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Published in: Surgical Endoscopy 9/2019

01-09-2019 | 2018 EAES Oral

Is laparoscopic left adrenalectomy with the anterior submesocolic approach for Conn’s or Cushing’s syndrome equally safe and effective as the lateral and anterior ones?

Authors: Andrea Balla, Silvia Quaresima, Livia Palmieri, Monica Ortenzi, Emilia Sbardella, Giulia Puliani, Andrea M. Isidori, Mario Guerrieri, Alessandro M. Paganini

Published in: Surgical Endoscopy | Issue 9/2019

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Abstract

Background

The aim of the present study is to report and to compare the results of three different laparoscopic transperitoneal surgical approaches [lateral transperitoneal (LT), anterior transperitoneal (AT) and anterior transperitoneal submesocolic (ATS)] for the treatment of Conn’s and Cushing’s syndrome from left adrenal disease.

Methods

This study is a retrospective analysis of prospectively collected data. From 1994 to 2017, 535 laparoscopic adrenalectomies (LA) were performed. One hundred and sixty-four patients with Conn’s or Cushing’s syndrome underwent left LA. Patients were divided in three groups based on the approach: LT (Group A), AT (Group B) and ATS (Group C).

Results

The diagnosis was Conn’s and Cushing’s syndrome in 99 and 65 patients, respectively. LT was used in 13 cases, AT in 55 and ATS in 96. No significant differences in patient’s gender, age and BMI were observed. Mean operative time was 117.6 ± 33.7, 107.6 ± 40.3 and 96.2 ± 47.5 min for Groups A, B and C, respectively. Conversion to open surgery was observed in 4 Group C patients (4.1%). Morbidity occurred in 2 Group B (2%) and in 5 Group C patients (5.2%).

Conclusions

In case of Conn’s or Cushing’s syndrome, left LA with ATS approach is equally safe and effective as compared to the LT and AT approaches. Early control of the adrenal vein with minimal gland manipulation and limited surgical dissection are the major advantages of the submesocolic approach. Even if statistically significant differences are not observed, postoperative results are the same as those reported in the literature with other approaches.
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Metadata
Title
Is laparoscopic left adrenalectomy with the anterior submesocolic approach for Conn’s or Cushing’s syndrome equally safe and effective as the lateral and anterior ones?
Authors
Andrea Balla
Silvia Quaresima
Livia Palmieri
Monica Ortenzi
Emilia Sbardella
Giulia Puliani
Andrea M. Isidori
Mario Guerrieri
Alessandro M. Paganini
Publication date
01-09-2019
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 9/2019
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-018-6601-6

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