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Published in: Pediatric Nephrology 1/2013

01-01-2013 | Educational Review

Cystic kidney diseases: many ways to form a cyst

Authors: Hannah Loftus, Albert C. M. Ong

Published in: Pediatric Nephrology | Issue 1/2013

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Abstract

Renal cysts are a common radiological finding in both adults and children. They occur in a variety of conditions, and the clinical presentation, management, and prognosis varies widely. In this article, we discuss the major causes of renal cysts in children and adults with a particular focus on the most common genetic forms. Many cystoproteins have been localized to the cilia centrosome complex (CCC). We consider the evidence for a universal ‘cilia hypothesis’ for cyst formation and the evidence for non-ciliary proteins in cyst formation.
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Metadata
Title
Cystic kidney diseases: many ways to form a cyst
Authors
Hannah Loftus
Albert C. M. Ong
Publication date
01-01-2013
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 1/2013
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-012-2221-x

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