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Published in: Surgical Endoscopy 10/2012

01-10-2012 | Endoluminal Surgery

Cryorecanalization: keys to success

Authors: Aydın Yılmaz, Zafer Aktaş, İbrahim Onur Alici, Atalay Çağlar, Hilal Sazak, Fatma Ulus

Published in: Surgical Endoscopy | Issue 10/2012

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Abstract

Background

Symptomatic airway obstructions are common with endobronchial exophytic tumors and may result in lethal complications. Recently, a cryorecanalization procedure has emerged that plays a role in the immediate management of airway obstruction. This study was conducted to investigate the value of cryorecanalization for the immediate management of endobronchial obstructive pathology and to determine the factors that affect the success of the procedure.

Methods

We analyzed 40 patients with symptoms of airway obstruction who were admitted to our hospital from 2006 to 2010. Patients with exophytic stenosis due to primary bronchial or metastatic neoplasms who underwent cryorecanalization procedures were included. Patients were excluded if they had involvement of a major artery near the site of the intervention. The procedure was not performed on patients with coagulation abnormalities or thrombocyte count and aggregation problems. The data were collected retrospectively.

Results

Successful cryorecanalization was achieved in 72.5 % of patients. We found that the success rate was mainly related to the presence of the distal involvement and the older age of obstruction. Restenosis rate was 12.8 %. The mean survival time after the cryorecanalization procedure was 11 ± 12.7 months. No complications occurred in 14 patients. No severe bleeding was observed for any patients, and moderate hemorrhaging occurred in ten patients, which was stopped with an argon plasma coagulator. We experienced no intraoperative mortality.

Conclusions

Cryorecanalization is a successful and safe intervention for the immediate management of endobronchial stenosis. Appropriate patient selection and high success rates should be achieved after careful radiological assessments and with early management.
Literature
1.
go back to reference Cavaliere S, Venuta F, Foccoli P, Toninelli C, La Face B (1996) Endoscopic treatment of malignant airway obstructions in 2,008 patients. Chest 110:1536–1542PubMedCrossRef Cavaliere S, Venuta F, Foccoli P, Toninelli C, La Face B (1996) Endoscopic treatment of malignant airway obstructions in 2,008 patients. Chest 110:1536–1542PubMedCrossRef
2.
go back to reference Schumann C, Hetzel M, Babiak AJ, Hetzel J, Merk T, Wibmer T et al (2010) Endobronchial tumour debulking with a flexible cryoprobe for immediate treatment of malignant stenosis. J Thorac Cardiovasc Surg 139:997–1000PubMedCrossRef Schumann C, Hetzel M, Babiak AJ, Hetzel J, Merk T, Wibmer T et al (2010) Endobronchial tumour debulking with a flexible cryoprobe for immediate treatment of malignant stenosis. J Thorac Cardiovasc Surg 139:997–1000PubMedCrossRef
3.
go back to reference Bolliger CT, Sutedja TG, Strausz J, Freitag L (2006) Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents. Eur Respir J 27:1258–1271PubMedCrossRef Bolliger CT, Sutedja TG, Strausz J, Freitag L (2006) Therapeutic bronchoscopy with immediate effect: laser, electrocautery, argon plasma coagulation and stents. Eur Respir J 27:1258–1271PubMedCrossRef
4.
go back to reference Bolliger CT, Sutedja TG, Strausz J, Freitag L (2002) ERS/ATS statement on interventional pulmonology. Eur Respir J 19:356–373PubMedCrossRef Bolliger CT, Sutedja TG, Strausz J, Freitag L (2002) ERS/ATS statement on interventional pulmonology. Eur Respir J 19:356–373PubMedCrossRef
5.
go back to reference Vergnon JM, Huber RM, Moghissi K (2006) Place of cryotherapy, brachytherapy and photodynamic therapy in therapeutic bronchoscopy of lung cancers. Eur Respir J 28:200–218PubMedCrossRef Vergnon JM, Huber RM, Moghissi K (2006) Place of cryotherapy, brachytherapy and photodynamic therapy in therapeutic bronchoscopy of lung cancers. Eur Respir J 28:200–218PubMedCrossRef
6.
go back to reference Schumann C, Lepper PM, Barth TFE, Moller P, Kruger S (2009) Successful immediate cryorecanalization of a simultaneous high-grade tracheal and bronchial stenosis as rare manifestations of bronchial-associated lymphoid tissue lymphoma. J Thorac Cardiovasc Surg 137:e17–e19PubMedCrossRef Schumann C, Lepper PM, Barth TFE, Moller P, Kruger S (2009) Successful immediate cryorecanalization of a simultaneous high-grade tracheal and bronchial stenosis as rare manifestations of bronchial-associated lymphoid tissue lymphoma. J Thorac Cardiovasc Surg 137:e17–e19PubMedCrossRef
7.
go back to reference Hetzel M, Hetzel J, Schumann C, Marx N, Babiak A (2004) Cryorecanalization: a new approach for the immediate management of acute airway obstruction. J Thorac Cardiovasc Surg 127:1427–1431PubMedCrossRef Hetzel M, Hetzel J, Schumann C, Marx N, Babiak A (2004) Cryorecanalization: a new approach for the immediate management of acute airway obstruction. J Thorac Cardiovasc Surg 127:1427–1431PubMedCrossRef
8.
go back to reference Reichle G, Freitag L, Kullmann HJ, Prenzel R, Macha HN, Farin G (2000) Argon plasma coagulation in bronchology: a new method—alternative or complementary? Pneumologie 54:508–516PubMedCrossRef Reichle G, Freitag L, Kullmann HJ, Prenzel R, Macha HN, Farin G (2000) Argon plasma coagulation in bronchology: a new method—alternative or complementary? Pneumologie 54:508–516PubMedCrossRef
9.
go back to reference Deygas N, Froudarakis M, Ozenne G, Vergnon JM (2001) Cryotherapy in early superficial bronchogenic carcinoma. Chest 120:26–31PubMedCrossRef Deygas N, Froudarakis M, Ozenne G, Vergnon JM (2001) Cryotherapy in early superficial bronchogenic carcinoma. Chest 120:26–31PubMedCrossRef
10.
go back to reference Herth FJ, Eberhardt R, Becker HD, Ernst A (2005) Relief of malignant airway obstruction: a prospective and randomised comparison of five different endoscopic techniques. Chest 128(4):209S Herth FJ, Eberhardt R, Becker HD, Ernst A (2005) Relief of malignant airway obstruction: a prospective and randomised comparison of five different endoscopic techniques. Chest 128(4):209S
11.
go back to reference Mathur PN, Wolf KM, Busk MF, Briete WM, Datzman M (1996) Fiberoptic bronchoscopic cryotherapy in the management of tracheobronchial obstruction. Chest 110:718–723PubMedCrossRef Mathur PN, Wolf KM, Busk MF, Briete WM, Datzman M (1996) Fiberoptic bronchoscopic cryotherapy in the management of tracheobronchial obstruction. Chest 110:718–723PubMedCrossRef
12.
go back to reference Hetzel J, Hetzel M, Hasel C, Moeller P, Babiak A (2008) Old meets modern: the use of traditional cryoprobes in the age of molecular biology. Respiration 76:193–197PubMedCrossRef Hetzel J, Hetzel M, Hasel C, Moeller P, Babiak A (2008) Old meets modern: the use of traditional cryoprobes in the age of molecular biology. Respiration 76:193–197PubMedCrossRef
14.
go back to reference Babiak A, Hetzel J, Krishna G, Fritz P, Moeller P, Balli T, Hetzel M (2009) Transbronchial cryobiopsy: a new tool for lung biopsies. Respiration 78:203–208PubMedCrossRef Babiak A, Hetzel J, Krishna G, Fritz P, Moeller P, Balli T, Hetzel M (2009) Transbronchial cryobiopsy: a new tool for lung biopsies. Respiration 78:203–208PubMedCrossRef
15.
go back to reference Loo PS, Thomas SC, Nicolson MC, Fyfe MN, Kerr KM (2010) Subtyping of undifferentiated non-small cell carcinomas in bronchial biopsy specimens. J Thorac Oncol 5:442–447PubMedCrossRef Loo PS, Thomas SC, Nicolson MC, Fyfe MN, Kerr KM (2010) Subtyping of undifferentiated non-small cell carcinomas in bronchial biopsy specimens. J Thorac Oncol 5:442–447PubMedCrossRef
16.
go back to reference Du Rand IA, Barber PV, Goldring J et al (2011) British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults. Thorax 66:iii1–iii21PubMedCrossRef Du Rand IA, Barber PV, Goldring J et al (2011) British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults. Thorax 66:iii1–iii21PubMedCrossRef
Metadata
Title
Cryorecanalization: keys to success
Authors
Aydın Yılmaz
Zafer Aktaş
İbrahim Onur Alici
Atalay Çağlar
Hilal Sazak
Fatma Ulus
Publication date
01-10-2012
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 10/2012
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-012-2260-1

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