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Pediatric Nephrology
Published in: Pediatric Nephrology 2/2011

01-02-2011 | Original Article

Behavioral disorders and low quality of life in children and adolescents with chronic kidney disease

Authors: Renata C. Marciano, Cristina M. Bouissou Soares, José Silvério S. Diniz, Eleonora M. Lima, Jose Maria P. Silva, Monica R. Canhestro, Andrea Gazzinelli, Carla Cristina D. Melo, Cristiane S. Dias, Ana Cristina Simões e Silva, Humberto Correa, Eduardo A. Oliveira

Published in: Pediatric Nephrology | Issue 2/2011

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Abstract

Recent years has seen an increasing interest in the quality of life (QOL) of children with chronic kidney disease (CKD). The objective of this cross-sectional study was to investigate the prevalence of behavioral disorders and to assess the health-related QOL (HRQOL) in 136 patients with CKD. To estimate the prevalence of behavior disorders and analyze HRQOL, we used the Strengths and Difficulties Questionnaire (SDQ) and Pediatric Inventory of Quality of Life (PedsQL) Core Scales as assessment tools for both the patients and caregivers. When compared to healthy controls, the CKD group had significantly lower scores in almost all PedsQL domains. After adjustment, only absence of religion/other religions remained significantly associated with a lower global HRQOL score [odds ratio (OR) 6.2, P = 0.009]. Among the parents, two factors remained significantly associated with a lower global HRQOL score: patients’ age >10 years (OR 5.4, P = 0.033) and absence of religion/other religions (OR  3.2, P = 0.038). The CKD group demonstrated a higher proportion of behavioral and emotional disorders in all SDQ domains. There was a negative correlation between the presence of behavior and emotional disorders and HRQOL score (r = −0.552, P < 0.001). Our findings suggest the importance of evaluating behavioral and social repercussions of CKD in order to improve the life quality of this pediatric population.
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Metadata
Title
Behavioral disorders and low quality of life in children and adolescents with chronic kidney disease
Authors
Renata C. Marciano
Cristina M. Bouissou Soares
José Silvério S. Diniz
Eleonora M. Lima
Jose Maria P. Silva
Monica R. Canhestro
Andrea Gazzinelli
Carla Cristina D. Melo
Cristiane S. Dias
Ana Cristina Simões e Silva
Humberto Correa
Eduardo A. Oliveira
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 2/2011
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-010-1683-y

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