Skip to main content
Top
Published in: Supportive Care in Cancer 4/2010

01-04-2010 | Original Article

“It makes you feel so full of life” LiveWell, a feasibility study of a personalised lifestyle programme for colorectal cancer survivors

Authors: Annie S. Anderson, Stephen Caswell, Mary Wells, Robert J. C. Steele, Susan MacAskill

Published in: Supportive Care in Cancer | Issue 4/2010

Login to get access

Abstract

Goals

The acceptability and feasibility of a 3-month personalised lifestyle (diet, exercise and weight management) intervention in overweight adults who had completed curative treatment for colorectal cancer were assessed by qualitative interviews, quality-of-life questionnaires and subjective and objective measures of diet and activity.

Main results

Over a 4-month period, 28 of 37 (75%) patients met the inclusion criteria and 20 (71%) of the eligible patients agreed to participate in the study and 18 (90%) completed the 3-month study. Reported adherence related to tailored advice, personalised feedback and family support. Reported barriers included time following surgery, fatigue, having a stoma or chronic diarrhoea and conflicting advice from clinicians. A weight change of −1.2 (±4.4) kg was achieved overall and −4.1 (±3.7) kg in the ten who had lost weight.

Conclusions

Colorectal cancer survivors will participate in a lifestyle change initiative. Interventions should be personalised to suit abilities, provide feedback on personal goals and encourage social support. Intervention timing and attaining greater support from clinicians should be explored prior to the development of an efficacy trial.
Literature
1.
go back to reference Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ (2003) Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 348:625–638CrossRef Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ (2003) Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 348:625–638CrossRef
2.
go back to reference Davey Smith G, Shipley MJ, Batty GD, Morris JN, Marmot M (2000) Physical activity and cause-specific mortality in the Whitehall study. Public Health 114(5):308–315CrossRefPubMed Davey Smith G, Shipley MJ, Batty GD, Morris JN, Marmot M (2000) Physical activity and cause-specific mortality in the Whitehall study. Public Health 114(5):308–315CrossRefPubMed
3.
go back to reference Giovannucci E (1995) Ascherio A Rimm EB Colditz GA Stampfer MJ Willett WC Physical activity, obesity, and risk for colon cancer and adenoma in men. Ann Intern Med 122(5):327–334PubMed Giovannucci E (1995) Ascherio A Rimm EB Colditz GA Stampfer MJ Willett WC Physical activity, obesity, and risk for colon cancer and adenoma in men. Ann Intern Med 122(5):327–334PubMed
4.
go back to reference Haydon AM, Macinnis RJ, English DR, Giles GG (2006) Effect of physical activity and body size on survival after diagnosis with colorectal cancer. Gut 55:62–67CrossRefPubMed Haydon AM, Macinnis RJ, English DR, Giles GG (2006) Effect of physical activity and body size on survival after diagnosis with colorectal cancer. Gut 55:62–67CrossRefPubMed
5.
go back to reference Meyerhardt JA, Niedzwiecki D, Hollis D et al (2007) Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer. JAMA 298(7):754–764CrossRefPubMed Meyerhardt JA, Niedzwiecki D, Hollis D et al (2007) Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer. JAMA 298(7):754–764CrossRefPubMed
6.
go back to reference Meyerhardt JA, Catalano PJ, Haller DG, Mayer RJ, Benson AB III, Macdonald JS, Fuchs CS (2003) Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma. Cancer 98(3):484–495CrossRefPubMed Meyerhardt JA, Catalano PJ, Haller DG, Mayer RJ, Benson AB III, Macdonald JS, Fuchs CS (2003) Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma. Cancer 98(3):484–495CrossRefPubMed
7.
go back to reference Meyerhardt JA, Hesletine D, Niedzwiecki D et al (2005) The impact of physical activity on patients with stage III colon cancer: findings from Intergroup trial CALGB 89803. J Clin Oncol 23(16S):3534 Meyerhardt JA, Hesletine D, Niedzwiecki D et al (2005) The impact of physical activity on patients with stage III colon cancer: findings from Intergroup trial CALGB 89803. J Clin Oncol 23(16S):3534
8.
go back to reference Avenell A, Broon J, Brown TJ et al (2004) Systematic review of the long term effects and economic consequences of treatments for obesity and implications of health improvements. Health Technol Assess 8(21):1–455 Avenell A, Broon J, Brown TJ et al (2004) Systematic review of the long term effects and economic consequences of treatments for obesity and implications of health improvements. Health Technol Assess 8(21):1–455
9.
go back to reference Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Eng J Med 346(6):393–403CrossRef Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Eng J Med 346(6):393–403CrossRef
10.
go back to reference Tuomilehto J, Lindstrom J, Eriksson JG et al (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Eng J Med 344(18):1343–1350CrossRef Tuomilehto J, Lindstrom J, Eriksson JG et al (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Eng J Med 344(18):1343–1350CrossRef
11.
go back to reference Torjesen JS, Birkeland KI, Anderssen KI et al (1997) Lifestyle changes may reverse development of the insulin resistance syndrome: the Oslo Diet and Exercise Study. Diabetes Care 20(1):26–31CrossRefPubMed Torjesen JS, Birkeland KI, Anderssen KI et al (1997) Lifestyle changes may reverse development of the insulin resistance syndrome: the Oslo Diet and Exercise Study. Diabetes Care 20(1):26–31CrossRefPubMed
12.
go back to reference Anderson AS, Ferguson CS, Barton KL, Steele RJC (2006) Implementing lifestyle interventions to reduce chronic disease risk: lessons from diabetes prevention trials. Proc Nutr Soc 65:55A Anderson AS, Ferguson CS, Barton KL, Steele RJC (2006) Implementing lifestyle interventions to reduce chronic disease risk: lessons from diabetes prevention trials. Proc Nutr Soc 65:55A
13.
go back to reference Campbell M, Fitzpatrick R, Haines A et al (2000) Framework for design and evaluation of complex interventions to improve health. BMJ 321:694–696CrossRefPubMed Campbell M, Fitzpatrick R, Haines A et al (2000) Framework for design and evaluation of complex interventions to improve health. BMJ 321:694–696CrossRefPubMed
14.
go back to reference Roe L, Strong C, Whiteside C, Neil A, Mant D (1994) Dietary intervention in primary care: validity of the DINE method for diet assessment. Fam Pract 11:375–381CrossRefPubMed Roe L, Strong C, Whiteside C, Neil A, Mant D (1994) Dietary intervention in primary care: validity of the DINE method for diet assessment. Fam Pract 11:375–381CrossRefPubMed
16.
go back to reference Ruta DA, Garratt AM, Leng M, Russell IT, MacDonald LM (1994) A new approach to measurement of quality of life. Med Care 3(11):1109–1126CrossRef Ruta DA, Garratt AM, Leng M, Russell IT, MacDonald LM (1994) A new approach to measurement of quality of life. Med Care 3(11):1109–1126CrossRef
17.
go back to reference Ness AR, Khaw KT, Bingham S, Day NE (1998) Plasma Vitamin C: what does it measure? Pub Health Nutrition 2(1):51–54 Ness AR, Khaw KT, Bingham S, Day NE (1998) Plasma Vitamin C: what does it measure? Pub Health Nutrition 2(1):51–54
18.
go back to reference Craig K (2007) Enjoy project. Evaluation of a lifestyle intervention programme for colorectal cancer patients in Tayside. MPH thesis, University of Dundee Craig K (2007) Enjoy project. Evaluation of a lifestyle intervention programme for colorectal cancer patients in Tayside. MPH thesis, University of Dundee
19.
go back to reference Anderson AS et al (2004) Evidence based dietary behaviour strategies to reduce cancer risk. In: Sancho-Garnier H (ed) Evidence-based cancer prevention strategies for NGOs. UICC, Geneva Anderson AS et al (2004) Evidence based dietary behaviour strategies to reduce cancer risk. In: Sancho-Garnier H (ed) Evidence-based cancer prevention strategies for NGOs. UICC, Geneva
20.
go back to reference Anderson AS (2000) How to implement dietary changes to prevent the development of metabolic syndrome. Br J Nutrition 83:S165–S168CrossRef Anderson AS (2000) How to implement dietary changes to prevent the development of metabolic syndrome. Br J Nutrition 83:S165–S168CrossRef
21.
go back to reference Miles MB, Huberman A (1994) Qualitative data analysis: an expanded sourcebook. Sage, Thousand Oaks Miles MB, Huberman A (1994) Qualitative data analysis: an expanded sourcebook. Sage, Thousand Oaks
22.
go back to reference Pan X et al (1997) Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance: the Da Qing IGT and Diabetes Study. Diabetes Care 20(4):537–544CrossRefPubMed Pan X et al (1997) Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance: the Da Qing IGT and Diabetes Study. Diabetes Care 20(4):537–544CrossRefPubMed
23.
go back to reference Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M (2008) Developing and evaluating complex interventions: the new Medical Research Council guidance. Br Med J 337:1655CrossRef Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M (2008) Developing and evaluating complex interventions: the new Medical Research Council guidance. Br Med J 337:1655CrossRef
25.
go back to reference Hawe P, Shiell A, Riley T, Gold L (2004) Methods for exploring implementation variation and local context within a cluster randomised community intervention trial. J Epidemiol Community Health 58(9):788–793CrossRefPubMed Hawe P, Shiell A, Riley T, Gold L (2004) Methods for exploring implementation variation and local context within a cluster randomised community intervention trial. J Epidemiol Community Health 58(9):788–793CrossRefPubMed
26.
go back to reference Wells EM (2007) Behind the scenes of randomised trials of complex interventions: Insiders reveal the importance of context. Ph.D. Thesis, University of Dundee Wells EM (2007) Behind the scenes of randomised trials of complex interventions: Insiders reveal the importance of context. Ph.D. Thesis, University of Dundee
Metadata
Title
“It makes you feel so full of life” LiveWell, a feasibility study of a personalised lifestyle programme for colorectal cancer survivors
Authors
Annie S. Anderson
Stephen Caswell
Mary Wells
Robert J. C. Steele
Susan MacAskill
Publication date
01-04-2010
Publisher
Springer-Verlag
Published in
Supportive Care in Cancer / Issue 4/2010
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-009-0677-4

Other articles of this Issue 4/2010

Supportive Care in Cancer 4/2010 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine