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Virchows Archiv
Published in: Virchows Archiv 2/2021

01-02-2021 | Brachytherapy | Original Article

ESGO/ESTRO/ESP Guidelines for the management of patients with endometrial carcinoma

Authors: Nicole Concin, Carien L. Creutzberg, Ignace Vergote, David Cibula, Mansoor Raza Mirza, Simone Marnitz, Jonathan A. Ledermann, Tjalling Bosse, Cyrus Chargari, Anna Fagotti, Christina Fotopoulou, Antonio González-Martín, Sigurd F. Lax, Domenica Lorusso, Christian Marth, Philippe Morice, Remi A. Nout, Dearbhaile E. O’Donnell, Denis Querleu, Maria Rosaria Raspollini, Jalid Sehouli, Alina E. Sturdza, Alexandra Taylor, Anneke M. Westermann, Pauline Wimberger, Nicoletta Colombo, François Planchamp, Xavier Matias-Guiu

Published in: Virchows Archiv | Issue 2/2021

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Abstract

A European consensus conference on endometrial carcinoma was held in 2014 to produce multidisciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial carcinoma published since 2014, the European Society of Gynaecological Oncology (ESGO), the European SocieTy for Radiotherapy & Oncology (ESTRO) and the European Society of Pathology (ESP) jointly decided to update these evidence-based guidelines and to cover new topics in order to improve the quality of care for women with endometrial carcinoma across Europe and worldwide. ESGO/ESTRO/ESP nominated an international multidisciplinary development group consisting of practicing clinicians and researchers who have demonstrated leadership and expertise in the care and research of endometrial carcinoma (27 experts across Europe). To ensure that the guidelines are evidence-based, the literature published since 2014, identified from a systematic search was reviewed and critically appraised. In the absence of any clear scientific evidence, judgment was based on the professional experience and consensus of the development group. The guidelines are thus based on the best available evidence and expert agreement. Prior to publication, the guidelines were reviewed by 191 independent international practitioners in cancer care delivery and patient representatives. The guidelines comprehensively cover endometrial carcinoma staging, definition of prognostic risk groups integrating molecular markers, pre- and intra-operative work-up, fertility preservation, management for early, advanced, metastatic, and recurrent disease and palliative treatment. Principles of radiotherapy and pathological evaluation are also defined.
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Metadata
Title
ESGO/ESTRO/ESP Guidelines for the management of patients with endometrial carcinoma
Authors
Nicole Concin
Carien L. Creutzberg
Ignace Vergote
David Cibula
Mansoor Raza Mirza
Simone Marnitz
Jonathan A. Ledermann
Tjalling Bosse
Cyrus Chargari
Anna Fagotti
Christina Fotopoulou
Antonio González-Martín
Sigurd F. Lax
Domenica Lorusso
Christian Marth
Philippe Morice
Remi A. Nout
Dearbhaile E. O’Donnell
Denis Querleu
Maria Rosaria Raspollini
Jalid Sehouli
Alina E. Sturdza
Alexandra Taylor
Anneke M. Westermann
Pauline Wimberger
Nicoletta Colombo
François Planchamp
Xavier Matias-Guiu
Publication date
01-02-2021
Publisher
Springer Berlin Heidelberg
Published in
Virchows Archiv / Issue 2/2021
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-020-03007-z

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