Published in:
01-12-2019 | Tick | Case Report
Concurrent infection of Leptospira icterohaemorrhagiae, Hepatozoon canis and Anaplasma phagocytophilum in a Labrador Retriever dog and its therapeutic management
Authors:
Neeraj Thakur, G. E. Chethan, Akhilesh, C. Gaykwad, K. K. Reena, Anil Kumar, J. B. Rajesh, U. K. De, K. Mahendran, P. S. Banerjee
Published in:
Comparative Clinical Pathology
|
Issue 6/2019
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Abstract
In this report, concurrent infection of Leptospira interrogans serovar icterohaemorrhagiae, Hepatozoon canis and Anaplasma phagocytophilum in a Labrador Retriever dog and its successful therapeutic management have been described. A 3-year-old female dog was presented with a history of anorexia, fever, lethargy, weakness, vomiting, black-coloured faeces and yellowish urine. Clinical and laboratory examination revealed pyrexia, icteric mucous membranes, hepatomegaly, splenomegaly, anaemia, leukocytosis, thrombocytopaenia, hypoalbuminemia and hyperbilirubinemia. Hepatozoon canis and Anaplasma phagocytophilum infections were confirmed by blood smear examination. Leptospira icterohaemorrhagiae was confirmed by microscopic agglutination test (MAT). Animal was stabilised with polyionic fluids, and therapy was started with imidocarb dipropionate (6.6 mg/Kg, SC, single dose), doxycycline (5 mg/kg, PO, bid) for 28 days, N-acetyl cysteine (30 mg/Kg, IV, SID) for 5 days and fipronil (0.25%) spray for topical use. Supportive therapy was done with plasma volume expanders, multivitamins, haematinics and hepatoprotectants. The animal showed complete recovery after 2 months of therapy.