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Published in: Journal of Anesthesia 5/2016

01-10-2016 | Review Article

Sarcopenia in critically ill patients

Authors: Muhammet C. Kizilarslanoglu, Mehmet E. Kuyumcu, Yusuf Yesil, Meltem Halil

Published in: Journal of Anesthesia | Issue 5/2016

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Abstract

Sarcopenia occurring as a primary consequence of aging and secondary due to certain medical problems including chronic disease, malnutrition and inactivity is a progressive generalized loss of skeletal muscle mass, strength and function. The prevalence of sarcopenia increases with aging (approximately 5–13 % in the sixth and seventh decades). However, data showing the prevalence and clinical outcomes of sarcopenia in intensive care units (ICUs) are limited. A similar condition to sarcopenia in the ICU, called ICU-acquired weakness (ICU-AW), has been reported more frequently. Here, we aim to examine the importance of sarcopenia, especially ICU-AW, in ICU patients via related articles in Medline.
Literature
1.
go back to reference Wang C, Bai L. Sarcopenia in the elderly: basic and clinical issues. Geriatr Gerontol Int. 2012;12(3):388–96.PubMedCrossRef Wang C, Bai L. Sarcopenia in the elderly: basic and clinical issues. Geriatr Gerontol Int. 2012;12(3):388–96.PubMedCrossRef
5.
go back to reference Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinková E, Vandewoude M, Zamboni M. Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people. Age Ageing. 2010;39(4):412–23.PubMedPubMedCentralCrossRef Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinková E, Vandewoude M, Zamboni M. Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people. Age Ageing. 2010;39(4):412–23.PubMedPubMedCentralCrossRef
6.
go back to reference Stevens RD, Marshall SA, Cornblath DR, Hoke A, Needham DM, de Jonghe B, Ali NA, Sharshar TA. A framework for diagnosing and classifying intensive care unit-acquired weakness. Crit Care Med. 2009;37(10 Suppl):S299–308.PubMedCrossRef Stevens RD, Marshall SA, Cornblath DR, Hoke A, Needham DM, de Jonghe B, Ali NA, Sharshar TA. A framework for diagnosing and classifying intensive care unit-acquired weakness. Crit Care Med. 2009;37(10 Suppl):S299–308.PubMedCrossRef
7.
go back to reference van der Jagt M. Intensive care unit-acquired weakness. Crit care Med. 2010;38(7):1617–9 (author reply 9).PubMedCrossRef van der Jagt M. Intensive care unit-acquired weakness. Crit care Med. 2010;38(7):1617–9 (author reply 9).PubMedCrossRef
8.
9.
go back to reference Batt J, dos Santos CC, Cameron JI, Herridge MS. Intensive care unit-acquired weakness: clinical phenotypes and molecular mechanisms. Am J Respir Crit Care Med. 2013;187(3):238–46.PubMedCrossRef Batt J, dos Santos CC, Cameron JI, Herridge MS. Intensive care unit-acquired weakness: clinical phenotypes and molecular mechanisms. Am J Respir Crit Care Med. 2013;187(3):238–46.PubMedCrossRef
10.
go back to reference Kress JP, Hall JB. ICU-acquired weakness and recovery from critical illness. N Engl J Med. 2014;370(17):1626–35.PubMedCrossRef Kress JP, Hall JB. ICU-acquired weakness and recovery from critical illness. N Engl J Med. 2014;370(17):1626–35.PubMedCrossRef
11.
go back to reference Deem S. Intensive-care-unit-acquired muscle weakness. Respir Care. 2006;51(9):1042–52 (discussion 52–3).PubMed Deem S. Intensive-care-unit-acquired muscle weakness. Respir Care. 2006;51(9):1042–52 (discussion 52–3).PubMed
12.
go back to reference Schefold JC, Bierbrauer J, Weber-Carstens S. Intensive care unit-acquired weakness (ICUAW) and muscle wasting in critically ill patients with severe sepsis and septic shock. J Cachexia Sarcopenia Muscle. 2010;1(2):147–57.PubMedPubMedCentralCrossRef Schefold JC, Bierbrauer J, Weber-Carstens S. Intensive care unit-acquired weakness (ICUAW) and muscle wasting in critically ill patients with severe sepsis and septic shock. J Cachexia Sarcopenia Muscle. 2010;1(2):147–57.PubMedPubMedCentralCrossRef
13.
go back to reference Wollersheim T, Woehlecke J, Krebs M, Hamati J, Lodka D, Luther-Schroeder A, Langhans C, Haas K, Radtke T, Kleber C, Spies C, Labeit S, Schuelke M, Spuler S, Spranger J, Weber-Carstens S, Fielitz J. Dynamics of myosin degradation in intensive care unit-acquired weakness during severe critical illness. Intensive Care Med. 2014;40(4):528–38.PubMedCrossRef Wollersheim T, Woehlecke J, Krebs M, Hamati J, Lodka D, Luther-Schroeder A, Langhans C, Haas K, Radtke T, Kleber C, Spies C, Labeit S, Schuelke M, Spuler S, Spranger J, Weber-Carstens S, Fielitz J. Dynamics of myosin degradation in intensive care unit-acquired weakness during severe critical illness. Intensive Care Med. 2014;40(4):528–38.PubMedCrossRef
14.
go back to reference De Jonghe B, Sharshar T, Lefaucheur JP, Authier FJ, Durand-Zaleski I, Boussarsar M, Cerf C, Renaud E, Mesrati F, Carlet J, Raphaël JC, Outin H, Bastuji-Garin S. Paresis acquired in the intensive care unit: a prospective multicenter study. J Am Med Assoc. 2002;288(22):2859–67.CrossRef De Jonghe B, Sharshar T, Lefaucheur JP, Authier FJ, Durand-Zaleski I, Boussarsar M, Cerf C, Renaud E, Mesrati F, Carlet J, Raphaël JC, Outin H, Bastuji-Garin S. Paresis acquired in the intensive care unit: a prospective multicenter study. J Am Med Assoc. 2002;288(22):2859–67.CrossRef
15.
go back to reference Garnacho-Montero J, Amaya-Villar R, Garcia-Garmendia JL, Madrazo-Osuna J, Ortiz-Leyba C. Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay in septic patients. Crit Care Med. 2005;33(2):349–54.PubMedCrossRef Garnacho-Montero J, Amaya-Villar R, Garcia-Garmendia JL, Madrazo-Osuna J, Ortiz-Leyba C. Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay in septic patients. Crit Care Med. 2005;33(2):349–54.PubMedCrossRef
16.
go back to reference Ali NA, O’Brien JM Jr, Hoffmann SP, Phillips G, Garland A, Finley JC, Almoosa K, Hejal R, Wolf KM, Lemeshow S, Connors AF Jr, Marsh CB. Acquired weakness, handgrip strength, and mortality in critically ill patients. Am J Respir Crit Care Med. 2008;178(3):261–8.PubMedCrossRef Ali NA, O’Brien JM Jr, Hoffmann SP, Phillips G, Garland A, Finley JC, Almoosa K, Hejal R, Wolf KM, Lemeshow S, Connors AF Jr, Marsh CB. Acquired weakness, handgrip strength, and mortality in critically ill patients. Am J Respir Crit Care Med. 2008;178(3):261–8.PubMedCrossRef
17.
go back to reference Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper AB, Guest CB, Mazer CD, Mehta S, Stewart TE, Barr A, Cook D, Slutsky AS. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med. 2003;348(8):683–93.PubMedCrossRef Herridge MS, Cheung AM, Tansey CM, Matte-Martyn A, Diaz-Granados N, Al-Saidi F, Cooper AB, Guest CB, Mazer CD, Mehta S, Stewart TE, Barr A, Cook D, Slutsky AS. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med. 2003;348(8):683–93.PubMedCrossRef
18.
go back to reference Chelluri L, Im KA, Belle SH, Schulz R, Rotondi AJ, Donahoe MP, Sirio CA, Mendelsohn AB, Pinsky MR. Long-term mortality and quality of life after prolonged mechanical ventilation. Crit Care Med. 2004;32(1):61–9.PubMedCrossRef Chelluri L, Im KA, Belle SH, Schulz R, Rotondi AJ, Donahoe MP, Sirio CA, Mendelsohn AB, Pinsky MR. Long-term mortality and quality of life after prolonged mechanical ventilation. Crit Care Med. 2004;32(1):61–9.PubMedCrossRef
19.
go back to reference de Jonghe B, Lacherade JC, Sharshar T, Outin H. Intensive care unit-acquired weakness: risk factors and prevention. Crit Care Med. 2009;37(10 Suppl):S309–15.PubMedCrossRef de Jonghe B, Lacherade JC, Sharshar T, Outin H. Intensive care unit-acquired weakness: risk factors and prevention. Crit Care Med. 2009;37(10 Suppl):S309–15.PubMedCrossRef
20.
go back to reference Diaz MC, Ospina-Tascon GA, Salazar CB. Respiratory muscle dysfunction: a multicausal entity in the critically ill patient undergoing mechanical ventilation. Arch Bronconeumol. 2014;50(2):73–7.PubMedCrossRef Diaz MC, Ospina-Tascon GA, Salazar CB. Respiratory muscle dysfunction: a multicausal entity in the critically ill patient undergoing mechanical ventilation. Arch Bronconeumol. 2014;50(2):73–7.PubMedCrossRef
21.
go back to reference Winkelman C. Inactivity and inflammation in the critically ill patient. Crit Care Clin. 2007;23(1):21–34.PubMedCrossRef Winkelman C. Inactivity and inflammation in the critically ill patient. Crit Care Clin. 2007;23(1):21–34.PubMedCrossRef
22.
go back to reference Kasper CE, Talbot LA, Gaines JM. Skeletal muscle damage and recovery. AACN Clin Issues. 2002;13(2):237–47.PubMedCrossRef Kasper CE, Talbot LA, Gaines JM. Skeletal muscle damage and recovery. AACN Clin Issues. 2002;13(2):237–47.PubMedCrossRef
23.
go back to reference Topp R, Ditmyer M, King K, Doherty K, Hornyak J 3rd. The effect of bed rest and potential of prehabilitation on patients in the intensive care unit. AACN Clin Issues. 2002;13(2):263–76.PubMedCrossRef Topp R, Ditmyer M, King K, Doherty K, Hornyak J 3rd. The effect of bed rest and potential of prehabilitation on patients in the intensive care unit. AACN Clin Issues. 2002;13(2):263–76.PubMedCrossRef
24.
go back to reference Nordon-Craft A, Moss M, Quan D, Schenkman M. Intensive care unit-acquired weakness: implications for physical therapist management. Phys Ther. 2012;92(12):1494–506.PubMedPubMedCentralCrossRef Nordon-Craft A, Moss M, Quan D, Schenkman M. Intensive care unit-acquired weakness: implications for physical therapist management. Phys Ther. 2012;92(12):1494–506.PubMedPubMedCentralCrossRef
25.
go back to reference Swallow EB, Gosker HR, Ward KA, Moore AJ, Dayer MJ, Hopkinson NS, Schols AM, Moxham J, Polkey MI. A novel technique for nonvolitional assessment of quadriceps muscle endurance in humans. J Appl Physiol. 2007;103(3):739–46.PubMedCrossRef Swallow EB, Gosker HR, Ward KA, Moore AJ, Dayer MJ, Hopkinson NS, Schols AM, Moxham J, Polkey MI. A novel technique for nonvolitional assessment of quadriceps muscle endurance in humans. J Appl Physiol. 2007;103(3):739–46.PubMedCrossRef
26.
go back to reference Hansen RD, Williamson DA, Finnegan TP, Lloyd BD, Grady JN, Diamond TH, Smith EU, Stavrinos TM, Thompson MW, Gwinn TH, Allen BJ, Smerdely PI, Diwan AD, Singh NA, Singh MA. Estimation of thigh muscle cross-sectional area by dual-energy X-ray absorptiometry in frail elderly patients. Am J Clin Nutr. 2007;86(4):952–8.PubMed Hansen RD, Williamson DA, Finnegan TP, Lloyd BD, Grady JN, Diamond TH, Smith EU, Stavrinos TM, Thompson MW, Gwinn TH, Allen BJ, Smerdely PI, Diwan AD, Singh NA, Singh MA. Estimation of thigh muscle cross-sectional area by dual-energy X-ray absorptiometry in frail elderly patients. Am J Clin Nutr. 2007;86(4):952–8.PubMed
27.
go back to reference Seymour JM, Ward K, Sidhu PS, Puthucheary Z, Steier J, Jolley CJ, Rafferty G, Polkey MI, Moxham J. Ultrasound measurement of rectus femoris cross-sectional area and the relationship with quadriceps strength in COPD. Thorax. 2009;64(5):418–23.PubMedCrossRef Seymour JM, Ward K, Sidhu PS, Puthucheary Z, Steier J, Jolley CJ, Rafferty G, Polkey MI, Moxham J. Ultrasound measurement of rectus femoris cross-sectional area and the relationship with quadriceps strength in COPD. Thorax. 2009;64(5):418–23.PubMedCrossRef
28.
go back to reference e Lima KM, da Matta TT, de Oliveira LF. Reliability of the rectus femoris muscle cross-sectional area measurements by ultrasonography. Clin Physiol Funct Imaging. 2012;32(3):221–6.PubMedCrossRef e Lima KM, da Matta TT, de Oliveira LF. Reliability of the rectus femoris muscle cross-sectional area measurements by ultrasonography. Clin Physiol Funct Imaging. 2012;32(3):221–6.PubMedCrossRef
29.
go back to reference Cartwright MS, Kwayisi G, Griffin LP, Sarwal A, Walker FO, Harris JM, Berry MJ, Chahal PS, Morris PE. Quantitative neuromuscular ultrasound in the intensive care unit. Muscle Nerve. 2013;47(2):255–9.PubMedCrossRef Cartwright MS, Kwayisi G, Griffin LP, Sarwal A, Walker FO, Harris JM, Berry MJ, Chahal PS, Morris PE. Quantitative neuromuscular ultrasound in the intensive care unit. Muscle Nerve. 2013;47(2):255–9.PubMedCrossRef
30.
go back to reference Basso F, Berdin G, Virzi GM, Mason G, Piccinni P, Day S, Cruz DN, Wjewodzka M, Giuliani A, Brendolan A, Ronco C. Fluid management in the intensive care unit: bioelectrical impedance vector analysis as a tool to assess hydration status and optimal fluid balance in critically ill patients. Blood Purif. 2013;36(3–4):192–9.PubMedCrossRef Basso F, Berdin G, Virzi GM, Mason G, Piccinni P, Day S, Cruz DN, Wjewodzka M, Giuliani A, Brendolan A, Ronco C. Fluid management in the intensive care unit: bioelectrical impedance vector analysis as a tool to assess hydration status and optimal fluid balance in critically ill patients. Blood Purif. 2013;36(3–4):192–9.PubMedCrossRef
31.
go back to reference Robert S, Zarowitz BJ, Hyzy R, Eichenhorn M, Peterson EL, Popovich J Jr. Bioelectrical impedance assessment of nutritional status in critically ill patients. Am J Clin Nutr. 1993;57(6):840–4.PubMed Robert S, Zarowitz BJ, Hyzy R, Eichenhorn M, Peterson EL, Popovich J Jr. Bioelectrical impedance assessment of nutritional status in critically ill patients. Am J Clin Nutr. 1993;57(6):840–4.PubMed
32.
go back to reference Faisy C, Rabbat A, Kouchakji B, Laaban JP. Bioelectrical impedance analysis in estimating nutritional status and outcome of patients with chronic obstructive pulmonary disease and acute respiratory failure. Intensive Care Med. 2000;26(5):518–25.PubMedCrossRef Faisy C, Rabbat A, Kouchakji B, Laaban JP. Bioelectrical impedance analysis in estimating nutritional status and outcome of patients with chronic obstructive pulmonary disease and acute respiratory failure. Intensive Care Med. 2000;26(5):518–25.PubMedCrossRef
33.
go back to reference Gordon SE, Lake JA, Westerkamp CM, Thomson DM. Does AMP-activated protein kinase negatively mediate aged fast-twitch skeletal muscle mass? Exerc Sport Sci Rev. 2008;36(4):179–86.PubMedPubMedCentralCrossRef Gordon SE, Lake JA, Westerkamp CM, Thomson DM. Does AMP-activated protein kinase negatively mediate aged fast-twitch skeletal muscle mass? Exerc Sport Sci Rev. 2008;36(4):179–86.PubMedPubMedCentralCrossRef
34.
go back to reference Roth E. Amino acid and protein metabolism in critically ill patients. Infusionstherapie und klinische Ernahrung. 1985;12(6):270–80.PubMed Roth E. Amino acid and protein metabolism in critically ill patients. Infusionstherapie und klinische Ernahrung. 1985;12(6):270–80.PubMed
35.
go back to reference Klaude M, Mori M, Tjader I, Gustafsson T, Wernerman J, Rooyackers O. Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis. Clin Sci. 2012;122(3):133–42.PubMedCrossRef Klaude M, Mori M, Tjader I, Gustafsson T, Wernerman J, Rooyackers O. Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis. Clin Sci. 2012;122(3):133–42.PubMedCrossRef
37.
38.
go back to reference Glass DJ. Skeletal muscle hypertrophy and atrophy signaling pathways. Int J Biochem Cell Biol. 2005;37(10):1974–84.PubMedCrossRef Glass DJ. Skeletal muscle hypertrophy and atrophy signaling pathways. Int J Biochem Cell Biol. 2005;37(10):1974–84.PubMedCrossRef
39.
41.
go back to reference Mitch WE, Hu Z, Lee SW, Du J. Strategies for suppressing muscle atrophy in chronic kidney disease: mechanisms activating distinct proteolytic systems. J Renal Nutr. 2005;15(1):23–7.CrossRef Mitch WE, Hu Z, Lee SW, Du J. Strategies for suppressing muscle atrophy in chronic kidney disease: mechanisms activating distinct proteolytic systems. J Renal Nutr. 2005;15(1):23–7.CrossRef
42.
go back to reference Tagerud S, Libelius R. Lysosomes in skeletal muscle following denervation. Time course of horseradish peroxidase uptake and increase of lysosomal enzymes. Cell Tissue Res. 1984;236(1):73–9.PubMedCrossRef Tagerud S, Libelius R. Lysosomes in skeletal muscle following denervation. Time course of horseradish peroxidase uptake and increase of lysosomal enzymes. Cell Tissue Res. 1984;236(1):73–9.PubMedCrossRef
43.
go back to reference Weijs PJ, Wischmeyer PE. Optimizing energy and protein balance in the ICU. Curr Opin Clin Nutr Metab Care. 2013;16(2):194–201.PubMedCrossRef Weijs PJ, Wischmeyer PE. Optimizing energy and protein balance in the ICU. Curr Opin Clin Nutr Metab Care. 2013;16(2):194–201.PubMedCrossRef
44.
go back to reference Weijs PJ, Stapel SN, de Groot SD, Driessen RH, de Jong E, Girbes AR, Strack van Schijndel RJ, Beishuizen A. Optimal protein and energy nutrition decreases mortality in mechanically ventilated, critically ill patients: a prospective observational cohort study. J Parenter Enteral Nutr. 2012;36(1):60–8.CrossRef Weijs PJ, Stapel SN, de Groot SD, Driessen RH, de Jong E, Girbes AR, Strack van Schijndel RJ, Beishuizen A. Optimal protein and energy nutrition decreases mortality in mechanically ventilated, critically ill patients: a prospective observational cohort study. J Parenter Enteral Nutr. 2012;36(1):60–8.CrossRef
45.
go back to reference Allingstrup MJ, Esmailzadeh N, Wilkens Knudsen A, Espersen K, Hartvig Jensen T, Wiis J, Perner A, Kondrup J. Provision of protein and energy in relation to measured requirements in intensive care patients. Clin Nutr. 2012;31(4):462–8.PubMedCrossRef Allingstrup MJ, Esmailzadeh N, Wilkens Knudsen A, Espersen K, Hartvig Jensen T, Wiis J, Perner A, Kondrup J. Provision of protein and energy in relation to measured requirements in intensive care patients. Clin Nutr. 2012;31(4):462–8.PubMedCrossRef
46.
go back to reference McClave SA, Martindale RG, Vanek VW, McCarthy M, Roberts P, Taylor B, Ochoa JB, Napolitano L, Cresci G. Guidelines for the provision and assessment of nutrition support therapy in the adult critically Ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (ASPEN). J Parenter Enter Nutr. 2009;33(3):277–316.CrossRef McClave SA, Martindale RG, Vanek VW, McCarthy M, Roberts P, Taylor B, Ochoa JB, Napolitano L, Cresci G. Guidelines for the provision and assessment of nutrition support therapy in the adult critically Ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (ASPEN). J Parenter Enter Nutr. 2009;33(3):277–316.CrossRef
47.
go back to reference Hoffer LJ, Bistrian BR. Appropriate protein provision in critical illness: a systematic and narrative review. Am J Clin Nutr. 2012;96(3):591–600.PubMedCrossRef Hoffer LJ, Bistrian BR. Appropriate protein provision in critical illness: a systematic and narrative review. Am J Clin Nutr. 2012;96(3):591–600.PubMedCrossRef
48.
go back to reference Singer P, Berger MM, Van den Berghe G, Biolo G, Calder P, Forbes A, Griffiths R, Kreyman G, Leverve X, Pichard C. ESPEN Guidelines on Parenteral Nutrition: intensive care. Clin Nutr. 2009;28(4):387–400.PubMedCrossRef Singer P, Berger MM, Van den Berghe G, Biolo G, Calder P, Forbes A, Griffiths R, Kreyman G, Leverve X, Pichard C. ESPEN Guidelines on Parenteral Nutrition: intensive care. Clin Nutr. 2009;28(4):387–400.PubMedCrossRef
49.
go back to reference Jolliet P, Pichard C, Biolo G, Chiolero R, Grimble G, Leverve X, Nitenberg G, Novak I, Planas M, Preiser JC, Roth E, Schols AM, Wernerman J. Enteral nutrition in intensive care patients: a practical approach. Working group on nutrition and metabolism, ESICM. European Society of Intensive Care Medicine. Intensive Care Med. 1998;24(8):848–59.PubMedCrossRef Jolliet P, Pichard C, Biolo G, Chiolero R, Grimble G, Leverve X, Nitenberg G, Novak I, Planas M, Preiser JC, Roth E, Schols AM, Wernerman J. Enteral nutrition in intensive care patients: a practical approach. Working group on nutrition and metabolism, ESICM. European Society of Intensive Care Medicine. Intensive Care Med. 1998;24(8):848–59.PubMedCrossRef
50.
go back to reference Mesejo A, Sanchez Alvarez C, Arboleda Sanchez JA, Metabolism, Nutrition Working Group of the Spanish Society of Intensive Care M, Coronary u. Guidelines for specialized nutritional and metabolic support in the critically-ill patient: update. Consensus SEMICYUC-SENPE: obese patient. Nutr Hosp. 2011;26(Suppl 2):54–8.PubMed Mesejo A, Sanchez Alvarez C, Arboleda Sanchez JA, Metabolism, Nutrition Working Group of the Spanish Society of Intensive Care M, Coronary u. Guidelines for specialized nutritional and metabolic support in the critically-ill patient: update. Consensus SEMICYUC-SENPE: obese patient. Nutr Hosp. 2011;26(Suppl 2):54–8.PubMed
51.
go back to reference Hoffer LJ, Bistrian BR. What is the best nutritional support for critically ill patients? Hepatobil Surg Nutr. 2014;3(4):172–4. Hoffer LJ, Bistrian BR. What is the best nutritional support for critically ill patients? Hepatobil Surg Nutr. 2014;3(4):172–4.
52.
go back to reference Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, McMurdo ME, Mets T, Seal C, Wijers SL, Ceda GP, De Vito G, Donders G, Drey M, Greig C, Holmbäck U, Narici M, McPhee J, Poggiogalle E, Power D, Scafoglieri A, Schultz R, Sieber CC, Cederholm T. Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc. 2015;16(9):740–7.PubMedCrossRef Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, McMurdo ME, Mets T, Seal C, Wijers SL, Ceda GP, De Vito G, Donders G, Drey M, Greig C, Holmbäck U, Narici M, McPhee J, Poggiogalle E, Power D, Scafoglieri A, Schultz R, Sieber CC, Cederholm T. Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc. 2015;16(9):740–7.PubMedCrossRef
53.
go back to reference Rondanelli M, Klersy C, Terracol G, Talluri J, Maugeri R, Guido D, Faliva MA, Solerte BS, Fioravanti M, Lukaski H, Perna S. Whey protein, amino acids, and vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly. Am J Clin Nutr. 2016;103(3):830–40.PubMedCrossRef Rondanelli M, Klersy C, Terracol G, Talluri J, Maugeri R, Guido D, Faliva MA, Solerte BS, Fioravanti M, Lukaski H, Perna S. Whey protein, amino acids, and vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly. Am J Clin Nutr. 2016;103(3):830–40.PubMedCrossRef
55.
go back to reference Ceglia L, Harris SS. Vitamin D and its role in skeletal muscle. Calcif Tissue Int. 2013;92(2):151–62.PubMedCrossRef Ceglia L, Harris SS. Vitamin D and its role in skeletal muscle. Calcif Tissue Int. 2013;92(2):151–62.PubMedCrossRef
56.
go back to reference Braun AB, Gibbons FK, Litonjua AA, Giovannucci E, Christopher KB. Low serum 25-hydroxyvitamin D at critical care initiation is associated with increased mortality. Crit Care Med. 2012;40(1):63–72.PubMedPubMedCentralCrossRef Braun AB, Gibbons FK, Litonjua AA, Giovannucci E, Christopher KB. Low serum 25-hydroxyvitamin D at critical care initiation is associated with increased mortality. Crit Care Med. 2012;40(1):63–72.PubMedPubMedCentralCrossRef
57.
go back to reference Higgins DM, Wischmeyer PE, Queensland KM, Sillau SH, Sufit AJ, Heyland DK. Relationship of vitamin D deficiency to clinical outcomes in critically ill patients. J Parenter Enter Nutr. 2012;36(6):713–20.CrossRef Higgins DM, Wischmeyer PE, Queensland KM, Sillau SH, Sufit AJ, Heyland DK. Relationship of vitamin D deficiency to clinical outcomes in critically ill patients. J Parenter Enter Nutr. 2012;36(6):713–20.CrossRef
58.
go back to reference McKinney JD, Bailey BA, Garrett LH, Peiris P, Manning T, Peiris AN. Relationship between vitamin D status and ICU outcomes in veterans. J Am Med Dir Assoc. 2011;12(3):208–11.PubMedCrossRef McKinney JD, Bailey BA, Garrett LH, Peiris P, Manning T, Peiris AN. Relationship between vitamin D status and ICU outcomes in veterans. J Am Med Dir Assoc. 2011;12(3):208–11.PubMedCrossRef
59.
go back to reference Needham DM, Davidson J, Cohen H, Hopkins RO, Weinert C, Wunsch H, Zawistowski C, Bemis-Dougherty A, Berney SC, Bienvenu OJ, Brady SL, Brodsky MB, Denehy L, Elliott D, Flatley C, Harabin AL, Jones C, Louis D, Meltzer W, Muldoon SR, Palmer JB, Perme C, Robinson M, Schmidt DM, Scruth E, Spill GR, Storey CP, Render M, Votto J, Harvey MA. Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders’ conference. Crit Care Med. 2012;40(2):502–9.PubMedCrossRef Needham DM, Davidson J, Cohen H, Hopkins RO, Weinert C, Wunsch H, Zawistowski C, Bemis-Dougherty A, Berney SC, Bienvenu OJ, Brady SL, Brodsky MB, Denehy L, Elliott D, Flatley C, Harabin AL, Jones C, Louis D, Meltzer W, Muldoon SR, Palmer JB, Perme C, Robinson M, Schmidt DM, Scruth E, Spill GR, Storey CP, Render M, Votto J, Harvey MA. Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders’ conference. Crit Care Med. 2012;40(2):502–9.PubMedCrossRef
60.
go back to reference Kayambu G, Boots R, Paratz J. Physical therapy for the critically ill in the ICU: a systematic review and meta-analysis. Crit Care Med. 2013;41(6):1543–54.PubMedCrossRef Kayambu G, Boots R, Paratz J. Physical therapy for the critically ill in the ICU: a systematic review and meta-analysis. Crit Care Med. 2013;41(6):1543–54.PubMedCrossRef
61.
go back to reference Amidei C. Mobilisation in critical care: a concept analysis. Intensive Crit Care Nurs. 2012;28(2):73–81.PubMedCrossRef Amidei C. Mobilisation in critical care: a concept analysis. Intensive Crit Care Nurs. 2012;28(2):73–81.PubMedCrossRef
62.
go back to reference Parry SM, Berney S, Granger CL, Koopman R, El-Ansary D, Denehy L. Electrical muscle stimulation in the intensive care setting: a systematic review. Crit Care Med. 2013;41(10):2406–18.PubMedCrossRef Parry SM, Berney S, Granger CL, Koopman R, El-Ansary D, Denehy L. Electrical muscle stimulation in the intensive care setting: a systematic review. Crit Care Med. 2013;41(10):2406–18.PubMedCrossRef
Metadata
Title
Sarcopenia in critically ill patients
Authors
Muhammet C. Kizilarslanoglu
Mehmet E. Kuyumcu
Yusuf Yesil
Meltem Halil
Publication date
01-10-2016
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 5/2016
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-016-2211-4

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