Skip to main content
Top
Published in: Surgical Endoscopy 8/2011

01-08-2011

Application of fluorescent cholangiography to single-incision laparoscopic cholecystectomy

Authors: Takeaki Ishizawa, Junichi Kaneko, Yosuke Inoue, Nobuyuki Takemura, Yasuji Seyama, Taku Aoki, Yoshifumi Beck, Yasuhiko Sugawara, Kiyoshi Hasegawa, Nobuhiro Harada, Masayoshi Ijichi, Koji Kusaka, Masayuki Shibasaki, Yasutsugu Bandai, Norihiro Kokudo

Published in: Surgical Endoscopy | Issue 8/2011

Login to get access

Abstract

Background

Although the use of single-incision laparoscopic cholecystectomy (SILC) is spreading rapidly, this technique has disadvantages. It does not allow for sufficient surgical views to be obtained or for intraoperative radiographic cholangiography to be performed. Fluorescent cholangiography using a preoperative intravenous injection of indocyanine green (ICG) may be useful for identifying the biliary tract during both SILC and conventional laparoscopic cholecystectomy.

Methods

For seven patients undergoing SILC, 1 ml of ICG (2.5 mg) was administered by intravenous injection before the surgery. The prototype fluorescent imaging system consisted of a xenon light source and a 30° laparoscope (diameter, 10 mm) equipped with a charge-coupled device camera capable of filtering out light with wavelengths shorter than 810 nm. The laparoscope was introduced through an umbilical trocar. Fluorescent cholangiography then was performed by changing the color images to fluorescent images using a foot switch during dissection of the triangle of Calot.

Results

Fluorescent cholangiography identified the confluence between the cystic duct and the common hepatic duct in all seven patients before and throughout the dissection of the triangle of Calot. The interval from the injection of ICG to the first obtained fluorescent cholangiography before dissection of the triangle of Calot ranged from 35 to 75 min.

Conclusions

Fluorescent cholangiography enabled real-time identification of the extrahepatic bile ducts during SILC without necessitating catheterization of the bile duct. Such properties of fluorescent cholangiography are expected to be helpful for ensuring the safety of SILC and expanding the indications for the procedure.
Appendix
Available only for authorised users
Literature
1.
go back to reference Navarra G, Pozza E, Occhionorelli S, Carcoforo P, Donini I (1997) One-wound laparoscopic cholecystectomy. Br J Surg 84:695PubMedCrossRef Navarra G, Pozza E, Occhionorelli S, Carcoforo P, Donini I (1997) One-wound laparoscopic cholecystectomy. Br J Surg 84:695PubMedCrossRef
2.
go back to reference Curcillo PG II, Wu AS, Podolsky ER, Graybeal C, Katkhouda N, Saenz A, Dunham R, Fendley S, Neff M, Copper C, Bessler M, Gumbs AA, Norton M, Iannelli A, Mason R, Moazzez A, Cohen L, Mouhlas A, Poor A (2010) Single-port-access (SPA) cholecystectomy: a multi-institutional report of the first 297 cases. Surg Endosc 24:1854–1860PubMedCrossRef Curcillo PG II, Wu AS, Podolsky ER, Graybeal C, Katkhouda N, Saenz A, Dunham R, Fendley S, Neff M, Copper C, Bessler M, Gumbs AA, Norton M, Iannelli A, Mason R, Moazzez A, Cohen L, Mouhlas A, Poor A (2010) Single-port-access (SPA) cholecystectomy: a multi-institutional report of the first 297 cases. Surg Endosc 24:1854–1860PubMedCrossRef
3.
go back to reference Edwards C, Bradshaw A, Ahearne P, Dematos P, Humble T, Johnson R, Mauterer D, Soosaar P (2010) Single-incision laparoscopic cholecystectomy is feasible: initial experience with 80 cases. Surg Endosc 24:2241–2247PubMedCrossRef Edwards C, Bradshaw A, Ahearne P, Dematos P, Humble T, Johnson R, Mauterer D, Soosaar P (2010) Single-incision laparoscopic cholecystectomy is feasible: initial experience with 80 cases. Surg Endosc 24:2241–2247PubMedCrossRef
4.
go back to reference Palanivelu C, Rajan PS, Rangarajan M, Parthasarathi R, Senthilnathan P, Praveenraj P (2008) Transumbilical flexible endoscopic cholecystectomy in humans: first feasibility study using a hybrid technique. Endoscopy 40:428–431PubMedCrossRef Palanivelu C, Rajan PS, Rangarajan M, Parthasarathi R, Senthilnathan P, Praveenraj P (2008) Transumbilical flexible endoscopic cholecystectomy in humans: first feasibility study using a hybrid technique. Endoscopy 40:428–431PubMedCrossRef
5.
go back to reference Kuon Lee S, You YK, Park JH, Kim HJ, Lee KK, Kim DG (2009) Single-port transumbilical laparoscopic cholecystectomy: a preliminary study in 37 patients with gallbladder disease. J Laparoendosc Adv Surg Tech A 19:495–499PubMedCrossRef Kuon Lee S, You YK, Park JH, Kim HJ, Lee KK, Kim DG (2009) Single-port transumbilical laparoscopic cholecystectomy: a preliminary study in 37 patients with gallbladder disease. J Laparoendosc Adv Surg Tech A 19:495–499PubMedCrossRef
6.
go back to reference Rawlings A, Hodgett SE, Matthews BD, Strasberg SM, Quasebarth M, Brunt LM (2010) Single-incision laparoscopic cholecystectomy: initial experience with critical view of safety dissection and routine intraoperative cholangiography. J Am Coll Surg 211:1–7PubMedCrossRef Rawlings A, Hodgett SE, Matthews BD, Strasberg SM, Quasebarth M, Brunt LM (2010) Single-incision laparoscopic cholecystectomy: initial experience with critical view of safety dissection and routine intraoperative cholangiography. J Am Coll Surg 211:1–7PubMedCrossRef
7.
go back to reference Ishizawa T, Tamura S, Masuda K, Aoki T, Hasegawa K, Imamura H, Beck Y, Kokudo N (2008) Intraoperative fluorescent cholangiography using indocyanine green: a biliary road map for safe surgery. J Am Coll Surg 208:e1–e4PubMedCrossRef Ishizawa T, Tamura S, Masuda K, Aoki T, Hasegawa K, Imamura H, Beck Y, Kokudo N (2008) Intraoperative fluorescent cholangiography using indocyanine green: a biliary road map for safe surgery. J Am Coll Surg 208:e1–e4PubMedCrossRef
8.
go back to reference Ishizawa T, Bandai Y, Kokudo N (2009) Fluorescent cholangiography using indocyanine green for laparoscopic cholecystectomy: an initial experience. Arch Surg 144:381–382PubMedCrossRef Ishizawa T, Bandai Y, Kokudo N (2009) Fluorescent cholangiography using indocyanine green for laparoscopic cholecystectomy: an initial experience. Arch Surg 144:381–382PubMedCrossRef
9.
go back to reference Landsman ML, Kwant G, Mook GA, Zijlstra WG (1976) Light-absorbing properties, stability, and spectral stabilization of indocyanine green. J Appl Physiol 40:575–583PubMed Landsman ML, Kwant G, Mook GA, Zijlstra WG (1976) Light-absorbing properties, stability, and spectral stabilization of indocyanine green. J Appl Physiol 40:575–583PubMed
10.
go back to reference Mordon S, Devoisselle JM, Soulie-Begu S, Desmettre T (1998) Indocyanine green: physicochemical factors affecting its fluorescence in vivo. Microvasc Res 55:146–152PubMedCrossRef Mordon S, Devoisselle JM, Soulie-Begu S, Desmettre T (1998) Indocyanine green: physicochemical factors affecting its fluorescence in vivo. Microvasc Res 55:146–152PubMedCrossRef
11.
go back to reference Aoki T, Murakami M, Yasuda D, Shimizu Y, Kusano T, Matsuda K, Niiya T, Kato H, Murai N, Otsuka K, Kusano M, Kato T (2010) Intraoperative fluorescent imaging using indocyanine green for liver mapping and cholangiography. J Hepatobiliary Pancreat Sci 17:590–594PubMedCrossRef Aoki T, Murakami M, Yasuda D, Shimizu Y, Kusano T, Matsuda K, Niiya T, Kato H, Murai N, Otsuka K, Kusano M, Kato T (2010) Intraoperative fluorescent imaging using indocyanine green for liver mapping and cholangiography. J Hepatobiliary Pancreat Sci 17:590–594PubMedCrossRef
12.
go back to reference Ishizawa T, Bandai Y, Ijichi M, Kaneko J, Hasegawa K, Kokudo N (2010) Fluorescent cholangiography illuminating bile duct anatomy during laparoscopic cholecystectomy. Br J Surg 97:1369–1377PubMedCrossRef Ishizawa T, Bandai Y, Ijichi M, Kaneko J, Hasegawa K, Kokudo N (2010) Fluorescent cholangiography illuminating bile duct anatomy during laparoscopic cholecystectomy. Br J Surg 97:1369–1377PubMedCrossRef
13.
go back to reference Kusano M, Tajima Y, Yamazaki K, Kato M, Watanabe M, Miwa M (2008) Sentinel node mapping guided by indocyanine green fluorescence imaging: a new method for sentinel node navigation surgery in gastrointestinal cancer. Dig Surg 25:103–108PubMedCrossRef Kusano M, Tajima Y, Yamazaki K, Kato M, Watanabe M, Miwa M (2008) Sentinel node mapping guided by indocyanine green fluorescence imaging: a new method for sentinel node navigation surgery in gastrointestinal cancer. Dig Surg 25:103–108PubMedCrossRef
14.
go back to reference Harada K, Miwa M, Fukuyo T, Watanabe S, Enosawa S, Chiba T (2009) ICG fluorescence endoscope for visualization of the placental vascular network. Minim Invasive Ther Allied Technol 18:1–5PubMedCrossRef Harada K, Miwa M, Fukuyo T, Watanabe S, Enosawa S, Chiba T (2009) ICG fluorescence endoscope for visualization of the placental vascular network. Minim Invasive Ther Allied Technol 18:1–5PubMedCrossRef
15.
go back to reference Abe N, Takeuchi H, Ueki H, Yanagida O, Masaki T, Mori T, Sugiyama M, Atomi Y (2009) Single-port endoscopic cholecystectomy: a bridge between laparoscopic and translumenal endoscopic surgery. J Hepatobiliary Pancreat Surg 16:633–638PubMedCrossRef Abe N, Takeuchi H, Ueki H, Yanagida O, Masaki T, Mori T, Sugiyama M, Atomi Y (2009) Single-port endoscopic cholecystectomy: a bridge between laparoscopic and translumenal endoscopic surgery. J Hepatobiliary Pancreat Surg 16:633–638PubMedCrossRef
16.
17.
go back to reference Strasberg SM (2002) Avoidance of biliary injury during laparoscopic cholecystectomy. J Hepatobiliary Pancreat Surg 9:543–547PubMedCrossRef Strasberg SM (2002) Avoidance of biliary injury during laparoscopic cholecystectomy. J Hepatobiliary Pancreat Surg 9:543–547PubMedCrossRef
18.
go back to reference Speich R, Saesseli B, Hoffmann U, Neftel KA, Reichen J (1988) Anaphylactoid reactions after indocyanine-green administration. Ann Int Med 109:345–346PubMed Speich R, Saesseli B, Hoffmann U, Neftel KA, Reichen J (1988) Anaphylactoid reactions after indocyanine-green administration. Ann Int Med 109:345–346PubMed
19.
go back to reference Rodrigues EB, Meyer CH, Mennel S, Farah ME (2007) Mechanisms of intravitreal toxicity of indocyanine green dye: implications for chromovitrectomy. Retina 27:958–970PubMedCrossRef Rodrigues EB, Meyer CH, Mennel S, Farah ME (2007) Mechanisms of intravitreal toxicity of indocyanine green dye: implications for chromovitrectomy. Retina 27:958–970PubMedCrossRef
20.
go back to reference Marescaux J, Dallemagne B, Perretta S, Wattiez A, Mutter D, Coumaros D (2007) Surgery without scars: report of transluminal cholecystectomy in a human being. Arch Surg 142:823–827PubMedCrossRef Marescaux J, Dallemagne B, Perretta S, Wattiez A, Mutter D, Coumaros D (2007) Surgery without scars: report of transluminal cholecystectomy in a human being. Arch Surg 142:823–827PubMedCrossRef
Metadata
Title
Application of fluorescent cholangiography to single-incision laparoscopic cholecystectomy
Authors
Takeaki Ishizawa
Junichi Kaneko
Yosuke Inoue
Nobuyuki Takemura
Yasuji Seyama
Taku Aoki
Yoshifumi Beck
Yasuhiko Sugawara
Kiyoshi Hasegawa
Nobuhiro Harada
Masayoshi Ijichi
Koji Kusaka
Masayuki Shibasaki
Yasutsugu Bandai
Norihiro Kokudo
Publication date
01-08-2011
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 8/2011
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-011-1616-2

Other articles of this Issue 8/2011

Surgical Endoscopy 8/2011 Go to the issue