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01-02-2013 | Letter to the Editor

Dynamic imaging in medicine and network biology

Author: Christof Hottenrott

Published in: Surgical Endoscopy | Issue 2/2013

Excerpt

Diagnostic accuracy concerning the depth of tumor invasion (T-stage) is crucial for therapeutic decision making and oncologic outcomes of patients with solid cancer. In gastric cancer treatment, decisions between endoscopic resection (T1m [mucosal] and selected T1sm [small submucosal good differentiated cancer]) and open or laparoscopic D2 gastrectomy (T1sm, T2, T3, selected T4) and between preoperative (neoadjuvant) and perioperative or postoperative adjuvant treatment strongly affect patients’ overall survival and quality-of-life [1‐3]. …

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Ziogas D, Roukos D (2008) Robotic surgery for rectal cancer: may it improve also survival? Surg Endosc 22:1405–1406PubMedCrossRef

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Roukos DH (2010) Complete genome sequencing and network modeling to overcome trastuzumab resistance. Pharmacogenomics 11(8):1039–1043PubMedCrossRef

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Roukos DH (2010) Next-generation, genome sequencing-based biomarkers: concerns and challenges for medical practice. Biomark Med 4(4):583–586PubMedCrossRef

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Roukos DH (2010) Next-generation sequencing and epigenome technologies: potential medical applications. Expert Rev Med Devices 7(6):723–726PubMedCrossRef

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Roukos DH (2011) Cancer genome explosion and systems biology: impact on surgical oncology? Ann Surg Oncol 18(1):12–15PubMedCrossRef

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26.

Roukos DH (2011) Translating epigenetics into an anticancer drug pipeline for solid tumors. Expert Rev Med Devices 8(4):409–413PubMedCrossRef

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Roukos DH (2012) Differential signalling transduction networks for clinical robustness. Expert Rev Proteomics 9(2):111–114PubMedCrossRef

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Title: Dynamic imaging in medicine and network biology
Author: Christof Hottenrott
Publication date: 01-02-2013
Publisher: Springer-Verlag
Published in: Surgical Endoscopy / Issue 2/2013
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-012-2467-1

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