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01-12-2010 | Review

Acute kidney injury: can we improve prognosis?

Authors: Christine W. Hsu, Jordan M. Symons

Published in: Pediatric Nephrology | Issue 12/2010

Abstract

The incidence of pediatric acute kidney injury (AKI) is increasing. AKI has been found to be independently associated with increased mortality, and current management options are limited in that they are mainly supportive. The use of various definitions of AKI can still be found in the literature, making it difficult to discern the epidemiology behind pediatric AKI. The use of a more uniform definition is a necessary first step to clarify AKI epidemiology and direct our research efforts, and it will ultimately improve prognosis. There is evidence that neonates and infants may be at higher risk for AKI than adults. However, the least amount of research is found for this youngest age group, and more focused efforts on this population are necessary. This paper reviews existing data on and definitions for pediatric AKI, general preventive and treatment strategies, as well as ongoing research efforts on AKI. We are hopeful that the prognosis of AKI will improve with collaboration on a multicenter, multinational scale in the form of prospective, long-term studies on pediatric AKI.

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Title: Acute kidney injury: can we improve prognosis?
Authors: Christine W. Hsu
Jordan M. Symons
Publication date: 01-12-2010
Publisher: Springer-Verlag
Published in: Pediatric Nephrology / Issue 12/2010
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-010-1508-z

At a glance: The STEP trials

Springer Medicine

Acute kidney injury: can we improve prognosis?

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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