Skip to main content
Top
Published in: Surgical Endoscopy 12/2013

01-12-2013

Long-term outcome after laparoscopic fenestration of simple liver cysts

Authors: Francesco Ardito, Giuseppe Bianco, Maria Vellone, Gerardo Sarno, Giuseppina Ranucci, Ivo Giovannini, Felice Giuliante

Published in: Surgical Endoscopy | Issue 12/2013

Login to get access

Abstract

Background

Simple liver cysts (LCs) represent the most common benign liver disease, with a prevalence of 3–5 %. Laparoscopic fenestration is considered the best treatment for symptomatic LCs, but few studies have analyzed the rate or type of recurrence during a long-term follow-up period (>5 years).

Methods

Between January 2000 and December 2010, 47 patients underwent laparoscopic fenestration for simple LCs. The indications were symptoms for 42 patients and an uncertain diagnosis for five patients. The follow-up assessment consisted of regular patient evaluations, with results of laboratory data and liver ultrasound.

Results

Conversion to laparotomy was not necessary in any case. The postoperative mortality and morbidity rates were nil. The mean follow-up period was 67 months (range 12–142 months), and 26 patients (55.3 %) had a follow-up period longer than 5 years. During the follow-up period, 40 patients (85.1 %) did not present with any type of recurrence. The overall recurrence rate was 14.9 % (seven patients) based on five patients (10.6 %) with radiologic asymptomatic recurrences detected by ultrasound or computed tomography (CT) scan and two patients (4.3 %) with clinicoradiologic symptomatic recurrences. Both symptomatic recurrences involved LCs located in the right posterior segments.

Conclusions

Laparoscopic fenestration provided complete relief of symptoms for about 95 % of patients with simple LCs. Recurrence after surgery was experienced by 14.9 % of the patients, but only in 4.3 % (two patients) was this recurrence symptomatic requiring a second treatment. The site of recurrence was more frequently in the right posterior segments. Laparoscopic fenestration of symptomatic LCs can be considered a safe and effective procedure that can yield good long-term results.
Literature
1.
go back to reference Kamphues C, Rather M, Engel S, Schmidt SC, Neuhaus P, Seehofer D (2011) Laparoscopic fenestration of nonparasitic liver cysts and health-related quality-of-life assessment. Updates Surg 63:243–247PubMedCrossRef Kamphues C, Rather M, Engel S, Schmidt SC, Neuhaus P, Seehofer D (2011) Laparoscopic fenestration of nonparasitic liver cysts and health-related quality-of-life assessment. Updates Surg 63:243–247PubMedCrossRef
2.
go back to reference Caremani M, Vincenti A, Benci A, Sassoli S, Tacconi D (1993) Ecographic epidemiology of nonparasitic hepatic cyst. J Clin Ultrasound 21:115–118PubMedCrossRef Caremani M, Vincenti A, Benci A, Sassoli S, Tacconi D (1993) Ecographic epidemiology of nonparasitic hepatic cyst. J Clin Ultrasound 21:115–118PubMedCrossRef
4.
go back to reference Melnick PJ (1995) Polycystic liver. Arch Pathol 59:162 Melnick PJ (1995) Polycystic liver. Arch Pathol 59:162
5.
go back to reference Gigot JF, Hubert C, Banice R, Kendrick ML (2004) Laparoscopic management of benign liver diseases: where are we? HPB Oxford 6:197–212PubMedCrossRef Gigot JF, Hubert C, Banice R, Kendrick ML (2004) Laparoscopic management of benign liver diseases: where are we? HPB Oxford 6:197–212PubMedCrossRef
6.
go back to reference Giuliante F, D’Acapito F, Vellone M, Giovannini I, Nuzzo G (2003) Risk for laparoscopic fenestration of liver cysts. Surg Endosc 17:1735–1738PubMedCrossRef Giuliante F, D’Acapito F, Vellone M, Giovannini I, Nuzzo G (2003) Risk for laparoscopic fenestration of liver cysts. Surg Endosc 17:1735–1738PubMedCrossRef
7.
go back to reference Qiu JG, Wu H, Jiang H, Huang JW, Pankaj P, Xu YL, Wang JZ, Zeng Y (2011) Laparoscopic fenestration vs open fenestration in patients with congenital hepatic cysts: a meta-analysis. World J Gastroenterol 17:3359–3365PubMedCrossRef Qiu JG, Wu H, Jiang H, Huang JW, Pankaj P, Xu YL, Wang JZ, Zeng Y (2011) Laparoscopic fenestration vs open fenestration in patients with congenital hepatic cysts: a meta-analysis. World J Gastroenterol 17:3359–3365PubMedCrossRef
8.
go back to reference Klotz HP, Schlumpf R, Weder W, Largiadèr F (1993) Minimal invasive surgery for treatment of enlarged symptomatic liver cysts. Surg Laparosc Endosc 3:351–353PubMedCrossRef Klotz HP, Schlumpf R, Weder W, Largiadèr F (1993) Minimal invasive surgery for treatment of enlarged symptomatic liver cysts. Surg Laparosc Endosc 3:351–353PubMedCrossRef
9.
go back to reference Koperna T, Vogl S, Satzinger U, Schulz F (1997) Nonparasitic cysts of the liver: results and options of surgical treatment. World J Surg 21:850–854PubMedCrossRef Koperna T, Vogl S, Satzinger U, Schulz F (1997) Nonparasitic cysts of the liver: results and options of surgical treatment. World J Surg 21:850–854PubMedCrossRef
10.
go back to reference Everson GT, Taylor MR, Doctor RB (2004) Polycystic disease of the liver. Hepatology 40:774–782PubMed Everson GT, Taylor MR, Doctor RB (2004) Polycystic disease of the liver. Hepatology 40:774–782PubMed
11.
go back to reference Z’graggen K, Metzger A, Klaiber C (1991) Symptomatic simple cysts of the liver: treatment by laparoscopic surgery. Surg Endosc 5:224–225PubMedCrossRef Z’graggen K, Metzger A, Klaiber C (1991) Symptomatic simple cysts of the liver: treatment by laparoscopic surgery. Surg Endosc 5:224–225PubMedCrossRef
12.
go back to reference Fiamingo P, Tedeschi U, Veroux M, Cillo U, Brolese A, Da Rold A, Madia C, Zanus G, D’Amico DF (2003) Laparoscopic treatment of simple hepatic cysts and polycystic liver disease. Surg Endosc 17:623–626PubMedCrossRef Fiamingo P, Tedeschi U, Veroux M, Cillo U, Brolese A, Da Rold A, Madia C, Zanus G, D’Amico DF (2003) Laparoscopic treatment of simple hepatic cysts and polycystic liver disease. Surg Endosc 17:623–626PubMedCrossRef
13.
go back to reference Mazza OM, Fernandez DL, Pekolj J, Pfaffen G, Sanchez Clariá R, Molmenti EP, de Santibañes E (2009) Management of nonparasitic hepatic cysts. J Am Coll Surg 209:733–739PubMedCrossRef Mazza OM, Fernandez DL, Pekolj J, Pfaffen G, Sanchez Clariá R, Molmenti EP, de Santibañes E (2009) Management of nonparasitic hepatic cysts. J Am Coll Surg 209:733–739PubMedCrossRef
14.
go back to reference Loehe F, Globke B, Marnoto R, Bruns CJ, Graeb C, Winter H, Jauch KW, Angele MK (2010) Long-term results after surgical treatment of nonparasitic hepatic cysts. Am J Surg 200:23–31PubMedCrossRef Loehe F, Globke B, Marnoto R, Bruns CJ, Graeb C, Winter H, Jauch KW, Angele MK (2010) Long-term results after surgical treatment of nonparasitic hepatic cysts. Am J Surg 200:23–31PubMedCrossRef
15.
go back to reference Fabiani P, Iannelli A, Chevallier P, Benchimol D, Bourgeon A, Gugenheim J (2005) Long-term outcome after laparoscopic fenestration of symptomatic simple cysts of the liver. Br J Surg 92:596–597PubMedCrossRef Fabiani P, Iannelli A, Chevallier P, Benchimol D, Bourgeon A, Gugenheim J (2005) Long-term outcome after laparoscopic fenestration of symptomatic simple cysts of the liver. Br J Surg 92:596–597PubMedCrossRef
16.
go back to reference Litwin DE, Taylor BR, Langer B, Greig P (1987) Nonparasitic cysts of the liver: the case for conservative surgical management. Ann Surg 205:45–48PubMedCrossRef Litwin DE, Taylor BR, Langer B, Greig P (1987) Nonparasitic cysts of the liver: the case for conservative surgical management. Ann Surg 205:45–48PubMedCrossRef
17.
go back to reference Tocchi A, Mazzoni G, Costa G, Cassini D, Bettelli E, Agostini N, Miccini M (2002) Symptomatic nonparasitic hepatic cysts: options for and results of surgical management. Arch Surg 137:154–158PubMedCrossRef Tocchi A, Mazzoni G, Costa G, Cassini D, Bettelli E, Agostini N, Miccini M (2002) Symptomatic nonparasitic hepatic cysts: options for and results of surgical management. Arch Surg 137:154–158PubMedCrossRef
18.
go back to reference VanSonnenberg E, Wroblicka JT, D’Agostino HB, Mathieson JR, Casola G, O’Laoide R, Cooperberg PL (1994) Symptomatic hepatic cysts: percutaneous drainage and sclerosis. Radiology 190:387–392PubMed VanSonnenberg E, Wroblicka JT, D’Agostino HB, Mathieson JR, Casola G, O’Laoide R, Cooperberg PL (1994) Symptomatic hepatic cysts: percutaneous drainage and sclerosis. Radiology 190:387–392PubMed
19.
go back to reference Erdogan D, van Delden OM, Rauws EA, Busch OR, Lameris JS, Gouma DJ, van Gulik TM (2007) Results of percutaneous sclerotherapy and surgical treatment in patients with symptomatic simple liver cysts and polycystic liver disease. World J Gastroenterol 13:3095–3100PubMed Erdogan D, van Delden OM, Rauws EA, Busch OR, Lameris JS, Gouma DJ, van Gulik TM (2007) Results of percutaneous sclerotherapy and surgical treatment in patients with symptomatic simple liver cysts and polycystic liver disease. World J Gastroenterol 13:3095–3100PubMed
20.
go back to reference Yoshida H, Onda M, Tajiri T, Arima Y, Mamada Y, Taniai N, Akimaru K (2003) Long-term results of multiple minocycline hydrochloride injections for the treatment of symptomatic solitary hepatic cyst. J Gastroenterol Hepatol 18:595–598PubMedCrossRef Yoshida H, Onda M, Tajiri T, Arima Y, Mamada Y, Taniai N, Akimaru K (2003) Long-term results of multiple minocycline hydrochloride injections for the treatment of symptomatic solitary hepatic cyst. J Gastroenterol Hepatol 18:595–598PubMedCrossRef
21.
go back to reference Krâhenbühl L, Baer HU, Renzulli P, Z’graggen K, Frei E, Büchler MW (1996) Laparoscopic management of nonparasitic symptom-producing solitary hepatic cysts. J Am Coll Surg 183:493–498PubMed Krâhenbühl L, Baer HU, Renzulli P, Z’graggen K, Frei E, Büchler MW (1996) Laparoscopic management of nonparasitic symptom-producing solitary hepatic cysts. J Am Coll Surg 183:493–498PubMed
22.
go back to reference Konstadoulakis MM, Gomatos IP, Albanopoulos K, Alexakis N, Leandros E (2005) Laparoscopic fenestration for the treatment of patients with severe adult polycystic liver disease. Am J Surg 189:71–75PubMedCrossRef Konstadoulakis MM, Gomatos IP, Albanopoulos K, Alexakis N, Leandros E (2005) Laparoscopic fenestration for the treatment of patients with severe adult polycystic liver disease. Am J Surg 189:71–75PubMedCrossRef
23.
go back to reference Morino M, De Giuli M, Festa V, Garrone C (1994) Laparoscopic management of symptomatic nonparasitic cysts of the liver: indications and results. Ann Surg 219:157–164PubMedCrossRef Morino M, De Giuli M, Festa V, Garrone C (1994) Laparoscopic management of symptomatic nonparasitic cysts of the liver: indications and results. Ann Surg 219:157–164PubMedCrossRef
24.
go back to reference Bai XL, Liang TB, Yu J, Wang WL, Shen Y, Zhang M, Zheng SS (2007) Long-term results of laparoscopic fenestration for patients with congenital liver cysts. Hepatobiliary Pancreat Dis Int 6:600–603PubMed Bai XL, Liang TB, Yu J, Wang WL, Shen Y, Zhang M, Zheng SS (2007) Long-term results of laparoscopic fenestration for patients with congenital liver cysts. Hepatobiliary Pancreat Dis Int 6:600–603PubMed
25.
go back to reference Emmermann A, Zornig C, Lloyd DM, Peiper M, Bloechle C, Broelsch CE (1997) Laparoscopic treatment of nonparasitic cysts of the liver with omental transposition flap. Surg Endosc 11:734–736PubMedCrossRef Emmermann A, Zornig C, Lloyd DM, Peiper M, Bloechle C, Broelsch CE (1997) Laparoscopic treatment of nonparasitic cysts of the liver with omental transposition flap. Surg Endosc 11:734–736PubMedCrossRef
Metadata
Title
Long-term outcome after laparoscopic fenestration of simple liver cysts
Authors
Francesco Ardito
Giuseppe Bianco
Maria Vellone
Gerardo Sarno
Giuseppina Ranucci
Ivo Giovannini
Felice Giuliante
Publication date
01-12-2013
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 12/2013
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-013-3104-3

Other articles of this Issue 12/2013

Surgical Endoscopy 12/2013 Go to the issue