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Supportive Care in Cancer

Published in:

01-04-2009 | Original Article

Evaluation of a mobile phone-based, advanced symptom management system (ASyMS^©) in the management of chemotherapy-related toxicity

Authors: N. Kearney, L. McCann, J. Norrie, L. Taylor, P. Gray, M. McGee-Lennon, M. Sage, M. Miller, R. Maguire

Published in: Supportive Care in Cancer | Issue 4/2009

Abstract

Objectives

To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS^©) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand–foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer.

Design

A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial.

Setting

Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals.

Participants

One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy.

Interventions

A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS^©).

Main outcome measures

Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand–foot syndrome and diarrhoea).

Results

There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio = 2.29, 95%CI = 1.04 to 5.05, P = 0.040) and reports of hand–foot syndrome were on average lower in the control group (odds ratio control/intervention = 0.39, 95%CI = 0.17 to 0.92, P = 0.031).

Conclusion

The study demonstrates that ASyMS^© can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.

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Title: Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity
Authors: N. Kearney
L. McCann
J. Norrie
L. Taylor
P. Gray
M. McGee-Lennon
M. Sage
M. Miller
R. Maguire
Publication date: 01-04-2009
Publisher: Springer-Verlag
Published in: Supportive Care in Cancer / Issue 4/2009
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-008-0515-0

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Abstract

Objectives

Design

Setting

Participants

Interventions

Main outcome measures

Results

Conclusion

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