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Published in: Journal of Hepato-Biliary-Pancreatic Sciences 1/2007

01-01-2007

Antimicrobial therapy for acute cholangitis: Tokyo Guidelines

Authors: Atsushi Tanaka, Tadahiro Takada, Yoshifumi Kawarada, Yuji Nimura, Masahiro Yoshida, Fumihiko Miura, Masahiko Hirota, Keita Wada, Toshihiko Mayumi, Harumi Gomi, Joseph S. Solomkin, Steven M. Strasberg, Henry A. Pitt, Jacques Belghiti, Eduardo de Santibanes, Robert Padbury, Miin-Fu Chen, Giulio Belli, Chen-Guo Ker, Serafin C. Hilvano, Sheung-Tat Fan, Kui-Hin Liau

Published in: Journal of Hepato-Biliary-Pancreatic Sciences | Issue 1/2007

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Abstract

Antimicrobial agents should be administered to all patients with suspected acute cholangitis as a priority as soon as possible. Bile cultures should be performed at the earliest opportunity. The important factors which should be considered in selecting antimicrobial therapy include the agent’s activity against potentially infecting bacteria, the severity of the cholangitis, the presence or absence of renal and hepatic diseases, the patient’s recent history of antimicrobial therapy, and any recent culture results, if available. Biliary penetration of the microbial agents should also be considered in the selection of antimicrobials, but activity against the infecting isolates is of greatest importance. If the causative organisms are identified, empirically chosen antimicrobial drugs should be replaced by narrower-spectrum antimicrobial agents, the most appropriate for the species and the site of the infection.
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Metadata
Title
Antimicrobial therapy for acute cholangitis: Tokyo Guidelines
Authors
Atsushi Tanaka
Tadahiro Takada
Yoshifumi Kawarada
Yuji Nimura
Masahiro Yoshida
Fumihiko Miura
Masahiko Hirota
Keita Wada
Toshihiko Mayumi
Harumi Gomi
Joseph S. Solomkin
Steven M. Strasberg
Henry A. Pitt
Jacques Belghiti
Eduardo de Santibanes
Robert Padbury
Miin-Fu Chen
Giulio Belli
Chen-Guo Ker
Serafin C. Hilvano
Sheung-Tat Fan
Kui-Hin Liau
Publication date
01-01-2007
Publisher
Springer-Verlag
Published in
Journal of Hepato-Biliary-Pancreatic Sciences / Issue 1/2007
Print ISSN: 1868-6974
Electronic ISSN: 1868-6982
DOI
https://doi.org/10.1007/s00534-006-1157-6

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