Published in:
01-01-2011 | Breast Oncology
Cancer Genome Explosion and Systems Biology: Impact on Surgical Oncology?
Author:
Dimitrios H. Roukos, MD, PhD
Published in:
Annals of Surgical Oncology
|
Issue 1/2011
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Excerpt
Each human being and each cancer patient is unique. Based on this assessment provided by the current personal genomics revolution, the emerging conceptual design is great. By identifying the genetics, genomics, and epigenomics variants underlying cancer phenotype, we would move forward toward improving surgical oncology. A decade after the first draft of human full-genome sequence, what is the progress of “big” biology and science? How do these advances influence surgical oncology and what are the challenges to overcome in order to achieve a dramatic improvement in the personalized prevention and treatment of solid cancer? …