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Surgical Endoscopy
Published in: Surgical Endoscopy 5/2014

01-05-2014

Laparoscopic cytoreductive surgery and early postoperative intraperitoneal chemotherapy for patients with colorectal cancer peritoneal carcinomatosis: initial results from a single center

Authors: Soo Yeun Park, Gyu-Seog Choi, Jun Seok Park, Hye Jin Kim, Jong-Pil Ryuk, Sung-Hwan Yun, Jong Gwang Kim, Byung Woog Kang

Published in: Surgical Endoscopy | Issue 5/2014

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Abstract

Background

In recent decades, a combination of cytoreductive surgery and intraperitoneal chemotherapy has yielded improvements in the survival of patients with peritoneal carcinomatosis. Laparoscopic cytoreductive surgery and intraperitoneal chemotherapy comprise a challenging and rarely reported surgical procedure.

Methods

Between November 2004 and February 2010, 29 patients underwent cytoreductive surgery and early postoperative intraperitoneal chemotherapy for peritoneal carcinomatosis secondary to colorectal cancer. Of the 29 patients, 15 underwent laparoscopic surgery and 14 underwent open surgery.

Results

The patient characteristics did not differ significantly between the two groups. Synchronous peritoneal carcinomatosis with a primary tumor was more common in the laparoscopic group, and the Gilly stage of peritoneal carcinomatosis was found more frequently in the open group. Complication rate and hospital stay were less in the laparoscopic group. However, the outcomes for the patients undergoing the combined treatment were similar between the two groups with respect to completeness of cytoreduction, operation morbidity, and overall survival. The laparoscopic group had a cytoreduction completeness of 86.7 % and an operative morbidity of 13.3 %. Operative mortality occurred for one patient after open surgery.

Conclusions

Laparoscopic cytoreductive surgery and early postoperative intraperitoneal chemotherapy can be performed safely for selected patients with peritoneal carcinomatosis from colorectal cancer to a limited extent. Further studies with longer follow-up periods and larger numbers of patients are warranted to confirm the study findings.
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Metadata
Title
Laparoscopic cytoreductive surgery and early postoperative intraperitoneal chemotherapy for patients with colorectal cancer peritoneal carcinomatosis: initial results from a single center
Authors
Soo Yeun Park
Gyu-Seog Choi
Jun Seok Park
Hye Jin Kim
Jong-Pil Ryuk
Sung-Hwan Yun
Jong Gwang Kim
Byung Woog Kang
Publication date
01-05-2014
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 5/2014
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-013-3351-3

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