Skip to main content
Top
Published in: Surgical Endoscopy 6/2018

01-06-2018

Influence of antrum size on gastric emptying and weight-loss outcomes after laparoscopic sleeve gastrectomy (preliminary analysis of a randomized trial)

Authors: Meritxell Garay, Carmen Balagué, Carlos Rodríguez-Otero, Berta Gonzalo, Anna Domenech, Juan Carlos Pernas, Ignasi J. Gich, Inka Miñambres, Sonia Fernández-Ananín, Eduardo M. Targarona

Published in: Surgical Endoscopy | Issue 6/2018

Login to get access

Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) has increased in popularity in recent years as a definitive bariatric procedure. Despite its growing popularity worldwide, the surgical technique is not well standardized. There is a lack of evidence on the matter of the antrum size and its relation to gastric emptying and weight-loss outcomes. The aim of the study is to evaluate the influence of antrum size over gastric emptying and weight-loss outcomes.

Methods

Twenty-five patients were prospectively randomized according to the distance between the first firing and the pylorus: AR group (antrum resection—2 cm from the pylorus) and AP group (antrum preservation—5 cm from the pylorus). Gastric emptying (%GE) was evaluated by a gastric emptying scintigraphy before surgery, 2 months and 1 year after LSG. Antrum volume was measured using a MultiSlice CT Scan performed 2 months and 1 year after surgery. The percent of excess weight loss (%EWL) was calculated after 1 year follow-up.

Results

At 2 months after LSG the mean %GE was 69.7 ± 18 in the AR group and 72.8 ± 20 in the AP group (p = 0.69). At 1 year it was 66.5 ± 21 and 74.2 ± 16 in the AR and AP groups, respectively (p = 0.30). A significant accelerated gastric emptying was observed at 2 months (p = 0.025) and at 1 year (p = 0.013) in the AP group. Meanwhile in the AR group this increase was not significant (p = 0.12 at 2 months and p = 0.21 at 1 year). Differences regarding the %EWL between groups were no statistically significant (p = 0.74).

Conclusions

After LSG there is a global tendency to an accelerated gastric emptying, although only significant in the antrum preservation group; however, no differences were observed regarding the %EWL between groups after 1 year follow-up.
Literature
1.
go back to reference Shi X, Karmali S, Sharma AM, Birch DW (2010) A review of laparoscopic sleeve gastrectomy for morbid obesity. Obes Surg 20:1171–1177CrossRefPubMed Shi X, Karmali S, Sharma AM, Birch DW (2010) A review of laparoscopic sleeve gastrectomy for morbid obesity. Obes Surg 20:1171–1177CrossRefPubMed
2.
go back to reference Lee CM, Cirangle PT, Jossart GH (2007) Vertical gastrectomy for morbid obesity in 216 patients: report of two-year results. Surg Endosc 21:1810–1816CrossRefPubMed Lee CM, Cirangle PT, Jossart GH (2007) Vertical gastrectomy for morbid obesity in 216 patients: report of two-year results. Surg Endosc 21:1810–1816CrossRefPubMed
3.
go back to reference Papailou J, Albanopoulos K, Toutouzas KG, Tsigris C, Nikiteas N, Zografos G (2010) Morbid obesity and sleeve gastrectomy: how does it work? Obes Surg 20:1448–1455CrossRef Papailou J, Albanopoulos K, Toutouzas KG, Tsigris C, Nikiteas N, Zografos G (2010) Morbid obesity and sleeve gastrectomy: how does it work? Obes Surg 20:1448–1455CrossRef
4.
go back to reference Melissas J, Koukouraki S, Askoxylakis J, Stathaki M, Daskalakis M, Perisinakis K, Karkavitsas N (2007) Sleeve gastrectomy—a restrictive procedure? Obes Surg 17:57–62CrossRefPubMed Melissas J, Koukouraki S, Askoxylakis J, Stathaki M, Daskalakis M, Perisinakis K, Karkavitsas N (2007) Sleeve gastrectomy—a restrictive procedure? Obes Surg 17:57–62CrossRefPubMed
5.
go back to reference Braghetto I, Davanzo C, Korn O, Csendes A, Valladares H, Herrera E, Gonzalez P, Papapietro K (2009) Scintigraphic evaluation of gastric emptying on obese patients submitted to sleeve gastrectomy compared to normal subjects. Obes Surg 19:1515–1521CrossRefPubMed Braghetto I, Davanzo C, Korn O, Csendes A, Valladares H, Herrera E, Gonzalez P, Papapietro K (2009) Scintigraphic evaluation of gastric emptying on obese patients submitted to sleeve gastrectomy compared to normal subjects. Obes Surg 19:1515–1521CrossRefPubMed
6.
go back to reference Bernstine H, Yehoshua RT, Groshar D, Beglaibter N, Shikora S, Rosenthal RJ, Rubin M (2009) Gastric emptying is nor affected by sleeve gastrectomy–scintigraphic evaluation of gastric emptying after sleeve gastrectomy without removal of the gastric antrum. Obes Surg 19:293–298CrossRefPubMed Bernstine H, Yehoshua RT, Groshar D, Beglaibter N, Shikora S, Rosenthal RJ, Rubin M (2009) Gastric emptying is nor affected by sleeve gastrectomy–scintigraphic evaluation of gastric emptying after sleeve gastrectomy without removal of the gastric antrum. Obes Surg 19:293–298CrossRefPubMed
7.
go back to reference Melissas J, Daskalakis M, Koukouraki S, Askoxylakis I, Metaxari M, Dimitriadis E, Stathaki M, Papadakis JA (2008) Sleeve gastrectomy—a “food limiting” operation. Obes Surg 18:1251–1256CrossRefPubMed Melissas J, Daskalakis M, Koukouraki S, Askoxylakis I, Metaxari M, Dimitriadis E, Stathaki M, Papadakis JA (2008) Sleeve gastrectomy—a “food limiting” operation. Obes Surg 18:1251–1256CrossRefPubMed
8.
go back to reference Nakane Y, Michiura T, Inoue K, Sato M, Nakai K, Yamamichi K (2002) Length of the antral segment in pylorus-preserving gastrectomy. Br J Surg 89:220–224CrossRefPubMed Nakane Y, Michiura T, Inoue K, Sato M, Nakai K, Yamamichi K (2002) Length of the antral segment in pylorus-preserving gastrectomy. Br J Surg 89:220–224CrossRefPubMed
9.
go back to reference Ferrer-Márquez M, Belda-Lozano R, Ferrer-Ayza M (2012) Technical controversies in laparoscopic sleeve gastrectomy. Obes Surg 22:182–187CrossRefPubMed Ferrer-Márquez M, Belda-Lozano R, Ferrer-Ayza M (2012) Technical controversies in laparoscopic sleeve gastrectomy. Obes Surg 22:182–187CrossRefPubMed
10.
go back to reference Camilleri M, Malagelada JR, Brown ML, Becker G, Zinsmeister AR (1985) Relation between antral motility and gastric emptying of solids and liquids in humans. Am J Physiol 249:G580–G585PubMed Camilleri M, Malagelada JR, Brown ML, Becker G, Zinsmeister AR (1985) Relation between antral motility and gastric emptying of solids and liquids in humans. Am J Physiol 249:G580–G585PubMed
11.
go back to reference Siegel JA, Urbain JL, Adler LP, Charkes ND, Maurer AH, Krevsky B, Knight LC, Fisher RS, Malmud LS (1988) Biphasic nature of gastric emptying. Gut 29:85–89CrossRefPubMedPubMedCentral Siegel JA, Urbain JL, Adler LP, Charkes ND, Maurer AH, Krevsky B, Knight LC, Fisher RS, Malmud LS (1988) Biphasic nature of gastric emptying. Gut 29:85–89CrossRefPubMedPubMedCentral
12.
go back to reference Tougas G, Eaker EY, Abell TL, Abrahamsson H, Boivin M, Chen J, Hocking MP, Quigley EM, Koch KL, Tokayer AZ, Stanghellini V, Chen Y, Huizinga JD, Rydén J, Bourgeois I, McCallum RW (2000) Assessment of gastric emptying using a low fat meal: establishment of international control values. Am J Gastroenterol 95:1456–1462CrossRefPubMed Tougas G, Eaker EY, Abell TL, Abrahamsson H, Boivin M, Chen J, Hocking MP, Quigley EM, Koch KL, Tokayer AZ, Stanghellini V, Chen Y, Huizinga JD, Rydén J, Bourgeois I, McCallum RW (2000) Assessment of gastric emptying using a low fat meal: establishment of international control values. Am J Gastroenterol 95:1456–1462CrossRefPubMed
13.
go back to reference Baltasar A, Serra C, Pérez N, Bou R, Bengochea M, Ferri L (2005) Laparoscopic sleeve gastrectomy: a multi-purpose bariatric operation. Obes Surg 15:1124–1128CrossRefPubMed Baltasar A, Serra C, Pérez N, Bou R, Bengochea M, Ferri L (2005) Laparoscopic sleeve gastrectomy: a multi-purpose bariatric operation. Obes Surg 15:1124–1128CrossRefPubMed
14.
go back to reference Obeidat F, Shanti H, Mismar A, Albsoul N, Al-Qudah M (2005) The magnitude of antral resection in laparoscopic sleeve gastrectomy and its relationship to excess weight loss. Obes Surg 25:1928–1932CrossRef Obeidat F, Shanti H, Mismar A, Albsoul N, Al-Qudah M (2005) The magnitude of antral resection in laparoscopic sleeve gastrectomy and its relationship to excess weight loss. Obes Surg 25:1928–1932CrossRef
15.
go back to reference Baumann T, Kuesters S, Grueneberger J, Marjanovic G, Zimmermann L, Schaefer AO, Hopt UT, Langer M, Karcz WK (2011) Time-resolved MRI after ingestion of liquids reveals motility changes after laparoscopic sleeve gastrectomy—preliminary results. Obes Surg 21:95–101CrossRefPubMed Baumann T, Kuesters S, Grueneberger J, Marjanovic G, Zimmermann L, Schaefer AO, Hopt UT, Langer M, Karcz WK (2011) Time-resolved MRI after ingestion of liquids reveals motility changes after laparoscopic sleeve gastrectomy—preliminary results. Obes Surg 21:95–101CrossRefPubMed
16.
go back to reference Abdallah E, El Nakeeb A, Yousef T, Abdallah H, Abd Ellatif M, Lofty A, Youssef M, Elganash A, Moatamed A, Morshed M, Farid M (2014) Impact of extent of antral resection on surgical outcomes of sleeve gastrectomy for morbid obesity (a prospective randomized study). Obes Surg 24:1587–1594CrossRefPubMed Abdallah E, El Nakeeb A, Yousef T, Abdallah H, Abd Ellatif M, Lofty A, Youssef M, Elganash A, Moatamed A, Morshed M, Farid M (2014) Impact of extent of antral resection on surgical outcomes of sleeve gastrectomy for morbid obesity (a prospective randomized study). Obes Surg 24:1587–1594CrossRefPubMed
17.
go back to reference Michalsky D, Dvorak P, Belacek J, Kasalicky M (2013) Radical resection of the pyloric antrum and its effect on gastric emptying after sleeve gastrectomy. Obes Surg 23:567–573CrossRefPubMed Michalsky D, Dvorak P, Belacek J, Kasalicky M (2013) Radical resection of the pyloric antrum and its effect on gastric emptying after sleeve gastrectomy. Obes Surg 23:567–573CrossRefPubMed
Metadata
Title
Influence of antrum size on gastric emptying and weight-loss outcomes after laparoscopic sleeve gastrectomy (preliminary analysis of a randomized trial)
Authors
Meritxell Garay
Carmen Balagué
Carlos Rodríguez-Otero
Berta Gonzalo
Anna Domenech
Juan Carlos Pernas
Ignasi J. Gich
Inka Miñambres
Sonia Fernández-Ananín
Eduardo M. Targarona
Publication date
01-06-2018
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 6/2018
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-017-5972-4

Other articles of this Issue 6/2018

Surgical Endoscopy 6/2018 Go to the issue