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Published in: Surgical Endoscopy 11/2016

01-11-2016

Outcomes associated with preoperative weight loss after laparoscopic Roux-en-Y gastric bypass

Authors: Camille Blackledge, Laura A. Graham, Allison A. Gullick, Joshua Richman, Richard Stahl, Jayleen Grams

Published in: Surgical Endoscopy | Issue 11/2016

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Abstract

Background

Laparoscopic Roux-en-Y gastric bypass (LRYGB) is an effective treatment for achieving and maintaining weight loss and for improving obesity-related comorbidities. As part of the approval process for bariatric surgery, many insurance companies require patients to have documented recent participation in a supervised weight loss program. The goal of this study was to evaluate the relationship of preoperative weight changes with outcomes following LRYGB.

Methods

A retrospective review was conducted of adult patients undergoing LRYGB between 2008 and 2012 at a single institution. Patients were stratified into quartiles based on % excess weight gain (0–4.99 % and ≥5 % EWG) and % excess weight loss (0–4.99 % and ≥5 % EWL). Generalized linear models were used to examine differences in postoperative weight outcomes at 6, 12, and 24 months. Covariates included in the final adjusted models were determined using backwards stepwise selection.

Results

Of the 300 patients included in the study, there were no significant demographic differences among the quartiles. However, there was an increased time to operation for patients who gained or lost ≥5 % excess body weight (p < 0.001). Although there was no statistical significance in postoperative complications, there was a higher rate of complications in patients with ≥5 % EWG compared to those with ≥5 % EWL (12.5 vs. 4.8 %, respectively; p = 0.29). Unadjusted and adjusted generalized linear models showed no statistically significant association between preoperative % excess weight change and weight loss outcomes at 24 months.

Conclusion

Patients with the greatest % preoperative excess weight change had the longest intervals from initial visit to operation. No significant differences were seen in perioperative and postoperative outcomes. This study suggests preoperative weight loss requirements may delay the time to operation without improving postoperative outcomes or weight loss.
Literature
1.
2.
3.
go back to reference Chang S, Stoll CRT, Song J, Varela E, Eagon CJ, Colditz GA (2014) The effectiveness and risks of bariatric surgery an updated systematic review and meta-analysis, 2003–2012. JAMA Surg 149:275–287CrossRefPubMedPubMedCentral Chang S, Stoll CRT, Song J, Varela E, Eagon CJ, Colditz GA (2014) The effectiveness and risks of bariatric surgery an updated systematic review and meta-analysis, 2003–2012. JAMA Surg 149:275–287CrossRefPubMedPubMedCentral
4.
go back to reference Buchwald H, Estok R, Fahrbach K, Banel D, Jensen MD, Pories WJ, Bantle JP, Sledge I (2009) Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 122:248–256CrossRefPubMed Buchwald H, Estok R, Fahrbach K, Banel D, Jensen MD, Pories WJ, Bantle JP, Sledge I (2009) Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 122:248–256CrossRefPubMed
5.
go back to reference Hinojosa MW, Varela JE, Smith BR, Che F, Nguyen NT (2009) Resolution of systemic hypertension after laparoscopic gastric bypass. J Gastrointest Surg 13:793–797CrossRefPubMed Hinojosa MW, Varela JE, Smith BR, Che F, Nguyen NT (2009) Resolution of systemic hypertension after laparoscopic gastric bypass. J Gastrointest Surg 13:793–797CrossRefPubMed
6.
go back to reference Crémieux P-Y, Ledoux S, Clerici C, Cremieux F, Buessing M (2010) The impact of bariatric surgery on comorbidities and medication use among obese patients. Obes Surg 20:861–870CrossRefPubMed Crémieux P-Y, Ledoux S, Clerici C, Cremieux F, Buessing M (2010) The impact of bariatric surgery on comorbidities and medication use among obese patients. Obes Surg 20:861–870CrossRefPubMed
7.
go back to reference Vest AR, Heneghan HM, Agarwal S, Schauer PR, Young JB (2012) Bariatric surgery and cardiovascular outcomes: a systematic review. Heart 98:1763–1777CrossRefPubMed Vest AR, Heneghan HM, Agarwal S, Schauer PR, Young JB (2012) Bariatric surgery and cardiovascular outcomes: a systematic review. Heart 98:1763–1777CrossRefPubMed
8.
go back to reference Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Brethauer SA, Naveneethan SD, Aminian A, Pothier CE, Kim ESH, Nissen SE, Kashyap SR, for the STAMPEDE Investigators (2014) Bariatric surgery versus intensive medical therapy for diabetes – 3-year outcomes. N Engl J Med 370:2002–2013CrossRefPubMed Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Brethauer SA, Naveneethan SD, Aminian A, Pothier CE, Kim ESH, Nissen SE, Kashyap SR, for the STAMPEDE Investigators (2014) Bariatric surgery versus intensive medical therapy for diabetes – 3-year outcomes. N Engl J Med 370:2002–2013CrossRefPubMed
9.
go back to reference Sjöström L, Peltonen M, Jacobson P, Ahlin S, Andersson-Assarsson J, Anveden Ǻ, Bouchard C, Carlsson B, Karason K, Lönroth H, Näslund I, Sjöström E, Taube M, Wedel H, Svensson P-A, Sjöholm K, Carlsson LMS (2014) Association of bariatric surgery with long-term remission of type 2 diabetes and with microvascular and macrovascular complications. JAMA 311:2297–2304CrossRefPubMed Sjöström L, Peltonen M, Jacobson P, Ahlin S, Andersson-Assarsson J, Anveden Ǻ, Bouchard C, Carlsson B, Karason K, Lönroth H, Näslund I, Sjöström E, Taube M, Wedel H, Svensson P-A, Sjöholm K, Carlsson LMS (2014) Association of bariatric surgery with long-term remission of type 2 diabetes and with microvascular and macrovascular complications. JAMA 311:2297–2304CrossRefPubMed
10.
go back to reference Courcoulas AP, Belle SH, Neiberg RH, Pierson SK, Eagleton JK, Kalarchian MA, DeLany JP, Lang W, Jakicic JM (2015) Three-year outcomes of bariatric surgery vs lifestyle intervention for type 2 diabetes mellitus treatment: a randomized clinical trial. JAMA Surg 150:931–940CrossRefPubMedPubMedCentral Courcoulas AP, Belle SH, Neiberg RH, Pierson SK, Eagleton JK, Kalarchian MA, DeLany JP, Lang W, Jakicic JM (2015) Three-year outcomes of bariatric surgery vs lifestyle intervention for type 2 diabetes mellitus treatment: a randomized clinical trial. JAMA Surg 150:931–940CrossRefPubMedPubMedCentral
11.
go back to reference Miras AD, Chuah LL, Khalil N, Nicotra A, Vusirikala A, Baqai N, Graham C, Ravindra S, Lascaratos G, Oliver N, le Roux CW (2015) Type 2 diabetes mellitus and microvascular complications 1 year after Roux-en-Y gastric bypass: a case-control study. Diabetologia 58:1443–1447CrossRefPubMedPubMedCentral Miras AD, Chuah LL, Khalil N, Nicotra A, Vusirikala A, Baqai N, Graham C, Ravindra S, Lascaratos G, Oliver N, le Roux CW (2015) Type 2 diabetes mellitus and microvascular complications 1 year after Roux-en-Y gastric bypass: a case-control study. Diabetologia 58:1443–1447CrossRefPubMedPubMedCentral
12.
go back to reference Brehauer S (2011) ASMBS position statement on preoperative supervised weight loss requirements. Surg Obes Relat Dis 7:257–260CrossRef Brehauer S (2011) ASMBS position statement on preoperative supervised weight loss requirements. Surg Obes Relat Dis 7:257–260CrossRef
13.
go back to reference Edholm D, Kullberg J, Haenni A, Karlsson FA, Ahlström A, Hedberg J, Ahlström H, Sundbom M (2011) Preoperative 4-week low-calorie diet reduces liver volume and intrahepatic fat, and facilitates laparoscopic gastric bypass in morbidly obese. Obes Surg 21:345–350CrossRefPubMed Edholm D, Kullberg J, Haenni A, Karlsson FA, Ahlström A, Hedberg J, Ahlström H, Sundbom M (2011) Preoperative 4-week low-calorie diet reduces liver volume and intrahepatic fat, and facilitates laparoscopic gastric bypass in morbidly obese. Obes Surg 21:345–350CrossRefPubMed
14.
go back to reference Livhits M, Mercado C, Yermilov I, Parikh JA, Dutson E, Mehran A, Ko CY, Gibbons MM (2009) Does weight loss immediately before bariatric surgery improve outcomes: a systematic review. Surg Obes Relat Dis 5:713–721CrossRefPubMed Livhits M, Mercado C, Yermilov I, Parikh JA, Dutson E, Mehran A, Ko CY, Gibbons MM (2009) Does weight loss immediately before bariatric surgery improve outcomes: a systematic review. Surg Obes Relat Dis 5:713–721CrossRefPubMed
15.
go back to reference Cassie S, Menezes C, Birch DW, Shi X, Karmali S (2011) Effect of preoperative weight loss in bariatric surgical patients: a systematic review. Surg Obes Relat Dis 7:760–768CrossRefPubMed Cassie S, Menezes C, Birch DW, Shi X, Karmali S (2011) Effect of preoperative weight loss in bariatric surgical patients: a systematic review. Surg Obes Relat Dis 7:760–768CrossRefPubMed
16.
go back to reference Ochner CN, Dambkowski CL, Yeomans BL, Teixeira J, Pi-Sunyer X (2012) Pre-bariatric surgery weight loss requirements and the effect of preoperative weight loss on postoperative outcome. Int J Obes 36:1380–1387CrossRef Ochner CN, Dambkowski CL, Yeomans BL, Teixeira J, Pi-Sunyer X (2012) Pre-bariatric surgery weight loss requirements and the effect of preoperative weight loss on postoperative outcome. Int J Obes 36:1380–1387CrossRef
17.
go back to reference Gerber P, Anderin C, Thorell A (2014) Weight loss prior to bariatric surgery: an updated review of the literature. Scan J Surg 104:33–39CrossRef Gerber P, Anderin C, Thorell A (2014) Weight loss prior to bariatric surgery: an updated review of the literature. Scan J Surg 104:33–39CrossRef
18.
go back to reference Dindo D, Demartines N, Clavien P (2004) Classification of surgical complications a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien P (2004) Classification of surgical complications a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral
19.
go back to reference Wickham H (2009) GGPLOT2: elegant graphics for data analysis. Springer, New YorkCrossRef Wickham H (2009) GGPLOT2: elegant graphics for data analysis. Springer, New YorkCrossRef
20.
go back to reference Wood SN (2006) Generalized additive models: an introduction with R, 1st edn. Chapman & Hall/CRC, New York Wood SN (2006) Generalized additive models: an introduction with R, 1st edn. Chapman & Hall/CRC, New York
21.
go back to reference Harrell FE Jr (2001) Regression modeling strategies with applications to linear models, logistic regression, and survival analysis. Springer, New York Harrell FE Jr (2001) Regression modeling strategies with applications to linear models, logistic regression, and survival analysis. Springer, New York
22.
go back to reference Jamal MK, DeMaria EJ, Johnson JM, Carmody BJ, Wolfe LG, Kellum JM, Meador JG (2006) Insurance-mandated preoperative dietary counseling does not improve outcome and increases dropout rates in patients considering gastric bypass surgery for morbid obesity. Surg Obes Relat Dis 2:122–127CrossRefPubMed Jamal MK, DeMaria EJ, Johnson JM, Carmody BJ, Wolfe LG, Kellum JM, Meador JG (2006) Insurance-mandated preoperative dietary counseling does not improve outcome and increases dropout rates in patients considering gastric bypass surgery for morbid obesity. Surg Obes Relat Dis 2:122–127CrossRefPubMed
23.
go back to reference Ochner CN, Puma LM, Raevuori A, Teixeira J, Geliebter A (2010) Effectiveness of a prebariatric surgery insurance-required weight loss regimen and relation to postsurgical weight loss. Obesity 18:287–292CrossRefPubMed Ochner CN, Puma LM, Raevuori A, Teixeira J, Geliebter A (2010) Effectiveness of a prebariatric surgery insurance-required weight loss regimen and relation to postsurgical weight loss. Obesity 18:287–292CrossRefPubMed
24.
go back to reference Kuwada TS, Richardson S, El Chaar M, Norton HJ, Cleek J, Tomcho J, Stefanidis D (2011) Insurance-mandated medical programs before bariatric surgery: do good things come to those who wait? Surg Obes Relat Dis 7:526–530CrossRefPubMed Kuwada TS, Richardson S, El Chaar M, Norton HJ, Cleek J, Tomcho J, Stefanidis D (2011) Insurance-mandated medical programs before bariatric surgery: do good things come to those who wait? Surg Obes Relat Dis 7:526–530CrossRefPubMed
25.
go back to reference Riess KP, Baker MT, Lambert PJ, Mathiason MA, Kothari SN (2008) Effect of preoperative weight loss on laparoscopic gastric bypass outcomes. Surg Obes Relat Dis 4:704–708CrossRefPubMed Riess KP, Baker MT, Lambert PJ, Mathiason MA, Kothari SN (2008) Effect of preoperative weight loss on laparoscopic gastric bypass outcomes. Surg Obes Relat Dis 4:704–708CrossRefPubMed
26.
go back to reference Benotti PN, Still CD, Wood GC, Akmal Y, King H, El Arousy H, Dancea H, Gerhard GS, Petrick A, Strodel W (2009) Preoperative weight loss before bariatric surgery. Arch Surg 144:1150–1155CrossRefPubMedPubMedCentral Benotti PN, Still CD, Wood GC, Akmal Y, King H, El Arousy H, Dancea H, Gerhard GS, Petrick A, Strodel W (2009) Preoperative weight loss before bariatric surgery. Arch Surg 144:1150–1155CrossRefPubMedPubMedCentral
27.
go back to reference Giordano S, Victorzon M (2013) The impact of preoperative weight loss before laparoscopic gastric bypass. Obes Surg 24:669–674CrossRef Giordano S, Victorzon M (2013) The impact of preoperative weight loss before laparoscopic gastric bypass. Obes Surg 24:669–674CrossRef
28.
go back to reference Anderin C, Gustafsson UO, Heijbel N, Thorell A (2015) Weight loss before bariatric surgery and postoperative complications: data from the Scandinavian Obesity Registry (SOReg). Ann Surg 261:909–913CrossRefPubMed Anderin C, Gustafsson UO, Heijbel N, Thorell A (2015) Weight loss before bariatric surgery and postoperative complications: data from the Scandinavian Obesity Registry (SOReg). Ann Surg 261:909–913CrossRefPubMed
Metadata
Title
Outcomes associated with preoperative weight loss after laparoscopic Roux-en-Y gastric bypass
Authors
Camille Blackledge
Laura A. Graham
Allison A. Gullick
Joshua Richman
Richard Stahl
Jayleen Grams
Publication date
01-11-2016
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 11/2016
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-016-4856-3

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