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Published in: Surgical Endoscopy 6/2017

01-06-2017

Long-term outcome of peroral endoscopic myotomy for esophageal achalasia in patients with previous Heller myotomy

Authors: Helle Ø. Kristensen, Jakob Kirkegård, Daniel Willy Kjær, Frank Viborg Mortensen, Rastislav Kunda, Niels Christian Bjerregaard

Published in: Surgical Endoscopy | Issue 6/2017

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Abstract

Background

Peroral endoscopic myotomy (POEM) is an emerging procedure in the treatment of esophageal achalasia, a primary motility disorder. However, the long-term outcome of POEM in patients, who have previously undergone a Heller myotomy, is unknown.

Methods

Using a local database, we identified patients with esophageal achalasia, who underwent POEM. We compared patients with a previous Heller myotomy to those, who had received none or only non-surgical therapy prior to the POEM procedure. We conducted follow-up examinations at 3, 12, and 24 months following the procedure.

Results

We included 66 consecutive patients undergoing POEM for achalasia, of which 14 (21.2 %) had undergone a prior Heller myotomy. In both groups, the preoperative Eckardt score was 7. Postoperatively, the non-Heller group experienced a more pronounced symptom relief at both 3-, 12-, and 24-month follow-up compared with the Heller group, and there was a tendency for the effect of POEM to reduce over time. We suggest that there is a correlation between preoperative measurements of gastroesophageal sphincter pressures and the chance of a successful POEM.

Conclusions

POEM has a place in the treatment of esophageal achalasia in patients with a prior Heller myotomy and persistent symptoms as it is a safe procedure with acceptable long-term results.
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Metadata
Title
Long-term outcome of peroral endoscopic myotomy for esophageal achalasia in patients with previous Heller myotomy
Authors
Helle Ø. Kristensen
Jakob Kirkegård
Daniel Willy Kjær
Frank Viborg Mortensen
Rastislav Kunda
Niels Christian Bjerregaard
Publication date
01-06-2017
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 6/2017
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-016-5267-1

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