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Published in:

01-07-2016 | Review

Kidney donation after circulatory death: current evidence and opportunities for pediatric recipients

Authors: Matko Marlais, Chris Callaghan, Stephen D. Marks

Published in: Pediatric Nephrology | Issue 7/2016

Abstract

Organ donation after circulatory death (DCD) has experienced a revival worldwide over the past 20 years, and is now widely practiced for kidney transplantation. Some previous concerns about these organs such as the high incidence of delayed graft function have been alleviated through evidence from adult studies. There are now a number of large adult cohorts reporting favorable 5-year outcomes for DCD kidney transplants, comparable to kidneys donated after brain death (DBD). This has resulted in a marked increase in the use of DCD kidneys for adult recipients in some countries and an increase in the overall number of kidney transplants. In contrast, the uptake of DCD kidneys for pediatric recipients is still low and concerns still exist over the longer-term outcomes of DCD organs. In view of the data from adult practice and the poor outcomes for children who stay on dialysis, DCD kidney transplantation should be offered as an option for children on the kidney transplant waiting list.

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Title: Kidney donation after circulatory death: current evidence and opportunities for pediatric recipients
Authors: Matko Marlais
Chris Callaghan
Stephen D. Marks
Publication date: 01-07-2016
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Nephrology / Issue 7/2016
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-015-3175-6

At a glance: The STEP trials

Springer Medicine

Kidney donation after circulatory death: current evidence and opportunities for pediatric recipients

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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