Published in:
01-08-2011 | Letter
Challenges with identification of angiogenesis biomarkers in cancer
Authors:
Eugenia Halkia, Nikolaos Kalinoglou
Published in:
Surgical Endoscopy
|
Issue 8/2011
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Excerpt
Angiogenesis, the development of new blood vessels, plays an important role in cancer formation and metastasis. Therefore, antiangiogenic therapy for cancer treatment was developed and has become very popular in recent years. Inhibiting new tumor vessel formation and blood supply by agents can have therapeutic effects on cancer. This old concept recently has been translated into the development of targeted agents, such as bevacizumab (Avastin), that inhibit the vascular endothelial growth factor (VEGF) signaling pathway. …