Top

Surgical Endoscopy

Published in:

01-10-2013

Effectiveness and safety of n-butyl-2-cyanoacrylate medical adhesive for noninvasive patch fixation in laparoscopic inguinal hernia repair

Authors: Ming-gang Wang, Mao-lin Tian, Xue-fei Zhao, Yu-sheng Nie, Jie Chen, Ying-mo Shen

Published in: Surgical Endoscopy | Issue 10/2013

Abstract

Background

Our purpose was to compare the recurrence rate and other clinical outcomes of laparoscopic (LS) transabdominal preperitoneal (TAPP) inguinal hernia repair using n-butyl-2-cyanoacrylate (NBCA) for mesh fixation with those of no mesh fixation and mesh fixation with titanium spiral tacks (ST).

Methods

The medical records of patients who received LS TAPP inguinal hernia repair between 2009 and 2012 at our institution were reviewed. Patients were included if the received LS TAPP with either no mesh fixation, mesh fixation with NBCA only, fixation with ST only, or fixation with NBCA + ST. Outcome measures were operation time, postoperative length of stay, visual analogue scale (VAS) pain score 24 h after surgery, postoperative complications, and hernia recurrence.

Results

A total of 1,027 TAPP cases were included. In 552 cases, meshes were fixed with NBCA only, in 89 cases only ST were used, in 47 cases ST and NBCA were used, and in 339 cases meshes were not fixed. The groups were comparable with respect to demographic and clinical characteristics. No surgical complications occurred in any group. VAS pain scores were significantly lower in the nonfixation and NBCA only groups (1.4 ± 0.6 and 1.3 ± 0.6, respectively) than in the ST and NBCA + ST groups (2.2 ± 0.9 and 2.2 ± 0.7, respectively; P = 0.001). The mean follow-up duration was ~19 months. At the final follow-up, no wound infections or hernia recurrences had occurred in any of the groups. No occurrence of chronic pain was noted in the nonfixation and NBCA only groups, whereas two cases (2.2%) were noted in the ST group and one case (2.1%) in the NBCA + ST group (P = 0.005).

Conclusions

The use of NBCA medical adhesive for noninvasive patch fixation in laparoscopic hernia repair (TAPP) is effective and safe.

Paajanen H (2002) Do absorbable mesh sutures cause less chronic pain than nonabsorbable sutures after Lichtenstein inguinal herniorrhaphy? Hernia 6(1):26–28PubMedCrossRef

Shen YM, Sun WB, Chen J, Liu SJ, Wang MG (2012) NBCA medical adhesive (n-butyl-2-cyanoacrylate) versus suture for patch fixation in Lichtenstein inguinal herniorrhaphy: a randomized controlled trial. Surgery 151(4):550–555PubMedCrossRef

Eldabe Mikhail A, Palomo Luquero A, Reoyo Pascual JF, Seco Gil JL (2012) Cir Esp 90(7):446–452PubMedCrossRef

Kaul A, Hutfless S, Le H, Hamed SA, Tymitz K, Nguyen H, Marohn MR (2012) Staple versus fibrin glue fixation in laparoscopic total extraperitoneal repair of inguinal hernia: a systematic review and meta-analysis. Surg Endosc 26(5):1269–1278PubMedCrossRef

Fortelny RH, Petter-Puchner AH, Glaser KS, Redl H (2012) Use of fibrin sealant (Tisseel/Tissucol) in hernia repair: a systematic review. Surg Endosc 26(7):1803–1812PubMedCrossRef

Kukleta JF, Freytag C, Weber M (2012) Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations. Hernia 16(2):153–162PubMedCrossRef

Jenkins ED, Melman L, Desai S, Brown SR, Frisella MM, Deeken CR, Matthews BD (2011) Evaluation of intraperitoneal placement of absorbable and nonabsorbable barrier coated mesh secured with fibrin sealant in a New Zealand white rabbit model. Surg Endosc 25(2):604–612PubMedCrossRef

Hong JJ, Cohn SM, Perez JM, Dolich MO, Brown M, McKenney MG (2002) Prospective study of the incidence and outcome of intra-abdominal hypertension and the abdominal compartment syndrome. Br J Surg 89(5):591–596PubMedCrossRef

Sugrue M, Bauman A, Jones F, Bishop G, Flabouris A, Parr M (2002) Clinical examination is an inaccurate predictor of intraabdominal pressure. World J Surg 26(12):1428–1431PubMedCrossRef

10.

An G, West MA (2008) Abdominal compartment syndrome: a concise clinical review. Crit Care Med 36(4):1304–1310PubMedCrossRef

11.

Cheatham ML, De Waele J, Kirkpatrick A, Sugrue M, Malbrain ML, Ivatury RR et al (2009) Criteria for a diagnosis of abdominal compartment syndrome. Can J Surg 52(4):315–316PubMed

12.

Jenkins ED, Melman L, Frisella MM, Deeken CR, Matthews BD (2010) Evaluation of acute fixation strength of absorbable and nonabsorbable barrier coated mesh secured with fibrin sealant. Hernia 14(5):505–509PubMedCrossRef

13.

Clarke T, Katkhouda N, Mason RJ, Cheng BC, Algra J, Olasky J et al (2011) Fibrin glue for intraperitoneal laparoscopic mesh fixation: a comparative study in a swine model. Surg Endosc 25(3):737–748PubMedCrossRef

14.

Eriksen JR, Bech JI, Linnemann D, Rosenberg J (2008) Laparoscopic intraperitoneal mesh fixation with fibrin sealant (Tisseel) versus. titanium tacks: a randomised controlled experimental study in pigs. Hernia 12(5):483–491PubMedCrossRef

15.

Dilege E, Deveci U, Erbil Y, Dinççağ A, Seven R, Ozarmagan S et al (2010) N-butyl cyanoacrylate versus conventional suturing for fixation of meshes in an incisional hernia model. J Invest Surg 23(5):262–266PubMedCrossRef

16.

Losi P, Burchielli S, Spiller D, Finotti V, Kull S, Briganti E et al (2010) Cyanoacrylate surgical glue as an alternative to suture threads for mesh fixation in hernia repair. J Surg Res 163(2):e53–e58PubMedCrossRef

17.

Fortelny RH, Petter-Puchner AH, May C, Jaksch W, Benesch T, Khakpour Z et al (2012) The impact of atraumatic fibrin sealant vs. staple mesh fixation in TAPP hernia repair on chronic pain and quality of life: results of a randomized controlled study. Surg Endosc 26(1):249–254PubMedCrossRef

18.

Bittner R, Gmähle E, Gmähle B, Schwarz J, Aasvang E, Kehlet H (2010) Lightweight mesh and noninvasive fixation: an effective concept for prevention of chronic pain with laparoscopic hernia repair (TAPP). Surg Endosc 24(12):2958–2964PubMedCrossRef

19.

Schäfer M, Vuilleumier H, Di Mare L, Demartines N (2010) Fibrin sealant for mesh fixation in endoscopic inguinal hernia repair: is there enough evidence for its routine use? Surg Laparosc Endosc Percutan Tech 20(4):205–212PubMedCrossRef

20.

Testini M, Lissidini G, Poli E, Gurrado A, Lardo D, Piccinni G (2010) A single-surgeon randomized trial comparing sutures, N-butyl-2-cyanoacrylate and human fibrin glue for mesh fixation during primary inguinal hernia repair. Can J Surg 53(3):155–160PubMed

21.

Fortelny RH, Glaser KS, Petter-Puchner AH (2007) Use of human fibrin glue (Tissucol) versus staples for mesh fixation in laparoscopic transabdominal preperitoneal hernioplasty. Ann Surg 246(5):903–904PubMedCrossRef

22.

Lepere M, Benchetrit S, Bertrand JC, Chalbet JY, Combier JP, Detruit B (2008) Laparoscopic resorbable mesh fixation. Assessment of an innovative disposable instrument delivering resorbable fixation devices: I-Clip(TM). Final results of a prospective multicentre clinical trial. Hernia 12(2):177–183PubMedCrossRef

23.

Cihan A, Ozdemir H, Uçan BH, Acun Z, Comert M, Tascilar O et al (2006) Fade or fate. Seroma in laparoscopic inguinal hernia repair. Surg Endosc 20(2):325–328PubMedCrossRef

24.

Beattie GC, Kumar S, Nixon SJ (2000) Laparoscopic total extraperitoneal hernia repair: mesh fixation is unnecessary. J Laparoendosc Adv Surg Tech A 10(2):71–73PubMedCrossRef

25.

Knook MTT, Weidema WF, Stassen LPS, van Steensel CJ (1999) Endoscopic total extraperitoneal repair of primary and recurrent inguinal hernias. Surg Endosc 13(5):507–511PubMedCrossRef

26.

Teng YJ, Pan SM, Liu YL, Yang KH, Zhang YC, Tian JH et al (2011) A meta-analysis of randomized controlled trials of fixation versus nonfixation of mesh in laparoscopic total extraperitoneal inguinal hernia repair. Surg Endosc 25:2849–2858PubMedCrossRef

27.

Sajid MS, Ladwa N, Kalra L, Hutson K, Sains P, Baig MK (2012) A meta-analysis examining the use of tacker fixation versus no-fixation of mesh in laparoscopic inguinal hernia repair. Int J Surg 10(5):224–231PubMedCrossRef

Title: Effectiveness and safety of n-butyl-2-cyanoacrylate medical adhesive for noninvasive patch fixation in laparoscopic inguinal hernia repair
Authors: Ming-gang Wang
Mao-lin Tian
Xue-fei Zhao
Yu-sheng Nie
Jie Chen
Ying-mo Shen
Publication date: 01-10-2013
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 10/2013
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-013-2970-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effectiveness and safety of n-butyl-2-cyanoacrylate medical adhesive for noninvasive patch fixation in laparoscopic inguinal hernia repair

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 10/2013

TransAnal Minimally Invasive Surgery (TAMIS) with SILS™ Port versus Transanal Endoscopic Microsurgery (TEM): a comparative experimental study

Needlescopic video-assisted wedge resection combined with the subcostal trans-diaphragmatic approach for undetermined peripheral pulmonary nodules

Real-time near-infrared fluorescent cholangiography could shorten operative time during robotic single-site cholecystectomy

Reply to: doi:10.1007/s00464-013-2958-8: Re: Prospective randomized clinical trial comparing laparoscopic cholecystectomy and hybrid natural orifice transluminal endoscopic surgery (NOTES) (NCT00835250)

Increase in gastroesophageal reflux disease symptoms and erosive esophagitis 1 year after laparoscopic sleeve gastrectomy among obese adults

The feasibility score for the Laparoscopic Appendicitis Score