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Published in: Virchows Archiv 4/2019

01-04-2019 | Cancer Immunotherapy | Editorial

Cancer immunology, inflammation, and tolerance: an introduction

Authors: Stefan Dirnhofer, Alfred Zippelius

Published in: Virchows Archiv | Issue 4/2019

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Excerpt

In the last decade, groundbreaking achievements have been obtained in the field of oncology. These have been fueled by the strong belief that a better knowledge of genetic or molecular mechanisms sustaining cancer growth could be key for more efficacious treatments. The results of a number of clinical trials showed that only a minority of patients benefited from targeted therapies, thus underlying that something else was missing in the scenario composed by molecular signatures, trunk and branch mutations, and conventional histopathological features to expand clinical results to most patients. …
Metadata
Title
Cancer immunology, inflammation, and tolerance: an introduction
Authors
Stefan Dirnhofer
Alfred Zippelius
Publication date
01-04-2019
Publisher
Springer Berlin Heidelberg
Published in
Virchows Archiv / Issue 4/2019
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-019-02547-3

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