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Published in: Pediatric Nephrology 4/2010

01-04-2010 | Original Article

Etiology and treatment of growth retardation in children with chronic kidney disease and end-stage renal disease: a historical perspective

Author: Richard N. Fine

Published in: Pediatric Nephrology | Issue 4/2010

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Abstract

Dramatic changes have occurred in our understanding of the etiology of the growth retardation associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD) during the past 50 years. Significant interest has been focused on preventing and/or correcting the growth retardation because of the emergence of the dual therapeutic modalities of dialysis and renal transplantation to prolong the lives of infants, children, and adolescents afflicted with CKD and ESRD. These efforts have resulted in a significant improvement in the height Z-score over the past two decades of children with CKD and ESRD. This has had a salutary impact on the final adult height of such children which should hopefully lead to an enhanced quality of life in the future. This report addresses the progress that has been made in the management of growth retardation in the pediatric population with CKD and ESRD.
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Metadata
Title
Etiology and treatment of growth retardation in children with chronic kidney disease and end-stage renal disease: a historical perspective
Author
Richard N. Fine
Publication date
01-04-2010
Publisher
Springer-Verlag
Published in
Pediatric Nephrology / Issue 4/2010
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-009-1409-1

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