Skip to main content
Top
Published in: Surgical Endoscopy 4/2012

01-04-2012

The impact of body mass index on outcomes after laparoscopic cholecystectomy

Authors: Daniel T. Farkas, Dovid Moradi, David Moaddel, Kamal Nagpal, John Morgan Cosgrove

Published in: Surgical Endoscopy | Issue 4/2012

Login to get access

Abstract

Background

Laparoscopic cholecystectomy (LC) is the standard of care for gallstone disease. Some cases will be converted to open surgery and others will have complications, both leading to worse outcomes. The purpose of this study was to evaluate whether an increased body mass index (BMI) is associated with increased rates of conversion or complication.

Methods

A retrospective chart review of 1,027 patients who underwent an attempted LC between January 2006 and December 2009 was performed. Patients were divided into five groups depending on their BMI: 18.5–24.9, 25–29.9, 30–34.9, 35–39.9, and ≥40. The primary endpoints were conversion rates, complication rates, and postoperative length of stay (LOS). Multivariate logistic regression was used to identify independent risk factors for worse outcomes.

Results

There were 211 (20.5%), 325 (31.6%), 268 (26.1%), 135 (13.1%), and 88 (8.6%) patients in the groups with BMI values of 18.5–24.9, 25–29.9, 30–34.9, 35–39.9, and ≥40, respectively. Seventy-three patients (7.1%) required conversion to open surgery, and 64 patients (6.2%) developed complications. The rate of conversion was similar amongst all the BMI groups (P = 0.366), as was the rate of complication (P = 0.483). Mean (±SD) postoperative LOS was 1.74 ± 3.87 days, and there was no difference between the BMI groups (P = 0.596). Male gender and emergent cholecystectomy were independent predictors of increased conversions and complications. Diabetes was a risk factor for conversion, whereas age >65 years was a risk factor for complications.

Conclusions

Increased BMI was not associated with worse outcomes after LC. Compared with normal weight patients, obese and even morbidly obese patients have no increased risk of conversion to open surgery, nor is there an increased risk of perioperative complications. Obese and morbidly obese patients who require a cholecystectomy should be considered in the same category as normal weight patients, and LC should be the standard of care.
Literature
1.
go back to reference Trondsen E, Reiertsen O, Andersen OK, Kjaersgaard P (1993) Laparoscopic and open cholecystectomy. A prospective, randomized study. Eur J Surg 159:217–221PubMed Trondsen E, Reiertsen O, Andersen OK, Kjaersgaard P (1993) Laparoscopic and open cholecystectomy. A prospective, randomized study. Eur J Surg 159:217–221PubMed
2.
go back to reference Buanes T, Mjaland O (1996) Complications in laparoscopic and open cholecystectomy: a prospective comparative trial. Surg Laparosc Endosc 6:266–272PubMedCrossRef Buanes T, Mjaland O (1996) Complications in laparoscopic and open cholecystectomy: a prospective comparative trial. Surg Laparosc Endosc 6:266–272PubMedCrossRef
3.
go back to reference Cuschieri A, Dubois F, Mouiel J, Mouret P, Becker H, Buess G, Trede M, Troidl H (1991) The European experience with laparoscopic cholecystectomy. Am J Surg 161:385–387PubMedCrossRef Cuschieri A, Dubois F, Mouiel J, Mouret P, Becker H, Buess G, Trede M, Troidl H (1991) The European experience with laparoscopic cholecystectomy. Am J Surg 161:385–387PubMedCrossRef
4.
go back to reference Giger UF, Michel JM, Opitz I, Th Inderbitzin D, Kocher T, Krahenbuhl L (2006) Risk factors for perioperative complications in patients undergoing laparoscopic cholecystectomy: analysis of 22, 953 consecutive cases from the Swiss Association of Laparoscopic and Thoracoscopic Surgery database. J Am Coll Surg 203:723–728PubMedCrossRef Giger UF, Michel JM, Opitz I, Th Inderbitzin D, Kocher T, Krahenbuhl L (2006) Risk factors for perioperative complications in patients undergoing laparoscopic cholecystectomy: analysis of 22, 953 consecutive cases from the Swiss Association of Laparoscopic and Thoracoscopic Surgery database. J Am Coll Surg 203:723–728PubMedCrossRef
5.
go back to reference Simopoulos C, Botaitis S, Polychronidis A, Tripsianis G, Karayiannakis AJ (2005) Risk factors for conversion of laparoscopic cholecystectomy to open cholecystectomy. Surg Endosc 19:905–909PubMedCrossRef Simopoulos C, Botaitis S, Polychronidis A, Tripsianis G, Karayiannakis AJ (2005) Risk factors for conversion of laparoscopic cholecystectomy to open cholecystectomy. Surg Endosc 19:905–909PubMedCrossRef
6.
go back to reference Livingston EH, Rege RV (2004) A nationwide study of conversion from laparoscopic to open cholecystectomy. Am J Surg 188:205–211PubMedCrossRef Livingston EH, Rege RV (2004) A nationwide study of conversion from laparoscopic to open cholecystectomy. Am J Surg 188:205–211PubMedCrossRef
7.
go back to reference Chandio A, Timmons S, Majeed A, Twomey A, Aftab F (2009) Factors influencing the successful completion of laparoscopic cholecystectomy. JSLS 13:581–586PubMedCrossRef Chandio A, Timmons S, Majeed A, Twomey A, Aftab F (2009) Factors influencing the successful completion of laparoscopic cholecystectomy. JSLS 13:581–586PubMedCrossRef
8.
go back to reference Rosen M, Brody F, Ponsky J (2002) Predictive factors for conversion of laparoscopic cholecystectomy. Am J Surg 184:254–258PubMedCrossRef Rosen M, Brody F, Ponsky J (2002) Predictive factors for conversion of laparoscopic cholecystectomy. Am J Surg 184:254–258PubMedCrossRef
9.
go back to reference Murphy MM, Ng SC, Simons JP, Csikesz NG, Shah SA, Tseng JF (2010) Predictors of major complications after laparoscopic cholecystectomy: surgeon, hospital, or patient? J Am Coll Surg 211:73–80PubMedCrossRef Murphy MM, Ng SC, Simons JP, Csikesz NG, Shah SA, Tseng JF (2010) Predictors of major complications after laparoscopic cholecystectomy: surgeon, hospital, or patient? J Am Coll Surg 211:73–80PubMedCrossRef
10.
go back to reference Flegal KM, Carroll MD, Ogden CL, Curtin LR (2010) Prevalence and trends in obesity among U.S. adults, 1999–2008. JAMA 303:235–241PubMedCrossRef Flegal KM, Carroll MD, Ogden CL, Curtin LR (2010) Prevalence and trends in obesity among U.S. adults, 1999–2008. JAMA 303:235–241PubMedCrossRef
11.
go back to reference Simopoulos C, Polychronidis A, Botaitis S, Perente S, Pitiakoudis M (2005) Laparoscopic cholecystectomy in obese patients. Obes Surg 15:243–246PubMedCrossRef Simopoulos C, Polychronidis A, Botaitis S, Perente S, Pitiakoudis M (2005) Laparoscopic cholecystectomy in obese patients. Obes Surg 15:243–246PubMedCrossRef
12.
go back to reference Angrisani L, Lorenzo M, De Palma G, Sivero L, Catanzano C, Tesauro B, Persico G (1995) Laparoscopic cholecystectomy in obese patients compared with nonobese patients. Surg Laparosc Endosc 5:197–201PubMed Angrisani L, Lorenzo M, De Palma G, Sivero L, Catanzano C, Tesauro B, Persico G (1995) Laparoscopic cholecystectomy in obese patients compared with nonobese patients. Surg Laparosc Endosc 5:197–201PubMed
13.
go back to reference Tuveri M, Borsezio V, Calo PG, Medas F, Tuveri A, Nicolosi A (2009) Laparoscopic cholecystectomy in the obese: results with the traditional and fundus-first technique. J Laparoendosc Adv Surg Tech A 19:735–740PubMedCrossRef Tuveri M, Borsezio V, Calo PG, Medas F, Tuveri A, Nicolosi A (2009) Laparoscopic cholecystectomy in the obese: results with the traditional and fundus-first technique. J Laparoendosc Adv Surg Tech A 19:735–740PubMedCrossRef
14.
go back to reference World Health Organization (2000) Obesity: preventing and managing the global epidemic: report of a WHO consultation. World Health Organization, Geneva World Health Organization (2000) Obesity: preventing and managing the global epidemic: report of a WHO consultation. World Health Organization, Geneva
15.
go back to reference Tang B, Cuschieri A (2006) Conversions during laparoscopic cholecystectomy: risk factors and effects on patient outcome. J Gastrointest Surg 10:1081–1091PubMedCrossRef Tang B, Cuschieri A (2006) Conversions during laparoscopic cholecystectomy: risk factors and effects on patient outcome. J Gastrointest Surg 10:1081–1091PubMedCrossRef
16.
go back to reference Bingener-Casey J, Richards ML, Strodel WE, Schwesinger WH, Sirinek KR (2002) Reasons for conversion from laparoscopic to open cholecystectomy: a 10-year review. J Gastrointest Surg 6:800–805PubMedCrossRef Bingener-Casey J, Richards ML, Strodel WE, Schwesinger WH, Sirinek KR (2002) Reasons for conversion from laparoscopic to open cholecystectomy: a 10-year review. J Gastrointest Surg 6:800–805PubMedCrossRef
17.
go back to reference Wick EC, Hirose K, Shore AD, Clark JM, Gearhart SL, Efron J, Makary MA (2011) Surgical site infections and cost in obese patients undergoing colorectal surgery. Arch Surg 146:1068–1072PubMedCrossRef Wick EC, Hirose K, Shore AD, Clark JM, Gearhart SL, Efron J, Makary MA (2011) Surgical site infections and cost in obese patients undergoing colorectal surgery. Arch Surg 146:1068–1072PubMedCrossRef
18.
go back to reference Williams TK, Rosato EL, Kennedy EP, Chojnacki KA, Andrel J, Hyslop T, Doria C, Sauter PK, Bloom J, Yeo CJ, Berger AC (2009) Impact of obesity on perioperative morbidity and mortality after pancreaticoduodenectomy. J Am Coll Surg 208:210–217PubMedCrossRef Williams TK, Rosato EL, Kennedy EP, Chojnacki KA, Andrel J, Hyslop T, Doria C, Sauter PK, Bloom J, Yeo CJ, Berger AC (2009) Impact of obesity on perioperative morbidity and mortality after pancreaticoduodenectomy. J Am Coll Surg 208:210–217PubMedCrossRef
19.
go back to reference Hirose K, Shore AD, Wick EC, Weiner JP, Makary MA (2011) Pay for obesity? Pay-for-performance metrics neglect increased complication rates and cost for obese patients. J Gastrointest Surg 15:1128–1135PubMedCrossRef Hirose K, Shore AD, Wick EC, Weiner JP, Makary MA (2011) Pay for obesity? Pay-for-performance metrics neglect increased complication rates and cost for obese patients. J Gastrointest Surg 15:1128–1135PubMedCrossRef
20.
go back to reference Paajanen H, Suuronen S, Nordstrom P, Miettinen P, Niskanen L (2011) Laparoscopic versus open cholecystectomy in diabetic patients and postoperative outcome. Surg Endosc 25:764–770PubMedCrossRef Paajanen H, Suuronen S, Nordstrom P, Miettinen P, Niskanen L (2011) Laparoscopic versus open cholecystectomy in diabetic patients and postoperative outcome. Surg Endosc 25:764–770PubMedCrossRef
21.
go back to reference Chang WT, Lee KT, Huang MC, Chen JS, Chiang HC, Kuo KK, Chuang SC, Wang SR, Ker CG (2009) The impact of body mass index on laparoscopic cholecystectomy in Taiwan: an oriental experience. J Hepatobiliary Pancreat Surg 16:648–654PubMedCrossRef Chang WT, Lee KT, Huang MC, Chen JS, Chiang HC, Kuo KK, Chuang SC, Wang SR, Ker CG (2009) The impact of body mass index on laparoscopic cholecystectomy in Taiwan: an oriental experience. J Hepatobiliary Pancreat Surg 16:648–654PubMedCrossRef
22.
go back to reference Mullen JT, Davenport DL, Hutter MM, Hosokawa PW, Henderson WG, Khuri SF, Moorman DW (2008) Impact of body mass index on perioperative outcomes in patients undergoing major intra-abdominal cancer surgery. Ann Surg Oncol 15:2164–2172PubMedCrossRef Mullen JT, Davenport DL, Hutter MM, Hosokawa PW, Henderson WG, Khuri SF, Moorman DW (2008) Impact of body mass index on perioperative outcomes in patients undergoing major intra-abdominal cancer surgery. Ann Surg Oncol 15:2164–2172PubMedCrossRef
23.
go back to reference Dindo D, Muller MK, Weber M, Clavien PA (2003) Obesity in general elective surgery. Lancet 361:2032–2035PubMedCrossRef Dindo D, Muller MK, Weber M, Clavien PA (2003) Obesity in general elective surgery. Lancet 361:2032–2035PubMedCrossRef
24.
go back to reference Unger SW, Unger HM, Edelman DS, Scott JS, Rosenbaum G (1992) Obesity: an indication rather than contraindication to laparoscopic cholecystectomy. Obes Surg 2:29–31PubMedCrossRef Unger SW, Unger HM, Edelman DS, Scott JS, Rosenbaum G (1992) Obesity: an indication rather than contraindication to laparoscopic cholecystectomy. Obes Surg 2:29–31PubMedCrossRef
25.
go back to reference Liu B, Balkwill A, Spencer E, Beral V (2008) Relationship between body mass index and length of hospital stay for gallbladder disease. J Public Health (Oxf) 30:161–166CrossRef Liu B, Balkwill A, Spencer E, Beral V (2008) Relationship between body mass index and length of hospital stay for gallbladder disease. J Public Health (Oxf) 30:161–166CrossRef
26.
go back to reference Black JL, Macinko J (2010) The changing distribution and determinants of obesity in the neighborhoods of New York City, 2003–2007. Am J Epidemiol 171:765–775PubMedCrossRef Black JL, Macinko J (2010) The changing distribution and determinants of obesity in the neighborhoods of New York City, 2003–2007. Am J Epidemiol 171:765–775PubMedCrossRef
27.
go back to reference Sidhu RS, Raj PK, Treat RC, Scarcipino MA, Tarr SM (2007) Obesity as a factor in laparoscopic cholecystectomy. Surg Endosc 21:774–776PubMedCrossRef Sidhu RS, Raj PK, Treat RC, Scarcipino MA, Tarr SM (2007) Obesity as a factor in laparoscopic cholecystectomy. Surg Endosc 21:774–776PubMedCrossRef
28.
go back to reference Hawn MT, Bian J, Leeth RR, Ritchie G, Allen N, Bland KI, Vickers SM (2005) Impact of obesity on resource utilization for general surgical procedures. Ann Surg 241:821–826 discussion 826-828PubMedCrossRef Hawn MT, Bian J, Leeth RR, Ritchie G, Allen N, Bland KI, Vickers SM (2005) Impact of obesity on resource utilization for general surgical procedures. Ann Surg 241:821–826 discussion 826-828PubMedCrossRef
Metadata
Title
The impact of body mass index on outcomes after laparoscopic cholecystectomy
Authors
Daniel T. Farkas
Dovid Moradi
David Moaddel
Kamal Nagpal
John Morgan Cosgrove
Publication date
01-04-2012
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 4/2012
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-011-1978-5

Other articles of this Issue 4/2012

Surgical Endoscopy 4/2012 Go to the issue