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Published in: Pediatric Nephrology 1/2013

01-01-2013 | Review

Drug-related problem in children with chronic kidney disease

Authors: Norkasihan Ibrahim, Ian CK Wong, Susan Patey, Stephen Tomlin, Manish D Sinha, Yogini Jani

Published in: Pediatric Nephrology | Issue 1/2013

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Abstract

Drug therapies in the management of chronic kidney disease (CKD) are complex and specialised and have a high potential for drug-related problem (DRP). In adult CKD populations, the identification and resolution of DRP has been shown to have beneficial effects on disease management, adherence and knowledge of treatment, patient’s quality of life, hospitalisation rate and length of stay and cost to the healthcare system. The focus of this article is the review of published studies on DRP in children with CKD. There is a lack of information on the epidemiology of DRP in this patient group, and research in this area is therefore needed to better understand and manage DRP in children with CKD.
Literature
2.
go back to reference National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases (2010) United States Renal Data System, USRDS 2010 annual data report: atlas of chronic kidney disease and end-stage renal disease in the United States. Available at: http://www.usrds.org/atlas.htm. Accessed 27 Mar 2011 National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases (2010) United States Renal Data System, USRDS 2010 annual data report: atlas of chronic kidney disease and end-stage renal disease in the United States. Available at: http://​www.​usrds.​org/​atlas.​htm. Accessed 27 Mar 2011
3.
go back to reference Harambat J, van Stralen KJ, Kim JJ, Tizard EJ (2011) Epidemiology of chronic kidney disease in children. Pediatr Nephrol 27:363–373PubMedCrossRef Harambat J, van Stralen KJ, Kim JJ, Tizard EJ (2011) Epidemiology of chronic kidney disease in children. Pediatr Nephrol 27:363–373PubMedCrossRef
4.
go back to reference Warady BA, Chadha V (2007) Chronic kidney disease in children: the global perspective. Pediatr Nephrol 22:1999–2009PubMedCrossRef Warady BA, Chadha V (2007) Chronic kidney disease in children: the global perspective. Pediatr Nephrol 22:1999–2009PubMedCrossRef
5.
go back to reference Kaplan B, Mason NA, Shimp LA, Ascione FJ (1994) Chronic hemodialysis patients. Part I: characterization and drug-related problems. Ann Pharmacother 28:316–319PubMed Kaplan B, Mason NA, Shimp LA, Ascione FJ (1994) Chronic hemodialysis patients. Part I: characterization and drug-related problems. Ann Pharmacother 28:316–319PubMed
6.
go back to reference Manley HJ, Drayer DK, Muther RS (2003) Medication-related problem type and appearance rate in ambulatory hemodialysis patients. BMC Nephrol 4:1–7CrossRef Manley HJ, Drayer DK, Muther RS (2003) Medication-related problem type and appearance rate in ambulatory hemodialysis patients. BMC Nephrol 4:1–7CrossRef
7.
go back to reference Cardone KE, Bacchus S, Assimon MM, Pai AB, Manley HJ (2010) Medication-related problems in CKD. Adv Chronic Kidney Dis 17:404–412PubMedCrossRef Cardone KE, Bacchus S, Assimon MM, Pai AB, Manley HJ (2010) Medication-related problems in CKD. Adv Chronic Kidney Dis 17:404–412PubMedCrossRef
8.
go back to reference Grabe DW, Low CL, Bailie GR, Eisele G (1997) Evaluation of drug-related problems in an outpatient hemodialysis unit and the impact of a clinical pharmacist. Clin Nephrol 47:117–121PubMed Grabe DW, Low CL, Bailie GR, Eisele G (1997) Evaluation of drug-related problems in an outpatient hemodialysis unit and the impact of a clinical pharmacist. Clin Nephrol 47:117–121PubMed
9.
go back to reference Kaplan B, Mason NA, Shimp LA, Ascione FJ (1994) Chronic hemodialysis patients. Part II: reducing drug-related problems through application of the focused drug therapy review program. Ann Pharmacother 28:320–324PubMed Kaplan B, Mason NA, Shimp LA, Ascione FJ (1994) Chronic hemodialysis patients. Part II: reducing drug-related problems through application of the focused drug therapy review program. Ann Pharmacother 28:320–324PubMed
10.
go back to reference Tozawa M, Iseki K, Iseki C, Oshiro S, Higashiuesato Y, Yamazato M, Tomiyama N, Tana T, Takishita S (2002) Analysis of drug prescription in chronic haemodialysis patients. Nephrol Dial Transplant 17:1819–1824PubMedCrossRef Tozawa M, Iseki K, Iseki C, Oshiro S, Higashiuesato Y, Yamazato M, Tomiyama N, Tana T, Takishita S (2002) Analysis of drug prescription in chronic haemodialysis patients. Nephrol Dial Transplant 17:1819–1824PubMedCrossRef
11.
go back to reference Mirkov S (2009) Implementation of a pharmacist medication review clinic for haemodialysis patients. N Z Med J 122:25–37PubMed Mirkov S (2009) Implementation of a pharmacist medication review clinic for haemodialysis patients. N Z Med J 122:25–37PubMed
12.
go back to reference Sathvik BS, Mangasuli S, Narahari MG, Gurudev KC, Parthasarathi G (2007) Medication knowledge of hemodialysis patients and influence of clinical pharmacist provided education on their knowledge. Indian J Pharm Sci 69:232–239CrossRef Sathvik BS, Mangasuli S, Narahari MG, Gurudev KC, Parthasarathi G (2007) Medication knowledge of hemodialysis patients and influence of clinical pharmacist provided education on their knowledge. Indian J Pharm Sci 69:232–239CrossRef
13.
go back to reference Pai AB, Boyd A, Chavez A, Manley HJ (2009) Health-related quality of life is maintained in hemodialysis patients receiving pharmaceutical care: a 2-year randomized, controlled study. Hemodial Int 13:72–79PubMedCrossRef Pai AB, Boyd A, Chavez A, Manley HJ (2009) Health-related quality of life is maintained in hemodialysis patients receiving pharmaceutical care: a 2-year randomized, controlled study. Hemodial Int 13:72–79PubMedCrossRef
14.
go back to reference Pai AB, Boyd A, Depczynski J, Chavez IM, Khan N, Manley H (2009) Reduced drug use and hospitalization rates in patients undergoing hemodialysis who received pharmaceutical care: a 2-year, randomized, controlled study. Pharmacotherapy 29:1433–1440PubMedCrossRef Pai AB, Boyd A, Depczynski J, Chavez IM, Khan N, Manley H (2009) Reduced drug use and hospitalization rates in patients undergoing hemodialysis who received pharmaceutical care: a 2-year, randomized, controlled study. Pharmacotherapy 29:1433–1440PubMedCrossRef
15.
go back to reference Manley HJ, Carroll CA (2002) The clinical and economic impact of pharmaceutical care in end-stage renal disease patients. Semin Dial 15:45–49PubMedCrossRef Manley HJ, Carroll CA (2002) The clinical and economic impact of pharmaceutical care in end-stage renal disease patients. Semin Dial 15:45–49PubMedCrossRef
17.
go back to reference Frommer M, Rubin G, Lyle D (1992) The NSW health outcomes program. N S W Public Health Bull 3:135CrossRef Frommer M, Rubin G, Lyle D (1992) The NSW health outcomes program. N S W Public Health Bull 3:135CrossRef
18.
go back to reference Strand LM, Morley PC, Cipolle RJ, Ramsey R, Lamsam GD (1990) Drug-related problems: their structure and function. Drug Intel Clin Pharm 24:1093–1097 Strand LM, Morley PC, Cipolle RJ, Ramsey R, Lamsam GD (1990) Drug-related problems: their structure and function. Drug Intel Clin Pharm 24:1093–1097
19.
go back to reference Leape LL, Brennan TA, Laird N, Lawthers AG, Localio AR, Barnes BA, Hebert L, Newhouse JP, Weiler PC, Hiatt H (1991) The nature of adverse events in hospitalized patients. Results of the Harvard medical practice study II. N Engl J Med 324:377–384PubMedCrossRef Leape LL, Brennan TA, Laird N, Lawthers AG, Localio AR, Barnes BA, Hebert L, Newhouse JP, Weiler PC, Hiatt H (1991) The nature of adverse events in hospitalized patients. Results of the Harvard medical practice study II. N Engl J Med 324:377–384PubMedCrossRef
20.
go back to reference Edwards IR, Aronson JK (2000) Adverse drug reactions: definitions, diagnosis, and management. Lancet 356:1255–1259PubMedCrossRef Edwards IR, Aronson JK (2000) Adverse drug reactions: definitions, diagnosis, and management. Lancet 356:1255–1259PubMedCrossRef
21.
go back to reference Morimoto T, Gandhi TK, Seger AC, Hsieh TC, Bates DW (2004) Adverse drug events and medication errors: detection and classification methods. Qual Saf Health Care 13:306–314PubMedCrossRef Morimoto T, Gandhi TK, Seger AC, Hsieh TC, Bates DW (2004) Adverse drug events and medication errors: detection and classification methods. Qual Saf Health Care 13:306–314PubMedCrossRef
22.
go back to reference So TY, Layton JB, Bozik K, Farrington E, Gipson PE, Gibson K, Primack W, Conley W 3rd, Gipson DS, Ferris M (2011) Cognitive pharmacy services at a pediatric nephrology and hypertension clinic. Renal Fail 33:19–25CrossRef So TY, Layton JB, Bozik K, Farrington E, Gipson PE, Gibson K, Primack W, Conley W 3rd, Gipson DS, Ferris M (2011) Cognitive pharmacy services at a pediatric nephrology and hypertension clinic. Renal Fail 33:19–25CrossRef
23.
go back to reference Jani YH, Ghaleb MA, Marks SD, Cope J, Barber N, Wong IC (2008) Electronic prescribing reduced prescribing errors in a pediatric renal outpatient clinic. J Pediatr 152:214–218PubMedCrossRef Jani YH, Ghaleb MA, Marks SD, Cope J, Barber N, Wong IC (2008) Electronic prescribing reduced prescribing errors in a pediatric renal outpatient clinic. J Pediatr 152:214–218PubMedCrossRef
24.
go back to reference Perrier-Cornet E, Prot-Labarthe S, Bourdon O, Brion F (2010) Report of pharmaceutical care in a nephrology paediatric care unit. Pharm World Sci 32:259–259 Perrier-Cornet E, Prot-Labarthe S, Bourdon O, Brion F (2010) Report of pharmaceutical care in a nephrology paediatric care unit. Pharm World Sci 32:259–259
25.
go back to reference Lincenberg J, Lerner G, Robin A, Layfield S, Macdonald N, Fleischmann L, Gruskin A (1986) Improving compliance in adolescent CAPD patients. Am J Kidney Dis 8:A13–A13 Lincenberg J, Lerner G, Robin A, Layfield S, Macdonald N, Fleischmann L, Gruskin A (1986) Improving compliance in adolescent CAPD patients. Am J Kidney Dis 8:A13–A13
26.
go back to reference Atiyeh BA, Dabbagh SS, Gruskin AB (1996) Evaluation of renal function during childhood. Pediatr Rev 17:175–180PubMedCrossRef Atiyeh BA, Dabbagh SS, Gruskin AB (1996) Evaluation of renal function during childhood. Pediatr Rev 17:175–180PubMedCrossRef
27.
go back to reference Brandt JR, Wong CS, Hanrahan JD, Qualls C, McAfee N, Watkins SL (2006) Estimating absolute glomerular filtration rate in children. Pediatr Nephrol 21:1865–1872PubMedCrossRef Brandt JR, Wong CS, Hanrahan JD, Qualls C, McAfee N, Watkins SL (2006) Estimating absolute glomerular filtration rate in children. Pediatr Nephrol 21:1865–1872PubMedCrossRef
28.
go back to reference Hogg RJ, Furth S, Lemley KV, Portman R, Schwartz GJ, Coresh J, Balk E, Lau J, Levin A, Kausz AT, Eknoyan G, Levey AS (2003) National kidney foundation's kidney disease outcomes quality initiative clinical practice guidelines for chronic kidney disease in children and adolescents: evaluation, classification, and stratification. Pediatrics 111:1416–1421PubMedCrossRef Hogg RJ, Furth S, Lemley KV, Portman R, Schwartz GJ, Coresh J, Balk E, Lau J, Levin A, Kausz AT, Eknoyan G, Levey AS (2003) National kidney foundation's kidney disease outcomes quality initiative clinical practice guidelines for chronic kidney disease in children and adolescents: evaluation, classification, and stratification. Pediatrics 111:1416–1421PubMedCrossRef
29.
go back to reference Kimland E, Bergman U, Lindemalm S, Böttiger Y (2007) Drug related problems and off-label drug treatment in children as seen at a drug information centre. Eur J Pediatr 166:527–532PubMedCrossRef Kimland E, Bergman U, Lindemalm S, Böttiger Y (2007) Drug related problems and off-label drug treatment in children as seen at a drug information centre. Eur J Pediatr 166:527–532PubMedCrossRef
30.
go back to reference Impicciatore P, Choonara I, Clarkson A, Provasi D, Pandolfini C, Bonati M (2001) Incidence of adverse drug reactions in paediatric in/out-patients: a systematic review and meta-analysis of prospective studies. Br J Clin Pharmacol 52:77–83PubMedCrossRef Impicciatore P, Choonara I, Clarkson A, Provasi D, Pandolfini C, Bonati M (2001) Incidence of adverse drug reactions in paediatric in/out-patients: a systematic review and meta-analysis of prospective studies. Br J Clin Pharmacol 52:77–83PubMedCrossRef
31.
go back to reference Churchwell MD, Mueller BA (2007) Selected pharmacokinetic issues in patients with chronic kidney disease. Blood Purif 25:133–138PubMedCrossRef Churchwell MD, Mueller BA (2007) Selected pharmacokinetic issues in patients with chronic kidney disease. Blood Purif 25:133–138PubMedCrossRef
32.
go back to reference Chisholm-Burns MA, Spivey CA, Rehfeld R, Zawaideh M, Roe DJ, Gruessner R (2009) Immunosuppressant therapy adherence and graft failure among pediatric renal transplant recipients. Am J Transplant 9:2497–2504PubMedCrossRef Chisholm-Burns MA, Spivey CA, Rehfeld R, Zawaideh M, Roe DJ, Gruessner R (2009) Immunosuppressant therapy adherence and graft failure among pediatric renal transplant recipients. Am J Transplant 9:2497–2504PubMedCrossRef
33.
go back to reference Chisolm MA, Kwong WJ, Spivey CA (2007) Associations of characteristics of renal transplant recipients with clinician’s perceptions of adherence to immunosuppressant therapy. Transplantation 84:1145–1150CrossRef Chisolm MA, Kwong WJ, Spivey CA (2007) Associations of characteristics of renal transplant recipients with clinician’s perceptions of adherence to immunosuppressant therapy. Transplantation 84:1145–1150CrossRef
34.
Metadata
Title
Drug-related problem in children with chronic kidney disease
Authors
Norkasihan Ibrahim
Ian CK Wong
Susan Patey
Stephen Tomlin
Manish D Sinha
Yogini Jani
Publication date
01-01-2013
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 1/2013
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-012-2149-1

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