Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Supportive Care in Cancer
Published in: Supportive Care in Cancer 6/2006

01-06-2006 | Review Article

The role of basic oral care and good clinical practice principles in the management of oral mucositis

Authors: Deborah B. McGuire, Maria Elvira P. Correa, Judith Johnson, Patricia Wienandts

Published in: Supportive Care in Cancer | Issue 6/2006

Login to get access

Abstract

Background

The Basic Oral Care Group is one of eight subcommittees functioning within the Mucositis Study Group Guidelines Panel of the Multinational Association of Supportive Care in Cancer and International Society for Oral Oncology (MASCC/ISOO). The Basic Oral Care Group, comprised of the four authors of this paper, represented the disciplines of nursing (DBM, JJ), dentistry (MEPC), and pediatric dentistry (PW). This group reviewed research and clinical literature to update the original 2004 Mucositis Management Guidelines in the areas of basic oral care, bland rinses, protocols and education, and good clinical practices such as pain management, oral assessment, oral care, and dental care.

Materials and methods

Over 100 articles published between 2000 and 2005 were identified, and 32 of these were useful for the analysis. Each article was rated by at least two authors using a structured rating form and systematic determination of levels of evidence, based on the American Society of Clinical Oncology criteria. Discussion at the 2005 MASCC/ISOO Geneva preconference meeting of the Guidelines Panel resulted in the development of consensus on the interpretation of the literature.

Results

Based on the literature and on Panel discussions, a revision of the original guidelines for protocols and education was produced by the group, and they developed a set of recommendations related to good clinical practices.

Conclusions

Although research remains scanty for components of basic oral care, bland rinses, protocols, and education, the original 2004 guidelines with the help of newer literature from 2000 to 2005 and expert consensus among the Guidelines Panel enabled the development of useful clinical practice guidelines for managing oral mucositis in patients receiving cancer treatment with radiation and/or chemotherapy.
Literature
1.
Cella D, Pulliam J, Fuchs H, Miller C, Hurd C, Wingard JR, Sonis ST, Martin PJ, Giles F (2003) Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy. Cancer 98:406–412PubMedCrossRef
2.
Cerchietti LCA, Navigante AH, Bonomi MR, Zaderajko MA, Menendez PR, Pogany CE, Roth BMC (2002) Effect of topical morphine for mucositis-associated pain following concomitant chemoradiotherapy for head and neck carcinoma. Cancer 95:2230–2236PubMedCrossRef
3.
Chalmers J, Johnson V (2004) Evidence-based protocol: oral hygiene care for functionally dependent and cognitively impaired older adults. J Gerontol Nurs 30(11):5–12PubMed
4.
Chan CWH, Chang AM, Molassiotis A, Lee IYM, Lee GCT (2003) Oral complications in Chinese cancer patients undergoing chemotherapy. Support Care Cancer 11:48–55PubMed
5.
Chen C-F, Wang R-H, Cheng S-N, Chang Y-C (2004) Assessment of chemotherapy-induced oral complications in children with cancer. J Pediatr Oncol Nurs 21:33–39PubMedCrossRef
6.
Cheng KKF (2004) Children’s acceptance and tolerance of chlorhexidine and benzydamine oral rinses in the treatment of chemotherapy-induced oropharyngeal mucositis. Eur J Oncol Nurs 8:341–349PubMedCrossRef
7.
Cheng KKF, Chang AM (2003) Palliation of oral mucositis symptoms in pediatric patients treated with cancer chemotherapy. Cancer Nurs 26:476–484PubMedCrossRef
8.
Cheng KKF, Molassiotis A, Chang AM, Wai WC, Cheung SS (2001) Evaluation of an oral care protocol intervention in the prevention of chemotherapy-induced oral mucositis in paediatric cancer patients. Eur J Cancer 37:2056–2063PubMedCrossRef
9.
Cheng KKF, Chang AM, Yuen MP (2004) Prevention of oral mucositis in paediatric patients treated with chemotherapy: a randomised crossover trial comparing two protocols of oral care. Eur J Cancer 40:1208–1216PubMedCrossRef
10.
Clarkson JE, Worthington HV, Eden OB (2003) Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev (3):CD000978 (review)
11.
Costa EMMdeB, Fernandez MZ, Quindere LB, deSouza LB, Pinto LP (2003) Evaluation of an oral preventive protocol in children with acute lymphoblastic leukemia. Pesqui Odontol Bras 17(2):147–150PubMedCrossRef
12.
Dahlin C (2004) Oral complications at the end of life. Am J Nurs 104(7):40–47PubMed
13.
Daniel BT, Damato KL, Johnson J (2004) Educational issues in oral care. Semin Oncol Nurs 20:48–52PubMedCrossRef
14.
Dodd MJ, Miaskowski C, Greenspan D, MacPhail L, Shih A, Shiba G, Facione N, Paul SM (2003) Radiation-induced mucositis: a randomized clinical trial of micronized sucralfate versus salt & soda mouthwashes. Cancer Invest 21:21–33PubMedCrossRef
15.
Epstein JB, Truelove EL, Oien H, Allison C, Le ND, Epstein MS (2001) Oral topical doxepin rinse: analgesic effect in patients with oral mucosal pain due to cancer or cancer therapy. Oral Oncol 37:632–637PubMedCrossRef
16.
Fulton JF, Middleton GJ, McPhail JT (2002) Management of oral complications. Semin Oncol Nurs 18:28–35PubMedCrossRef
17.
Glenny AM, Gibson F, Auld E, Coulson S, Clarkson JE, Craig JV, Eden OB, Worthington HV, Pizer B on behalf of the UKCCSG-PONF Mouth Care Group (2004) A survey of current practice with regard to oral care for children being treated for cancer. Eur J Cancer 40:1217–1224PubMedCrossRef
18.
Hadorn DC, Baker D, Hodges JS, Hicks N (1996) Rating the quality of evidence for clinical practice guidelines. J Clin Epidemiol 49:749–754PubMedCrossRef
19.
Hancock PJ, Epstein JB, Sadler GR (2003) Oral and dental management related to radiation therapy for head and neck cancer. J Can Dent Assoc 69:585–590PubMed
20.
Harris DJ, Knobf MT (2004) Assessing and managing chemotherapy-induced mucositis pain. Clin J Oncol Nurs 8:622–628PubMedCrossRef
21.
Honnor A, Law A (2002) Mouth care in cancer nursing: using an audit to change practice. Br J Nurs 11:1087–1096PubMed
22.
Kennedy HF, Morrison D, Tomlinson D, Gibson BES, Bagg J, Gemmell CG (2002) Gingivitis and toothbrushes: potential roles in viridans streptococcal bacteraemia. J Infect 46(1):67–70CrossRef
23.
Kwong KKF (2004) Prevention and treatment of oropharyngeal mucositis following cancer therapy: are there new approaches? Cancer Nurs 27:183–205PubMedCrossRef
24.
McGuire DB (2003) Barriers and strategies in implementation of oral care standards for cancer patients. Support Care Cancer 11:435–441PubMedCrossRef
25.
Mead GM (2002) Management of oral mucositis associated with cancer chemotherapy. Lancet 359:815–816PubMedCrossRef
26.
Melkos AB, Massenkeil G, Arnold R, Reichart PA (2003) Dental treatment prior to stem cell transplantation and its influence on the posttransplantation outcome. Clin Oral Invest 7:113–115CrossRef
27.
Rubenstein EB, Peterson DE, Schubert M, Keefe D, McGuire D, Epstein J, Elting LS, Fox PC, Cooksley C, Sonis ST (2004) Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis. Cancer 100(9 Suppl):2026–2046PubMedCrossRef
28.
Sadler GR, Stoudt A, Fullerton JT, Oberle-Edwards LK, Nguyen Q, Epstein JB (2003) Managing the oral sequelae of cancer therapy. Medsurg Nurs 12(1):28–36PubMed
29.
Schiodt M, Hermund NU (2002) Management of oral disease prior to radiation therapy. Support Care Cancer 10:40–43PubMedCrossRef
30.
Scully C, Epstein J, Sonis S (2004) Oral mucositis: a challenging complication of radiotherapy, chemotherapy, and radiochemotherapy. Part 2: diagnosis and management of mucositis. Head Neck 26(1):77–84PubMedCrossRef
31.
Shih A, Miaskowski C, Dodd MJ, Stotts NA, MacPhail L (2002) A review of the current treatments for radiation-induced oral mucositis in patients with head and neck cancer. Oncol Nurs Forum 29:1063–1080PubMedCrossRef
32.
Somerfield MR, Padberg JJ, Pfister DG, Bennett CL, Recht A, Smith TJ, Weeks JC, Winn RJ, Durant JR (2000) ASCO clinical practice guidelines: process, progress, pitfalls, and prospects. Class Pap Curr Comments 4(4):881–886
33.
Turhal NS, Erdal S, Karacay S (2000) Efficacy of treatment to relieve mucositis-induced discomfort. Support Care Cancer 8:55–58PubMed
34.
Vered M, Dayan D, Buchner A (2004) Treatment modalities for chemo- and radiotherapy-induced oral mucositis—critical analysis and practical guidelines. J Israel Dent Assoc 21:19–28
35.
Wohlschlaeger A (2004) Prevention and treatment of mucositis: a guide for nurses. J Pediatr Oncol Nurs 21:281–287PubMedCrossRef
Metadata
Title
The role of basic oral care and good clinical practice principles in the management of oral mucositis
Authors
Deborah B. McGuire
Maria Elvira P. Correa
Judith Johnson
Patricia Wienandts
Publication date
01-06-2006
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 6/2006
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-006-0051-8

Other articles of this Issue 6/2006

Supportive Care in Cancer 6/2006 Go to the issue

Review Article

Developing evidence-based guidelines for management of alimentary mucositis: process and pitfalls

Original Article

Promulgation of guidelines for mucositis management: educating health care professionals and patients

Review Article

Antimicrobials, mucosal coating agents, anesthetics, analgesics, and nutritional supplements for alimentary tract mucositis

Forthcoming Meetings

Forthcoming Meetings

Review Article

Epidemiology of treatment-associated mucosal injury after treatment with newer regimens for lymphoma, breast, lung, or colorectal cancer

Review Article

Amifostine in the management of radiation-induced and chemo-induced mucositis
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Watch now

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine
Image Credits