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European Spine Journal
Published in: European Spine Journal 12/2012

Open Access 01-12-2012 | Original Article

Detecting relevant changes and responsiveness of Neck Pain and Disability Scale and Neck Disability Index

Authors: Wim Jorritsma, Pieter U. Dijkstra, Grietje E. de Vries, Jan H. B. Geertzen, Michiel F. Reneman

Published in: European Spine Journal | Issue 12/2012

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Abstract

Purpose

To investigate relevant change on the Neck Pain and Disability Scale (NPAD) and Neck Disability Index (NDI) and which questionnaire is the most responsive in patients with non-specific chronic neck pain (CNP).

Methods

Seventy-six patients with non-specific CNP in an outpatient tertiary rehabilitation setting were dichotomized into “improved” and “stable” based on global perceived effect (GPE) scores. To investigate relevant change minimal detectable change (MDC) and minimal important change (MIC) with the receiver operator characteristic (ROC) cut-off point were assessed. Comparison of responsiveness was performed using areas under the ROC curve (AUC) and correlations between change scores of NPAD and NDI, and GPE.

Results

MDC and MIC on NPAD (scale 0–100) were 31.7 and 11.5 points, respectively. MDC and MIC on NDI (scale 0–50) were 8.4 and 3.5 points, respectively. Changes should exceed this MDC or MIC cut-off to be interpreted as relevant. AUC was 0.75 for both NPAD and NDI. Correlations between change scores of NPAD and NDI, and GPE were, respectively, 0.48 (95 % CI 0.29–0.64) and 0.49 (95 % CI 0.30–0.64).

Conclusions

Relevant change on both NPAD and NDI assessed with MDC and MIC resulted in different cut-offs and consequently with different amounts of certainty that the patient is improved. Responsiveness of NPAD and NDI was similar.
Literature
1.
Beaton DE (2000) Understanding the relevance of measured change through studies of responsiveness. Spine (Phila Pa 1976) 25:3192–3199CrossRef
2.
3.
Bolton JE (2004) Sensitivity and specificity of outcome measures in patients with neck pain: detecting clinically significant improvement. Spine (Phila Pa 1976) 29:2410–2417CrossRef
4.
Bremerich FH, Grob D, Dvorak J, Mannion AF (2008) The Neck Pain and Disability Scale: cross-cultural adaptation into German and evaluation of its psychometric properties in chronic neck pain and C1–2 fusion patients. Spine 33:1018–1027PubMedCrossRef
5.
Carreon LY, Glassman SD, Campbell MJ, Anderson PA (2010) Neck Disability Index, short form-36 physical component summary, and pain scales for neck and arm pain: the minimum clinically important difference and substantial clinical benefit after cervical spine fusion. Spine J 10:469–474PubMedCrossRef
6.
Cleland JA, Fritz JM, Whitman JM, Palmer JA (2006) The reliability and construct validity of the Neck Disability Index and patient specific functional scale in patients with cervical radiculopathy. Spine (Phila Pa 1976) 31:598–602CrossRef
7.
Cleland JA, Childs JD, Whitman JM (2008) Psychometric properties of the Neck Disability Index and Numeric Pain Rating Scale in patients with mechanical neck pain. Arch Phys Med Rehabil 89:69–74PubMedCrossRef
8.
Copay AG, Subach BR, Glassman SD, Polly DW Jr, Schuler TC (2007) Understanding the minimum clinically important difference: a review of concepts and methods. Spine J 7:541–546PubMedCrossRef
9.
Copay AG, Glassman SD, Subach BR, Berven S, Schuler TC, Carreon LY (2008) Minimum clinically important difference in lumbar spine surgery patients: a choice of methods using the Oswestry Disability Index, Medical Outcomes Study questionnaire Short Form 36, and pain scales. Spine J 8:968–974PubMedCrossRef
10.
Crosby RD, Kolotkin RL, Williams GR (2003) Defining clinically meaningful change in health-related quality of life. J Clin Epidemiol 56:395–407PubMedCrossRef
11.
de Vet HC, Ostelo RW, Terwee CB, van der RN, Knol DL, Beckerman H, Boers M, Bouter LM (2007) Minimally important change determined by a visual method integrating an anchor-based and a distribution-based approach. Qual Life Res 16:131–142PubMedCrossRef
12.
de Vet HC, Terluin B, Knol DL, Roorda LD, Mokkink LB, Ostelo RW, Hendriks EJ, Bouter LM, Terwee CB (2010) Three ways to quantify uncertainty in individually applied “minimally important change” values. J Clin Epidemiol 63:37–45PubMedCrossRef
13.
Ferrari R, Russell AS (2003) Regional musculoskeletal conditions: neck pain. Best Pract Res Clin Rheumatol 17:57–70PubMedCrossRef
14.
Fischer D, Stewart AL, Bloch DA, Lorig K, Laurent D, Holman H (1999) Capturing the patient’s view of change as a clinical outcome measure. JAMA 282:1157–1162PubMedCrossRef
15.
Gatchel RJ, Mayer TG (2010) Testing minimal clinically important difference: consensus or conundrum? Spine J 10:321–327PubMedCrossRef
16.
Goolkasian P, Wheeler AH, Gretz SS (2002) The neck pain and disability scale: test-retest reliability and construct validity. Clin J Pain 18:245–250PubMedCrossRef
17.
Jaeschke R, Singer J, Guyatt GH (1989) Measurement of health status. Ascertaining the minimal clinically important difference. Control Clin Trials 10:407–415PubMedCrossRef
18.
Jorritsma W, de Vries GE, Geertzen JH, Dijkstra PU, Reneman MF (2010) Neck Pain and Disability Scale and the Neck Disability Index: reproducibility of the Dutch Language Versions. Eur Spine J 19:1695–1701PubMedCrossRef
19.
Jorritsma W, de Vries GE, Dijkstra PU, Geertzen JH, Reneman MF (2012) Neck Pain and Disability Scale and Neck Disability Index: validity of Dutch language versions. Eur Spine J 21:93–100PubMedCrossRef
20.
Köke AJA, Heuts PHTG, Vlaeyen JWS (1996) Neck Disability Index. Pain Knowledge Center, University Medical Center Maastricht, Measurement instruments chronic pain. (Pijn Kennis Centrum, Academisch Ziekenhuis Maastricht, Meetinstrumenten chronische pijn), Maastricht., Maastricht
21.
Kose G, Hepguler S, Atamaz F, Oder G (2007) A comparison of four disability scales for Turkish patients with neck pain. J Rehabil Med 39:358–362PubMedCrossRef
22.
Lee H, Nicholson LL, Adams RD, Maher CG, Halaki M, Bae SS (2006) Development and psychometric testing of Korean language versions of 4 neck pain and disability questionnaires. Spine 31:1841–1845PubMedCrossRef
23.
Mannion AF, Porchet F, Kleinstuck FS, Lattig F, Jeszenszky D, Bartanusz V, Dvorak J, Grob D (2009) The quality of spine surgery from the patient’s perspective: part 2. Minimal clinically important difference for improvement and deterioration as measured with the Core Outcome Measures Index. Eur Spine J 18(Suppl 3):374–379PubMedCrossRef
24.
Ngo T, Stupar M, Cote P, Boyle E, Shearer H (2010) A study of the test-retest reliability of the self-perceived general recovery and self-perceived change in neck pain questions in patients with recent whiplash-associated disorders. Eur Spine J 19:957–962PubMedCrossRef
25.
Nicholas MK, Linton SJ, Watson PJ, Main CJ, “Decade of the Flags” Working Group (2011) Early identification and management of psychological risk factors (“yellow flags”) in patients with low back pain: a reappraisal. Phys Ther 91:737–753PubMedCrossRef
26.
Nordin M, Carragee EJ, Hogg-Johnson S, Weiner SS, Hurwitz EL, Peloso PM, Guzman J, van der Velde G, Carroll LJ, Holm LW, Cote P, Cassidy JD, Haldeman S (2009) Assessment of neck pain and its associated disorders: results of the bone and joint decade 2000–2010 task force on neck pain and its associated disorders. J Manip Physiol Ther 32:S117–S140CrossRef
27.
Norman GR, Stratford P, Regehr G (1997) Methodological problems in the retrospective computation of responsiveness to change: the lesson of Cronbach. J Clin Epidemiol 50:869–879PubMedCrossRef
28.
Pietrobon R, Coeytaux RR, Carey TS, Richardson WJ, DeVellis RF (2002) Standard scales for measurement of functional outcome for cervical pain or dysfunction: a systematic review. Spine 27:515–522PubMedCrossRef
29.
Pool JJ, Ostelo RW, Hoving JL, Bouter LM, de Vet HC (2007) Minimal clinically important change of the Neck Disability Index and the Numerical Rating Scale for patients with neck pain. Spine (Phila Pa 1976) 32:3047–3051CrossRef
30.
Portney LG, Watkins MP (2000) Foundations of Clinical Research, 2nd edn. Prentice Hall Health, Upper Saddle River
31.
Rubinstein SM, van Tulder M (2008) A best-evidence review of diagnostic procedures for neck and low-back pain. Best Pract Res Clin Rheumatol 22:471–482PubMedCrossRef
32.
Stewart M, Maher CG, Refshauge KM, Bogduk N, Nicholas M (2007) Responsiveness of pain and disability measures for chronic whiplash. Spine (Phila Pa 1976) 32:580–585CrossRef
33.
Stratford PW, Riddle DL, Binkley JM, Spadoni G, Westaway MD, Padfield B (1999) Using the Neck Disability Index to make decisions concerning individual patients. Physiother Can 51:107–112, 119
34.
Terwee CB, Bot SD, de Boer MR, van der Windt DA, Knol DL, Dekker J, Bouter LM, de Vet HC (2007) Quality criteria were proposed for measurement properties of health status questionnaires. J Clin Epidemiol 60:34–42PubMedCrossRef
35.
Vernon H, Mior S (1991) The Neck Disability Index: a study of reliability and validity. J Manip Physiol Ther 14:409–415
36.
Vos CJ, Verhagen AP, Koes BW (2006) Reliability and responsiveness of the Dutch version of the Neck Disability Index in patients with acute neck pain in general practice. Eur Spine J 15:1729–1736PubMedCrossRef
37.
Wheeler AH, Goolkasian P, Baird AC, Darden BV (1999) Development of the Neck Pain and Disability Scale. Item analysis, face, and criterion-related validity. Spine 24:1290–1294PubMedCrossRef
38.
Wlodyka-Demaille S, Poiraudeau S, Catanzariti JF, Rannou F, Fermanian J, Revel M (2004) The ability to change of three questionnaires for neck pain. Jt Bone Spine 71:317–326CrossRef
39.
Young BA, Walker MJ, Strunce JB, Boyles RE, Whitman JM, Childs JD (2009) Responsiveness of the Neck Disability Index in patients with mechanical neck disorders. Spine J 9:802–808PubMedCrossRef
40.
Young IA, Cleland JA, Michener LA, Brown C (2010) Reliability, construct validity, and responsiveness of the neck disability index, patient-specific functional scale, and numeric pain rating scale in patients with cervical radiculopathy. Am J Phys Med Rehabil 89:831–839PubMedCrossRef
Metadata
Title
Detecting relevant changes and responsiveness of Neck Pain and Disability Scale and Neck Disability Index
Authors
Wim Jorritsma
Pieter U. Dijkstra
Grietje E. de Vries
Jan H. B. Geertzen
Michiel F. Reneman
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
European Spine Journal / Issue 12/2012
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-012-2407-8

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