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Intensive Care Medicine

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Open Access 01-12-2009 | Pediatric Brief Report

An assessment of acute kidney injury with modified RIFLE criteria in pediatric patients with severe burns

Authors: Tina Palmieri, Athina Lavrentieva, David Greenhalgh

Published in: Intensive Care Medicine | Issue 12/2009

Abstract

Objective

To apply the modified pediatric RIFLE criteria for severity of acute kidney injury (AKI) to pediatric burn ICU patients and to evaluate the overall incidence of AKI, risk factors for AKI and influence of AKI on outcome.

Design

Retrospective, descriptive cohort study.

Setting

10-bed burn PICU facility.

Patients

All consecutive patients with a burn injury of 10% or more of total body surface area percentage (TBSA, %) admitted during a 2 year period.

Measurements and results

Data of 123 patients were studied. The incidence of AKI was 45.5%. Patients with AKI tended to have higher mortality than those without AKI (p = 0.057). All nonsurvivors attained pRIFLE AKI by combination of serum creatinine and urine output criteria. Patients with a more severe form of AKI (Failure and Injury) as well as patients with late AKI had more episodes of sepsis as compared to patients with early AKI and the Risk category of AKI. Logistic regression analysis indicated that PRISM score and TBSA were the independent risk factors for acute kidney injury in pediatric burn patients; the presence of sepsis and septic shock were the independent risk factors for the Failure class of AKI.

Conclusion

We observed a high incidence of AKI in the burn PICU population. Sepsis seems to contribute to the development of the Failure class of AKI. Maximum Failure class of AKI is associated with high mortality.

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Title: An assessment of acute kidney injury with modified RIFLE criteria in pediatric patients with severe burns
Authors: Tina Palmieri
Athina Lavrentieva
David Greenhalgh
Publication date: 01-12-2009
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 12/2009
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-009-1638-6

At a glance: The STEP trials

Springer Medicine

An assessment of acute kidney injury with modified RIFLE criteria in pediatric patients with severe burns

Abstract

Objective

Design

Setting

Patients

Measurements and results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Design

Setting

Patients

Measurements and results

Conclusion

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