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Supportive Care in Cancer
Published in: Supportive Care in Cancer 4/2013

01-04-2013 | Original Article

Periodontal care in patients undergoing radiotherapy for head and neck cancer

Authors: Audrey Cristina Bueno, Raquel Conceição Ferreira, Flávia Isabela Barbosa, Bruno Correia Jham, Cláudia Silami Magalhães, Allyson Nogueira Moreira

Published in: Supportive Care in Cancer | Issue 4/2013

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Abstract

Purpose

The aim of this study was to evaluate periodontal changes after periodontal treatment and control in patients with malignant tumors of the upper aerodigestive tract who were submitted to radiotherapy with or without chemotherapy.

Methods

We included all patients attending the Oncology Clinic of the Federal University of Minas Gerais, School of Dentistry. Clinical periodontal parameters obtained by a single calibrated examiner were evaluated at baseline, 10 days after radiotherapy, and 180 days after radiotherapy. Patients were grouped into healthy or periodontally diseased individuals. All patients received oral hygiene instructions, and the diseased patients received periodontal therapy at baseline. Comparisons between the groups were performed via the McNemar and Wilcoxon tests using SPSS v. 17.0.

Results

A total of 28 patients were examined at baseline, of which 27 were examined 10 days after radiotherapy and 25 were examined 180 days after radiotherapy. The prevalence of periodontal disease at baseline was 67.9 % and did not decrease over time (p = 1.0). There was a significant reduction in probing depth (PD), plaque index (PI), and bleeding on probing between baseline and follow-up, which was not observed in the attachment level (AL).

Conclusions

Periodontal therapy was effective in reducing PI and improving periodontal status, as evidenced by the decreases in PD and the maintenance of AL.
Literature
1.
2.
Langendijk JA (2007) New developments in radiotherapy of head and neck cancer: higher precision with less patient discomfort? Radiother Oncol 85:1–6PubMedCrossRef
3.
Haddad R, Annino D, Tishler RB (2008) Multidisciplinary approach to cancer treatment: focus on head and neck cancer. Dent Clin N Am 52:1–17PubMedCrossRef
4.
Hong CHL, Napeñas JL, Hodgson BD et al (2010) A systematic review of dental disease in patients undergoing cancer therapy. Support Care Cancer 18:1007–1021PubMedCrossRef
5.
Fischer DJ, Epstein JB (2008) Management of patients who have undergone head and neck cancer therapy. Dent Clin N Am 52:39–60PubMedCrossRef
6.
Lerman MA, Laudanbach J, Marty FM, Baden LR, Treister NS (2008) Management of oral infections in cancer patients. Dent Clin N Am 52:129–153PubMedCrossRef
7.
Bensadoun RJ, Patton LL, Lalla RV, Epstein JB (2011) Oropharyngeal candidiasis in head and neck cancer patients treated with radiation: update 2011. Support Care Cancer 19:737–744PubMedCrossRef
8.
Joyston-Bechal S (1992) Prevention of dental diseases following radiotherapy and chemotherapy. Int Dent J 42:47–53PubMed
9.
Marx RE (1983) Osteoradionecrosis: a new concept of its pathophysiology. J Oral Maxillofac Surg 41:283–288PubMedCrossRef
10.
Marx RE, Johnson RP (1987) Studies in the radiobiology of osteoradionecrosis and their clinical significance. Oral Surg Oral Med Oral Pathol 64:379–390PubMedCrossRef
11.
Schuurhuis JM, Stokman MA, Roodenburg JLN et al (2011) Efficacy of routine pre-radiation dental screening and dental follow-up in head and neck oncology patients on intermediate and late radiation effects. A retrospective evaluation. Radiother Oncol 101(3):403–409PubMedCrossRef
12.
Epstein JB, Stevenson-Moore P (2001) Periodontal disease and periodontal management in patients with cancer. Oral Oncol 37:613–619PubMedCrossRef
13.
Markitziu A, Zafiropoulos G, Tsalikis L, Cohen L (1992) Gingival health and salivary function in head and neck irradiated patients. Oral Surg Oral Med Oral Pathol 73:427–433PubMedCrossRef
14.
Epstein JB, Lunn R, Le N, Moore PS (1998) Periodontal attachment loss in patients after head and neck radiation therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86:673–677PubMedCrossRef
15.
Marques MAC, Dib LL (2004) Periodontal changes in patients undergoing radiotherapy. J Periodontol 75:1178–1187PubMedCrossRef
16.
Specht L (2002) Oral complications in the head and neck radiation patient—introduction and scope of the problem. Support Care Cancer 10:36–39PubMedCrossRef
17.
Barker GJ, Epstein JB, Williams KB (2005) Current practice and knowledge of oral care for cancer patients: a survey of supportive health care providers. Support Care Cancer 13:32–41PubMedCrossRef
18.
Kashiwazaki H, Matsushita T, Sugita J et al (2012) Professional oral health care reduces oral mucositis and febrile neutropenia in patients treated with allogeneic bone marrow transplantation. Support Care Cancer 20:367–373PubMedCrossRef
19.
Röing M, Hirsch JM, Holmström I (2006) Ways of understanding the encounter with head and neck cancer patients in the hospital dental team—a phenomenographic study. Support Care Cancer 14:1046–1054PubMedCrossRef
20.
Epstein JB, Parker IR, Epstein MS et al (2007) A survey of National Cancer Institute-designated comprehensive cancer centers’ oral health supportive care practices and resources in the USA. Support Care Cancer 15:357–362PubMedCrossRef
21.
Sato J, Gotto J, Harahashi A et al (2011) Oral health care reduces the risk of postoperative surgical site infection in inpatients with oral Squamous cell carcinoma. Support Care Cancer 19:409–416PubMedCrossRef
22.
McGuire DB, Correa MEP, Johnson J, Wienandts P (2006) The role of basic oral care and good clinical practice principles in the management of oral mucositis. Support Care Cancer 14:541–547PubMedCrossRef
23.
Patel SG, Shah JP (2005) TNM staging of cancers of the head and neck: striving for uniformity among diversity. CA Cancer J Clin 55:242–258PubMedCrossRef
24.
Ainamo J, Bay I (1975) Problems and proposals for recording gingivitis and plaque. Int Dent J 25(4):229–235PubMed
25.
Armitage GC (2004) The complete periodontal examination. Periodontol 2000(34):22–33CrossRef
26.
27.
Landis RJ, Koch GC (1997) The measurement of observer agreement for categorical data. Biometrics 33:159–174CrossRef
28.
Page RC, Eke PI (2007) Case definitions for use in population-based surveillance of periodontitis. J Periodontol 78:1397–1399CrossRef
29.
Kornman KS (2008) Mapping the pathogenesis of periodontitis: a new look. J Periodontol 79:1560–1568PubMedCrossRef
30.
Jereczek-Fossa BA, Orecchia R (2002) Radiotherapy-induced mandibular bone complications. Cancer Treat Rev 28:65–74PubMedCrossRef
31.
Peterson DE, Doerr W, Hovan A et al (2010) Osteoradionecrosis in cancer patients: the evidence base for treatment-dependent frequency, current management strategies, and future studies. Support Care Cancer 18:1089–1098PubMedCrossRef
32.
Badersten A, Nilvéus R, Egelberg J (1981) Effect of nonsurgical periodontal therapy I: moderately advanced periodontitis. J Clin Periodontol 8:57–72PubMedCrossRef
33.
Badersten A, Nilvéus R, Egelberg J (1984) Effect of nonsurgical periodontal therapy II: severely advanced periodontitis. J Clin Periodontol 11:63–76PubMedCrossRef
34.
MacNabb H, Mombelli A, Lang NP (1992) Supragingival cleaning 3 times a week. The microbiological effects in moderately deep pockets. J Clin Periodontol 19:348–356CrossRef
35.
Dahlén G, Lindhe J, Sato K, Hanamura H, Okamoto H (1992) The effect of supragingival plaque control on the subgingival microbiota in subjects with periodontal disease. J Clin Periodontol 19:802–809PubMedCrossRef
36.
Nogueira MA, Luna DG, Bianchini H, Alonso C, Piovano S (2000) Effect of supragingival plaque control on subgingival microflora and gingivo-periodontal tissues. Acta Odontol Latinoam 13(2):73–86 (in Spanish)
37.
Kielbassa AM, Hinkelbein W, Hellwing E, Meyer-Lückel H (2006) Radiation-related damage to dentition. Lancet Oncol 7:326–335PubMedCrossRef
38.
Brennan MT, Woo SB, Lockhart PB (2008) Dental treatment planning and management in patient who has cancer. Dent Clin N Am 52:19–37PubMedCrossRef
Metadata
Title
Periodontal care in patients undergoing radiotherapy for head and neck cancer
Authors
Audrey Cristina Bueno
Raquel Conceição Ferreira
Flávia Isabela Barbosa
Bruno Correia Jham
Cláudia Silami Magalhães
Allyson Nogueira Moreira
Publication date
01-04-2013
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 4/2013
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-012-1614-5

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