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Journal of Anesthesia
Published in: Journal of Anesthesia 2/2015

01-04-2015 | Review Article

Implications of recent accumulating knowledge about endothelial glycocalyx on anesthetic management

Author: Ghada M. N. Bashandy

Published in: Journal of Anesthesia | Issue 2/2015

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Abstract

The endothelial glycocalyx is a labile, fine structure coating the luminal membrane of intact healthy vascular endothelium. For many decades, no physiologic importance was linked to this structure. It is crucial for vascular barrier function. There has been an immense interest in recent years for studying this important structure, and research is needed to disclose more information about it. Perioperative damage of the glycocalyx has been demonstrated, and is linked with morbidity and even mortality in surgical patients. Research on the glycocalyx should change many of the current perioperative management guidelines, and focusing on its protection is plausible. The present article reviews what we already know about the glycocalyx and how this knowledge has changed anesthesiologist perspectives.
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Metadata
Title
Implications of recent accumulating knowledge about endothelial glycocalyx on anesthetic management
Author
Ghada M. N. Bashandy
Publication date
01-04-2015
Publisher
Springer Japan
Published in
Journal of Anesthesia / Issue 2/2015
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-014-1887-6

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