PJ (2016) Effectiveness of spinal cord stimulation in chronic spinal pain: a systematic review. Pain Physician 19:E33–E54PubMed
20.
go back to reference Helm S 2nd, Racz GB, Gerdesmeyer L, Justiz R, Hayek SM, Kaplan ED, El Terany MA, Knezevic NN (2016) Percutaneous and endoscopic adhesiolysis in managing low back and lower extremity pain: a systematic review and meta-analysis. Pain Physician 19:E245–E282PubMed Helm S 2nd, Racz GB, Gerdesmeyer L, Justiz R, Hayek SM, Kaplan ED, El Terany MA, Knezevic NN (2016) Percutaneous and endoscopic adhesiolysis in managing low back and lower extremity pain: a systematic review and meta-analysis. Pain Physician 19:E245–E282PubMed
21.
go back to reference Cho JH, Lee JH, Song KS, Hong JY, Joo YS, Lee DH, Hwang CJ, Lee CS (2017) Treatment outcomes for patients with failed back surgery. Pain Physician 20:E29–E43PubMed Cho JH, Lee JH, Song KS, Hong JY, Joo YS, Lee DH, Hwang CJ, Lee CS (2017) Treatment outcomes for patients with failed back surgery. Pain Physician 20:E29–E43PubMed
23.
go back to reference Manchikanti L, Abdi S, Atluri S et al (2013) An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations. Pain Physician 16(Suppl):S49–S283PubMed Manchikanti L, Abdi S, Atluri S et al (2013) An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations. Pain Physician 16(Suppl):S49–S283PubMed
27.
go back to reference Van Buyten JP, Linderoth B (2010) “The failed back surgery syndrome”: definition and therapeutic algorithms—an update. Eur J Pain Suppl 4:273–286CrossRef Van Buyten JP, Linderoth B (2010) “The failed back surgery syndrome”: definition and therapeutic algorithms—an update. Eur J Pain Suppl 4:273–286CrossRef
28.
go back to reference Brook RH, Chassin MR, Fink A, Solomon DH, Kosecoff J, Park RE (1986) A method for the detailed assessment of the appropriateness of medical technologies. Int J Technol Assess Health Care 2:53–63CrossRefPubMed Brook RH, Chassin MR, Fink A, Solomon DH, Kosecoff J, Park RE (1986) A method for the detailed assessment of the appropriateness of medical technologies. Int J Technol Assess Health Care 2:53–63CrossRefPubMed
31.
33.
go back to reference Tobacman JK, Scott IU, Cyphert S, Zimmerman B (1999) Reproducibility of measures of overuse of cataract surgery by three physician panels. Med Care 37:37–45CrossRef Tobacman JK, Scott IU, Cyphert S, Zimmerman B (1999) Reproducibility of measures of overuse of cataract surgery by three physician panels. Med Care 37:37–45CrossRef
36.
go back to reference International Association for the Study of Pain (1994) Update of “pain terms, a current list with definitions and notes on usage". In: Merskey H, Bogduk N (eds) Classification of chronic pain. IASP Task Force on Taxonomy, 2nd edn. IASP Press, Seattle, pp 209–214. https://www.iasp-pain.org. Accessed 8 May 2018 International Association for the Study of Pain (1994) Update of “pain terms, a current list with definitions and notes on usage". In: Merskey H, Bogduk N (eds) Classification of chronic pain. IASP Task Force on Taxonomy, 2nd edn. IASP Press, Seattle, pp 209–214. https://​www.​iasp-pain.​org. Accessed 8 May 2018
37.
go back to reference Ferraro F, Jacopetti M, Spallone V, Padua L, Traballesi M, Brunelli S, Cantarella C, Ciotti C, Coraci D, Dalla Toffola E, Mandrini S, Morone G, Pazzaglia C, Romano M, Schenone A, Togni R, Tamburin S, Italian Consensus conference on pain in neurorehabilitation (ICCPN) (2016) Diagnosis and treatment of pain in plexopathy, radiculopathy, peripheral neuropathy and phantom limb pain. Evidence and recommendations from the Italian Consensus Conference on Pain on Neurorehabilitation. Eur J Phys Rehabil Med 52:855–866PubMed Ferraro F, Jacopetti M, Spallone V, Padua L, Traballesi M, Brunelli S, Cantarella C, Ciotti C, Coraci D, Dalla Toffola E, Mandrini S, Morone G, Pazzaglia C, Romano M, Schenone A, Togni R, Tamburin S, Italian Consensus conference on pain in neurorehabilitation (ICCPN) (2016) Diagnosis and treatment of pain in plexopathy, radiculopathy, peripheral neuropathy and phantom limb pain. Evidence and recommendations from the Italian Consensus Conference on Pain on Neurorehabilitation. Eur J Phys Rehabil Med 52:855–866PubMed
39.
go back to reference North RB, Kidd DH, Farrokhi F, Piantadosi SA (2005) Spinal cord stimulation versus repeated lumbosacral spine surgery for chronic pain: a randomized, controlled trial. Neurosurgery 56:98–106CrossRefPubMed North RB, Kidd DH, Farrokhi F, Piantadosi SA (2005) Spinal cord stimulation versus repeated lumbosacral spine surgery for chronic pain: a randomized, controlled trial. Neurosurgery 56:98–106CrossRefPubMed
40.
go back to reference Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O'Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, North RB (2007) Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome. Pain 132:179–188. https://doi.org/10.1016/j.pain.2007.07.028 CrossRefPubMed Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O'Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, North RB (2007) Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome. Pain 132:179–188. https://​doi.​org/​10.​1016/​j.​pain.​2007.​07.​028 CrossRefPubMed
45.
go back to reference Nijs J, Apeldoorn A, Hallegraeff H, Clark J, Smeets R, Malfliet A, Girbes EL, De Kooning M, Ickmans K (2015) Low back pain: guidelines for the clinical classification of predominant neuropathic, nociceptive, or central sensitization pain. Pain Physician 18:E333–E346PubMed Nijs J, Apeldoorn A, Hallegraeff H, Clark J, Smeets R, Malfliet A, Girbes EL, De Kooning M, Ickmans K (2015) Low back pain: guidelines for the clinical classification of predominant neuropathic, nociceptive, or central sensitization pain. Pain Physician 18:E333–E346PubMed
Metadata
Title
The appropriate management of persisting pain after spine surgery: a European panel study with recommendations based on the RAND/UCLA method
Authors
Volker M. Tronnier
Sam Eldabe
Jörg Franke
Frank Huygen
Philippe Rigoard
Javier de Andres Ares
Richard Assaker
Alejandro Gomez-Rice
Marco La Grua
Maarten Moens
Lieven Moke
Christophe Perruchoud
Nasir A. Quraishi
Dominique A. Rothenfluh
Pedram Tabatabaei
Koen Van Boxem
Carmen Vleggeert-Lankamp
Björn Zoëga
Herman J. Stoevelaar
Publication date
01-01-2019
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 1/2019
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-018-5711-0

Other articles of this Issue 1/2019

European Spine Journal 1/2019 Go to the issue