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Published in: European Spine Journal 12/2012

01-12-2012 | Original Article

Thoracic myelopathy caused by ossification of the yellow ligament in patients with posterior instrumented lumbar fusion

Authors: Kee-Yong Ha, Jun-Yeong Seo, Il-Nam Son, Young-Hoon Kim, Ki-Won Kim

Published in: European Spine Journal | Issue 12/2012

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Abstract

Purpose

The objective of this study was to investigate thoracic myelopathy caused by ossification of the yellow ligament (OYL) in patients with posterior instrumented lumbar fusion.

Methods

Seven patients, who had undergone posterior instrumented lumbar fusion, presented with thoracic myelopathy caused by OYL. No patient had a history of thoracic myelopathy at previous surgery. Instrumented fusions were performed from L1–5 in two patients, L2–5 in three patients and L1–S1 and L2–S1 in one patient each, respectively. MRI and CT scans were performed to confirm cord compression by OYL. Of the seven patients, six patients underwent decompressive laminectomy and OYL removal while one was treated conservatively.

Results

The average time to presentation after first surgery was 63.4 months. OYL was located at T9–10 in two patients, T11–12 in three patients, and T10–11 and T9–11 in one patient each, respectively. All patients had a myelopathic gait and the average Japanese Orthopaedic Association (JOA) score was 3.9, preoperatively. The average JOA score improved from 3.7 to 8 and the average recovery rate was 58.9 % in the six patients who underwent surgical intervention. However, the JOA score fell from 5 to 4 in the one patient who was treated conservatively.

Conclusions

We report seven patients who suffered from thoracic myelopathy after instrumented lumbar fusion. Surgeons must be aware of the possibility of thoracic myelopathy caused by OYL at the thoracolumbar junction, especially in patients with a complaint of gait disturbance after long instrumented lumbar fusion.
Literature
1.
go back to reference Park P, Garton HJ, Gala VC, Hoff JT, McGillicuddy JE (2004) Adjacent segment disease after lumbar or lumbosacral fusion: review of the literature. Spine (Phila Pa 1976) 29(17):1938–1944CrossRef Park P, Garton HJ, Gala VC, Hoff JT, McGillicuddy JE (2004) Adjacent segment disease after lumbar or lumbosacral fusion: review of the literature. Spine (Phila Pa 1976) 29(17):1938–1944CrossRef
2.
go back to reference Ha KY, Lee JS, Kim KW (2008) Degeneration of sacroiliac joint after instrumented lumbar or lumbosacral fusion: a prospective cohort study over five-year follow-up. Spine (Phila Pa 1976) 33(11):1192–1198CrossRef Ha KY, Lee JS, Kim KW (2008) Degeneration of sacroiliac joint after instrumented lumbar or lumbosacral fusion: a prospective cohort study over five-year follow-up. Spine (Phila Pa 1976) 33(11):1192–1198CrossRef
3.
go back to reference Ha KY, Schendel MJ, Lewis JL, Ogilvie JW (1993) Effect of immobilization and configuration on lumbar adjacent-segment biomechanics. J Spinal Disord 6(2):99–105PubMedCrossRef Ha KY, Schendel MJ, Lewis JL, Ogilvie JW (1993) Effect of immobilization and configuration on lumbar adjacent-segment biomechanics. J Spinal Disord 6(2):99–105PubMedCrossRef
4.
go back to reference Aota Y, Kumano K, Hirabayashi S (1995) Postfusion instability at the adjacent segments after rigid pedicle screw fixation for degenerative lumbar spinal disorders. J Spinal Disord 8(6):464–473PubMedCrossRef Aota Y, Kumano K, Hirabayashi S (1995) Postfusion instability at the adjacent segments after rigid pedicle screw fixation for degenerative lumbar spinal disorders. J Spinal Disord 8(6):464–473PubMedCrossRef
5.
go back to reference Etebar S, Cahill DW (1999) Risk factors for adjacent-segment failure following lumbar fixation with rigid instrumentation for degenerative instability. J Neurosurg 90(2 Suppl):163–169PubMed Etebar S, Cahill DW (1999) Risk factors for adjacent-segment failure following lumbar fixation with rigid instrumentation for degenerative instability. J Neurosurg 90(2 Suppl):163–169PubMed
6.
go back to reference Kim YJ, Bridwell KH, Lenke LG, Rhim S, Kim YW (2007) Is the T9, T11, or L1 the more reliable proximal level after adult lumbar or lumbosacral instrumented fusion to L5 or S1? Spine (Phila Pa 1976) 32(24):2653–2661CrossRef Kim YJ, Bridwell KH, Lenke LG, Rhim S, Kim YW (2007) Is the T9, T11, or L1 the more reliable proximal level after adult lumbar or lumbosacral instrumented fusion to L5 or S1? Spine (Phila Pa 1976) 32(24):2653–2661CrossRef
7.
go back to reference Kumar MN, Baklanov A, Chopin D (2001) Correlation between sagittal plane changes and adjacent segment degeneration following lumbar spine fusion. Eur Spine J 10(4):314–319PubMedCrossRef Kumar MN, Baklanov A, Chopin D (2001) Correlation between sagittal plane changes and adjacent segment degeneration following lumbar spine fusion. Eur Spine J 10(4):314–319PubMedCrossRef
8.
go back to reference Wiltse LL, Radecki SE, Biel HM, DiMartino PP, Oas RA, Farjalla G, Ravessoud FA, Wohletz C (1999) Comparative study of the incidence and severity of degenerative change in the transition zones after instrumented versus noninstrumented fusions of the lumbar spine. J Spinal Disord 12(1):27–33PubMedCrossRef Wiltse LL, Radecki SE, Biel HM, DiMartino PP, Oas RA, Farjalla G, Ravessoud FA, Wohletz C (1999) Comparative study of the incidence and severity of degenerative change in the transition zones after instrumented versus noninstrumented fusions of the lumbar spine. J Spinal Disord 12(1):27–33PubMedCrossRef
9.
go back to reference Pascal-Mousselard H, Smadja D, Cabre P, Raynaud M, Catonne Y (1998) Ossification of the ligamenta flava with severe myelopathy in a black patient. A case report. Spine (Phila Pa 1976) 23(14):1607–1608CrossRef Pascal-Mousselard H, Smadja D, Cabre P, Raynaud M, Catonne Y (1998) Ossification of the ligamenta flava with severe myelopathy in a black patient. A case report. Spine (Phila Pa 1976) 23(14):1607–1608CrossRef
10.
go back to reference Hirabayashi K, Miyakawa J, Satomi K, Maruyama T, Wakano K (1981) Operative results and postoperative progression of ossification among patients with ossification of cervical posterior longitudinal ligament. Spine (Phila Pa 1976) 6(4):354–364CrossRef Hirabayashi K, Miyakawa J, Satomi K, Maruyama T, Wakano K (1981) Operative results and postoperative progression of ossification among patients with ossification of cervical posterior longitudinal ligament. Spine (Phila Pa 1976) 6(4):354–364CrossRef
11.
go back to reference Nagata H, Schendel MJ, Transfeldt EE, Lewis JL (1993) The effects of immobilization of long segments of the spine on the adjacent and distal facet force and lumbosacral motion. Spine (Phila Pa 1976) 18(16):2471–2479CrossRef Nagata H, Schendel MJ, Transfeldt EE, Lewis JL (1993) The effects of immobilization of long segments of the spine on the adjacent and distal facet force and lumbosacral motion. Spine (Phila Pa 1976) 18(16):2471–2479CrossRef
12.
go back to reference Chen WJ, Lai PL, Niu CC, Chen LH, Fu TS, Wong CB (2001) Surgical treatment of adjacent instability after lumbar spine fusion. Spine (Phila Pa 1976) 26(22):E519–E524CrossRef Chen WJ, Lai PL, Niu CC, Chen LH, Fu TS, Wong CB (2001) Surgical treatment of adjacent instability after lumbar spine fusion. Spine (Phila Pa 1976) 26(22):E519–E524CrossRef
13.
go back to reference Watanabe K, Lenke LG, Bridwell KH, Kim YJ, Koester L, Hensley M (2010) Proximal junctional vertebral fracture in adults after spinal deformity surgery using pedicle screw constructs: analysis of morphological features. Spine (Phila Pa 1976) 35(2):138–145CrossRef Watanabe K, Lenke LG, Bridwell KH, Kim YJ, Koester L, Hensley M (2010) Proximal junctional vertebral fracture in adults after spinal deformity surgery using pedicle screw constructs: analysis of morphological features. Spine (Phila Pa 1976) 35(2):138–145CrossRef
14.
go back to reference Yoshida M, Shima K, Taniguchi Y, Tamaki T, Tanaka T (1992) Hypertrophied ligamentum flavum in lumbar spinal canal stenosis. Pathogenesis and morphologic and immunohistochemical observation. Spine (Phila Pa 1976) 17(11):1353–1360CrossRef Yoshida M, Shima K, Taniguchi Y, Tamaki T, Tanaka T (1992) Hypertrophied ligamentum flavum in lumbar spinal canal stenosis. Pathogenesis and morphologic and immunohistochemical observation. Spine (Phila Pa 1976) 17(11):1353–1360CrossRef
15.
go back to reference Kaneyama S, Doita M, Nishida K, Shimomura T, Maeno K, Tamura Y, Kurosaka M, Yonenobu K (2008) Thoracic myelopathy due to ossification of the yellow ligament in young baseball pitchers. J Spinal Disord Tech 21(1):68–71PubMedCrossRef Kaneyama S, Doita M, Nishida K, Shimomura T, Maeno K, Tamura Y, Kurosaka M, Yonenobu K (2008) Thoracic myelopathy due to ossification of the yellow ligament in young baseball pitchers. J Spinal Disord Tech 21(1):68–71PubMedCrossRef
16.
go back to reference Chen Y, Lu XH, Yang LL, Chen DY (2009) Ossification of ligamentum flavum related to thoracic kyphosis after tuberculosis: case report and review of the literature. Spine (Phila Pa 1976) 34(1):E41–E44CrossRef Chen Y, Lu XH, Yang LL, Chen DY (2009) Ossification of ligamentum flavum related to thoracic kyphosis after tuberculosis: case report and review of the literature. Spine (Phila Pa 1976) 34(1):E41–E44CrossRef
17.
go back to reference Aizawa T, Sato T, Sasaki H, Kusakabe T, Morozumi N, Kokubun S (2006) Thoracic myelopathy caused by ossification of the ligamentum flavum: clinical features and surgical results in the Japanese population. J Neurosurg Spine 5(6):514–519PubMedCrossRef Aizawa T, Sato T, Sasaki H, Kusakabe T, Morozumi N, Kokubun S (2006) Thoracic myelopathy caused by ossification of the ligamentum flavum: clinical features and surgical results in the Japanese population. J Neurosurg Spine 5(6):514–519PubMedCrossRef
18.
go back to reference Lee CK (1988) Accelerated degeneration of the segment adjacent to a lumbar fusion. Spine (Phila Pa 1976) 13(3):375–377CrossRef Lee CK (1988) Accelerated degeneration of the segment adjacent to a lumbar fusion. Spine (Phila Pa 1976) 13(3):375–377CrossRef
19.
go back to reference Cheh G, Bridwell KH, Lenke LG, Buchowski JM, Daubs MD, Kim Y, Baldus C (2007) Adjacent segment disease followinglumbar/thoracolumbar fusion with pedicle screw instrumentation: a minimum 5-year follow-up. Spine (Phila Pa 1976) 32(20):2253–2257CrossRef Cheh G, Bridwell KH, Lenke LG, Buchowski JM, Daubs MD, Kim Y, Baldus C (2007) Adjacent segment disease followinglumbar/thoracolumbar fusion with pedicle screw instrumentation: a minimum 5-year follow-up. Spine (Phila Pa 1976) 32(20):2253–2257CrossRef
20.
go back to reference Oxland TR, Lin RM, Panjabi MM (1992) Three-dimensional mechanical properties of the thoracolumbar junction. J Orthop Res 10(4):573–580PubMedCrossRef Oxland TR, Lin RM, Panjabi MM (1992) Three-dimensional mechanical properties of the thoracolumbar junction. J Orthop Res 10(4):573–580PubMedCrossRef
21.
go back to reference Smith DE, Godersky JC (1987) Thoracic spondylosis: an unusual cause of myelopathy. Neurosurgery 20(4):589–593PubMedCrossRef Smith DE, Godersky JC (1987) Thoracic spondylosis: an unusual cause of myelopathy. Neurosurgery 20(4):589–593PubMedCrossRef
22.
go back to reference Kim JH, Kim SS, Suk SI (2007) Incidence of proximal adjacent failure in adult lumbar deformity correction based on proximal fusion level. Asian Spine J 1(1):19–26PubMedCrossRef Kim JH, Kim SS, Suk SI (2007) Incidence of proximal adjacent failure in adult lumbar deformity correction based on proximal fusion level. Asian Spine J 1(1):19–26PubMedCrossRef
23.
go back to reference Nishiura I, Isozumi T, Nishihara K, Handa H, Koyama T (1999) Surgical approach to ossification of the thoracic yellow ligament. Surg Neurol 51(4):368–372PubMedCrossRef Nishiura I, Isozumi T, Nishihara K, Handa H, Koyama T (1999) Surgical approach to ossification of the thoracic yellow ligament. Surg Neurol 51(4):368–372PubMedCrossRef
24.
go back to reference Li KK, Chung OM, Chang YP, So YC (2002) Myelopathy caused by ossification of ligamentum flavum. Spine (Phila Pa 1976) 27(12):E308–E312CrossRef Li KK, Chung OM, Chang YP, So YC (2002) Myelopathy caused by ossification of ligamentum flavum. Spine (Phila Pa 1976) 27(12):E308–E312CrossRef
25.
go back to reference Okada K, Oka S, Tohge K, Ono K, Yonenobu K, Hosoya T (1991) Thoracic myelopathy caused by ossification of the ligamentum flavumclinicopathologic study and surgical treatment. Spine (Phila Pa 1976) 16(3):280–287CrossRef Okada K, Oka S, Tohge K, Ono K, Yonenobu K, Hosoya T (1991) Thoracic myelopathy caused by ossification of the ligamentum flavumclinicopathologic study and surgical treatment. Spine (Phila Pa 1976) 16(3):280–287CrossRef
26.
go back to reference Yonenobu K, Ebara S, Fujiwara K, Yamashita K, Ono K, Yamamoto T, Harada N, Ogino H, Ojima S (1987) Thoracic myelopathy secondary to ossification of the spinal ligament. J Neurosurg 66(4):511–518PubMedCrossRef Yonenobu K, Ebara S, Fujiwara K, Yamashita K, Ono K, Yamamoto T, Harada N, Ogino H, Ojima S (1987) Thoracic myelopathy secondary to ossification of the spinal ligament. J Neurosurg 66(4):511–518PubMedCrossRef
27.
go back to reference He S, Hussain N, Li S, Hou T (2005) Clinical and prognostic analysis of ossified ligamentum flavum in a Chinese population. J Neurosurg Spine 3(5):348–354PubMedCrossRef He S, Hussain N, Li S, Hou T (2005) Clinical and prognostic analysis of ossified ligamentum flavum in a Chinese population. J Neurosurg Spine 3(5):348–354PubMedCrossRef
28.
go back to reference Fong SY, Wong HK (2004) Thoracic myelopathy secondary to ligamentum flavum ossification. Ann Acad Med Singap 33(3):340–346PubMed Fong SY, Wong HK (2004) Thoracic myelopathy secondary to ligamentum flavum ossification. Ann Acad Med Singap 33(3):340–346PubMed
29.
go back to reference Miyakoshi N, Shimada Y, Suzuki T, Hongo M, Kasukawa Y, Okada K, Itoi E (2003) Factors related to long-term outcome after decompressive surgery for ossification of the ligamentum flavum of the thoracic spine. J Neurosurg 99(3 Suppl):251–256PubMed Miyakoshi N, Shimada Y, Suzuki T, Hongo M, Kasukawa Y, Okada K, Itoi E (2003) Factors related to long-term outcome after decompressive surgery for ossification of the ligamentum flavum of the thoracic spine. J Neurosurg 99(3 Suppl):251–256PubMed
30.
go back to reference Shiokawa K, Hanakita J, Suwa H, Saiki M, Oda M, Kajiwara M (2001) Clinical analysis and prognostic study of ossified ligamentum flavum of the thoracic spine. J Neurosurg 94(2 Suppl):221–226PubMed Shiokawa K, Hanakita J, Suwa H, Saiki M, Oda M, Kajiwara M (2001) Clinical analysis and prognostic study of ossified ligamentum flavum of the thoracic spine. J Neurosurg 94(2 Suppl):221–226PubMed
31.
go back to reference Sanghvi AV, Chhabra HS, Mascarenhas AA, Mittal VK, Sangondimath GM (2011) Thoracic myelopathy due to ossification of ligamentum flavum: a retrospective analysis of predictors of surgical outcome and factors affecting preoperative neurological status. Eur Spine J 20(2):205–215PubMedCrossRef Sanghvi AV, Chhabra HS, Mascarenhas AA, Mittal VK, Sangondimath GM (2011) Thoracic myelopathy due to ossification of ligamentum flavum: a retrospective analysis of predictors of surgical outcome and factors affecting preoperative neurological status. Eur Spine J 20(2):205–215PubMedCrossRef
Metadata
Title
Thoracic myelopathy caused by ossification of the yellow ligament in patients with posterior instrumented lumbar fusion
Authors
Kee-Yong Ha
Jun-Yeong Seo
Il-Nam Son
Young-Hoon Kim
Ki-Won Kim
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
European Spine Journal / Issue 12/2012
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-012-2413-x

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