Skip to main content
Top
Published in: Langenbeck's Archives of Surgery 2/2022

Open Access 01-03-2022 | Pancreatoduodenostomy | State-of-the-Art Clinical Surgery

State-of-the-art surgery for pancreatic cancer

Published in: Langenbeck's Archives of Surgery | Issue 2/2022

Login to get access

Abstract

Background

The d evelopment of surgical techniques and specialization and specifically complication management in pancreatic surgery have improved surgical outcomes as well as oncological results in pancreatic surgery in recent decades. Historical morbidity and especially mortality rates of up to 80% have decreased to below 5% today. This review summarizes the current state of the art in pancreatic cancer surgery.

Methods

The present literature and clinical experience are summarized to give an overview of the present best practice in pancreatic surgery as one of the most advanced surgical disciplines today.

Results

Based on the available literature, three important aspects contribute to best patient care in pancreatic surgery, namely, surgical progress, interdisciplinary complication management, and multimodal oncological treatment in case of pancreatic cancer. In addition, minimally invasive and robotic procedures are currently fields of development and specific topics of research.

Conclusion

In experienced hands, pancreatic surgery—despite being one of the most challenging fields of surgery—is a safe domain today. The impact of multimodal, especially adjuvant, therapy for oncological indications is well established and evidence-based. New technologies are evolving and will be evaluated with high-evidence studies in the near future.
Literature
1.
go back to reference Crile G Jr (1970) The advantages of bypass operations over radical pancreatoduodenectomy in the treatment of pancreatic carcinoma. Surg Gynecol Obstet 130(6):1049–1053PubMed Crile G Jr (1970) The advantages of bypass operations over radical pancreatoduodenectomy in the treatment of pancreatic carcinoma. Surg Gynecol Obstet 130(6):1049–1053PubMed
2.
go back to reference Shapiro TM (1975) Adenocarcinoma of the pancreas: a statistical analysis of biliary bypass vs Whipple resection in good risk patients. Ann Surg 182(6):715–721PubMedPubMedCentralCrossRef Shapiro TM (1975) Adenocarcinoma of the pancreas: a statistical analysis of biliary bypass vs Whipple resection in good risk patients. Ann Surg 182(6):715–721PubMedPubMedCentralCrossRef
3.
go back to reference Michelassi F, Erroi F, Dawson PJ, Pietrabissa A, Noda S, Handcock M et al (1989) Experience with 647 consecutive tumors of the duodenum, ampulla, head of the pancreas, and distal common bile duct. Ann Surg 210(4):544–556PubMedPubMedCentralCrossRef Michelassi F, Erroi F, Dawson PJ, Pietrabissa A, Noda S, Handcock M et al (1989) Experience with 647 consecutive tumors of the duodenum, ampulla, head of the pancreas, and distal common bile duct. Ann Surg 210(4):544–556PubMedPubMedCentralCrossRef
4.
go back to reference Nakase A, Matsumoto Y, Uchida K, Honjo I (1977) Surgical treatment of cancer of the pancreas and the periampullary region: cumulative results in 57 institutions in Japan. Ann Surg 185(1):52–57PubMedPubMedCentralCrossRef Nakase A, Matsumoto Y, Uchida K, Honjo I (1977) Surgical treatment of cancer of the pancreas and the periampullary region: cumulative results in 57 institutions in Japan. Ann Surg 185(1):52–57PubMedPubMedCentralCrossRef
5.
go back to reference Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA et al (1997) Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 226(3):248–257PubMedPubMedCentralCrossRef Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA et al (1997) Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 226(3):248–257PubMedPubMedCentralCrossRef
6.
go back to reference Trede M, Schwall G, Saeger HD (1990) Survival after pancreatoduodenectomy. 118 consecutive resections without an operative mortality. Ann Surg 211(4):447–58PubMedPubMedCentralCrossRef Trede M, Schwall G, Saeger HD (1990) Survival after pancreatoduodenectomy. 118 consecutive resections without an operative mortality. Ann Surg 211(4):447–58PubMedPubMedCentralCrossRef
7.
go back to reference Sohn TA, Yeo CJ, Cameron JL, Geschwind JF, Mitchell SE, Venbrux AC, Lillemoe KD (2003) Pancreaticoduodenectomy: role of interventional radiologists in managing patients and complications. J Gastrointest Surg 7(2):209–219PubMedCrossRef Sohn TA, Yeo CJ, Cameron JL, Geschwind JF, Mitchell SE, Venbrux AC, Lillemoe KD (2003) Pancreaticoduodenectomy: role of interventional radiologists in managing patients and complications. J Gastrointest Surg 7(2):209–219PubMedCrossRef
9.
go back to reference Conroy T, Hammel P, Hebbar M, Ben Abdelghani M, Wei AC, Raoul JL, Choné L, Francois E, Artru P, Biagi JJ, Lecomte T, Assenat E, Faroux R, Ychou M, Volet J, Sauvanet A, Breysacher G, Di Fiore F, Cripps C, Kavan P, Texereau P, Bouhier-Leporrier K, Khemissa-Akouz F, Legoux JL, Juzyna B, Gourgou S, O’Callaghan CJ, Jouffroy-Zeller C, Rat P, Malka D, Castan F, Bachet JB, Canadian Cancer Trials Group and the Unicancer-GI–PRODIGE Group (2018) FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer. N Engl J Med. 379(25):2395–2406PubMedCrossRef Conroy T, Hammel P, Hebbar M, Ben Abdelghani M, Wei AC, Raoul JL, Choné L, Francois E, Artru P, Biagi JJ, Lecomte T, Assenat E, Faroux R, Ychou M, Volet J, Sauvanet A, Breysacher G, Di Fiore F, Cripps C, Kavan P, Texereau P, Bouhier-Leporrier K, Khemissa-Akouz F, Legoux JL, Juzyna B, Gourgou S, O’Callaghan CJ, Jouffroy-Zeller C, Rat P, Malka D, Castan F, Bachet JB, Canadian Cancer Trials Group and the Unicancer-GI–PRODIGE Group (2018) FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer. N Engl J Med. 379(25):2395–2406PubMedCrossRef
11.
go back to reference Zureikat AH, Beane JD, Zenati MS, Al Abbas AI, Boone BA, Moser AJ, Bartlett DL, Hogg ME, Zeh HJ 3rd (2021) 500 Minimally invasive robotic pancreatoduodenectomies: one decade of optimizing performance. Ann Surg 273(5):966–972PubMedCrossRef Zureikat AH, Beane JD, Zenati MS, Al Abbas AI, Boone BA, Moser AJ, Bartlett DL, Hogg ME, Zeh HJ 3rd (2021) 500 Minimally invasive robotic pancreatoduodenectomies: one decade of optimizing performance. Ann Surg 273(5):966–972PubMedCrossRef
12.
go back to reference Neoptolemos JP, Palmer DH, Ghaneh P, Psarelli EE, Valle JW, Halloran CM et al (2017) Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. Lancet (London, England) 389(10073):1011–1024CrossRef Neoptolemos JP, Palmer DH, Ghaneh P, Psarelli EE, Valle JW, Halloran CM et al (2017) Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. Lancet (London, England) 389(10073):1011–1024CrossRef
13.
go back to reference Versteijne E, Suker M, Groothuis K, Akkermans-Vogelaar JM, Besselink MG, Bonsing BA et al (2020) Preoperative chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: results of the Dutch randomized phase III PREOPANC trial. J Clin Oncol 38:1763–1773PubMedPubMedCentralCrossRef Versteijne E, Suker M, Groothuis K, Akkermans-Vogelaar JM, Besselink MG, Bonsing BA et al (2020) Preoperative chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: results of the Dutch randomized phase III PREOPANC trial. J Clin Oncol 38:1763–1773PubMedPubMedCentralCrossRef
14.
go back to reference Ghaneh P, Palmer DH, Cicconi S, Halloran C, Psarelli EE, Rawcliffe CL, Sripadam R, Mukherjee S, Wadsley J, Al-Mukhtar A, Jiao LR, Wasan HS, Carter R, Graham JS, Ammad F, Evans J, Tjaden C, Hackert T, Buchler MW, Neoptolemos JP, European Study Group for Pancreatic Cancer (ESPAC) (2020) ESPAC-5F: Four-arm, prospective, multicenter, international randomized phase II trial of immediate surgery compared with neoadjuvant gemcitabine plus capecitabine (GEMCAP) or FOLFIRINOX or chemoradiotherapy (CRT) in patients with borderline resectable pancreatic cancer. Journal of Clinical Oncology 38(15_suppl):4505–4505CrossRef Ghaneh P, Palmer DH, Cicconi S, Halloran C, Psarelli EE, Rawcliffe CL, Sripadam R, Mukherjee S, Wadsley J, Al-Mukhtar A, Jiao LR, Wasan HS, Carter R, Graham JS, Ammad F, Evans J, Tjaden C, Hackert T, Buchler MW, Neoptolemos JP, European Study Group for Pancreatic Cancer (ESPAC) (2020) ESPAC-5F: Four-arm, prospective, multicenter, international randomized phase II trial of immediate surgery compared with neoadjuvant gemcitabine plus capecitabine (GEMCAP) or FOLFIRINOX or chemoradiotherapy (CRT) in patients with borderline resectable pancreatic cancer. Journal of Clinical Oncology 38(15_suppl):4505–4505CrossRef
15.
go back to reference Katz MHG, Shi Q, Meyers JP, Herman JM, Choung M, Wolpin BM, Ahmad S, de Wilton Marsh R, Schwartz LH, Behr S, Frankel WL, Collisson EA, Leenstra JL, Williams TM, Vaccaro GM, Venook AP, Meyerhardt JA, O’Reilly EM (2021) Alliance A021501: Preoperative mFOLFIRINOX or mFOLFIRINOX plus hypofractionated radiation therapy (RT) for borderline resectable (BR) adenocarcinoma of the pancreas. J Clin Oncol 39(3_suppl):377–377CrossRef Katz MHG, Shi Q, Meyers JP, Herman JM, Choung M, Wolpin BM, Ahmad S, de Wilton Marsh R, Schwartz LH, Behr S, Frankel WL, Collisson EA, Leenstra JL, Williams TM, Vaccaro GM, Venook AP, Meyerhardt JA, O’Reilly EM (2021) Alliance A021501: Preoperative mFOLFIRINOX or mFOLFIRINOX plus hypofractionated radiation therapy (RT) for borderline resectable (BR) adenocarcinoma of the pancreas. J Clin Oncol 39(3_suppl):377–377CrossRef
16.
go back to reference Hackert T, Sachsenmaier M, Hinz U, Schneider L, Michalski CW, Springfeld C, Strobel O, Jäger D, Ulrich A, Büchler MW (2016) Locally advanced pancreatic cancer: neoadjuvant therapy with Folfirinox results in resectability in 60% of the patients. Ann Surg 264(3):457–463PubMedCrossRef Hackert T, Sachsenmaier M, Hinz U, Schneider L, Michalski CW, Springfeld C, Strobel O, Jäger D, Ulrich A, Büchler MW (2016) Locally advanced pancreatic cancer: neoadjuvant therapy with Folfirinox results in resectability in 60% of the patients. Ann Surg 264(3):457–463PubMedCrossRef
17.
go back to reference Isaji S, Mizuno S, Windsor JA, Bassi C, Fernández-Del Castillo C, Hackert T et al (2018) International consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017. Pancreatology 18:2–11PubMedCrossRef Isaji S, Mizuno S, Windsor JA, Bassi C, Fernández-Del Castillo C, Hackert T et al (2018) International consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017. Pancreatology 18:2–11PubMedCrossRef
18.
go back to reference Oba A, Del Chiaro M, Satoi S, Kim SW, Takahashi H, Yu J, Hioki M, Tanaka M, Kato Y, Ariake K, Wu YHA, Yosuke I, Takahashi Y, Hackert T, Wolfgang CL, Besselink MG, Schulick RD, Nagakawa Y, Isaji S, Tsuchida A, Endo I (2021) New criteria of resectability for pancreatic cancer: a position paper by the Japanese Society of Hepato-Biliary-Pancreatic Surgery (JSHBPS). JSHBPS Oba A, Del Chiaro M, Satoi S, Kim SW, Takahashi H, Yu J, Hioki M, Tanaka M, Kato Y, Ariake K, Wu YHA, Yosuke I, Takahashi Y, Hackert T, Wolfgang CL, Besselink MG, Schulick RD, Nagakawa Y, Isaji S, Tsuchida A, Endo I (2021) New criteria of resectability for pancreatic cancer: a position paper by the Japanese Society of Hepato-Biliary-Pancreatic Surgery (JSHBPS). JSHBPS
20.
go back to reference Traverso LW, Longmire WP Jr (1978) Preservation of the pylorus in pancreaticoduodenectomy. Surg Gynecol Obstet 146(6):959–962PubMed Traverso LW, Longmire WP Jr (1978) Preservation of the pylorus in pancreaticoduodenectomy. Surg Gynecol Obstet 146(6):959–962PubMed
21.
go back to reference Klaiber U, Probst P, Strobel O, Michalski CW, Dörr-Harim C, Diener MK, Büchler MW, Hackert T (2018) Meta-analysis of delayed gastric emptying after pylorus-preserving versus pylorus-resecting pancreatoduodenectomy. Br J Surg 105(4):339–349PubMedCrossRef Klaiber U, Probst P, Strobel O, Michalski CW, Dörr-Harim C, Diener MK, Büchler MW, Hackert T (2018) Meta-analysis of delayed gastric emptying after pylorus-preserving versus pylorus-resecting pancreatoduodenectomy. Br J Surg 105(4):339–349PubMedCrossRef
22.
go back to reference Eshuis WJ, van Eijck CH, Gerhards MF, Coene PP, de Hingh IH, Karsten TM, Bonsing BA, Gerritsen JJ, Bosscha K, Spillenaar Bilgen EJ, Haverkamp JA, Busch OR, van Gulik TM, Reitsma JB, Gouma DJ (2014) Antecolic versus retrocolic route of the gastroenteric anastomosis after pancreatoduodenectomy: a randomized controlled trial. Ann Surg 259(1):45–51PubMedCrossRef Eshuis WJ, van Eijck CH, Gerhards MF, Coene PP, de Hingh IH, Karsten TM, Bonsing BA, Gerritsen JJ, Bosscha K, Spillenaar Bilgen EJ, Haverkamp JA, Busch OR, van Gulik TM, Reitsma JB, Gouma DJ (2014) Antecolic versus retrocolic route of the gastroenteric anastomosis after pancreatoduodenectomy: a randomized controlled trial. Ann Surg 259(1):45–51PubMedCrossRef
23.
go back to reference Sanjay P, Takaori K, Govil S, Shrikhande SV, Windsor JA (2012) “Artery-first” approaches to pancreatoduodenectomy. Br J Surg 99(8):1027–1035PubMedCrossRef Sanjay P, Takaori K, Govil S, Shrikhande SV, Windsor JA (2012) “Artery-first” approaches to pancreatoduodenectomy. Br J Surg 99(8):1027–1035PubMedCrossRef
24.
go back to reference Ironside N, Barreto SG, Loveday B, Shrikhande SV, Windsor JA, Pandanaboyana S (2018) Meta-analysis of an artery-first approach versus standard pancreatoduodenectomy on perioperative outcomes and survival. Br J Surg 105(6):628–636PubMedCrossRef Ironside N, Barreto SG, Loveday B, Shrikhande SV, Windsor JA, Pandanaboyana S (2018) Meta-analysis of an artery-first approach versus standard pancreatoduodenectomy on perioperative outcomes and survival. Br J Surg 105(6):628–636PubMedCrossRef
25.
go back to reference Sabater L, Cugat E, Serrablo A, Suarez-Artacho G, Diez-Valladares L, Santoyo-Santoyo J, Martín-Pérez E, Ausania F, Lopez-Ben S, Jover-Navalon JM, Garcés-Albir M, Garcia-Domingo MI, Serradilla M, Pérez-Aguirre E, Sánchez-Pérez B, Di Martino M, Senra-Del-Rio P, Falgueras-Verdaguer L, Carabias A, Gómez-Mateo MC, Ferrandez A, Dorcaratto D, Muñoz-Forner E, Fondevila C, Padillo J (2019) Does the artery-first approach improve the rate of R0 resection in pancreatoduodenectomy?: A multicenter, randomized, controlled trial. Ann Surg 270(5):738–746PubMedCrossRef Sabater L, Cugat E, Serrablo A, Suarez-Artacho G, Diez-Valladares L, Santoyo-Santoyo J, Martín-Pérez E, Ausania F, Lopez-Ben S, Jover-Navalon JM, Garcés-Albir M, Garcia-Domingo MI, Serradilla M, Pérez-Aguirre E, Sánchez-Pérez B, Di Martino M, Senra-Del-Rio P, Falgueras-Verdaguer L, Carabias A, Gómez-Mateo MC, Ferrandez A, Dorcaratto D, Muñoz-Forner E, Fondevila C, Padillo J (2019) Does the artery-first approach improve the rate of R0 resection in pancreatoduodenectomy?: A multicenter, randomized, controlled trial. Ann Surg 270(5):738–746PubMedCrossRef
26.
go back to reference Hackert T, Werner J, Weitz J, Schmidt J, Büchler MW (2010) Uncinate process first—a novel approach for pancreatic head resection. Langenbecks Arch Surg 395:1161–1164PubMedCrossRef Hackert T, Werner J, Weitz J, Schmidt J, Büchler MW (2010) Uncinate process first—a novel approach for pancreatic head resection. Langenbecks Arch Surg 395:1161–1164PubMedCrossRef
27.
go back to reference Pędziwiatr M, Pisarska M, Małczak P, Major P, Wierdak M, Radkowiak D, Kulawik J, Dembiński M, Budzyński A (2017) Laparoscopic uncinate process first pancreatoduodenectomy-feasibility study of a modified “artery first” approach to pancreatic head cancer. Langenbecks Arch Surg 402(6):917–923PubMedPubMedCentralCrossRef Pędziwiatr M, Pisarska M, Małczak P, Major P, Wierdak M, Radkowiak D, Kulawik J, Dembiński M, Budzyński A (2017) Laparoscopic uncinate process first pancreatoduodenectomy-feasibility study of a modified “artery first” approach to pancreatic head cancer. Langenbecks Arch Surg 402(6):917–923PubMedPubMedCentralCrossRef
28.
go back to reference Chen XM, Sun DL, Zhang Y (2018) Laparoscopic versus open pancreaticoduodenectomy combined with uncinated process approach: a comparative study evaluating perioperative outcomes (Retrospective cohort study). Int J Surg 51:170–173PubMedCrossRef Chen XM, Sun DL, Zhang Y (2018) Laparoscopic versus open pancreaticoduodenectomy combined with uncinated process approach: a comparative study evaluating perioperative outcomes (Retrospective cohort study). Int J Surg 51:170–173PubMedCrossRef
29.
go back to reference Hackert T, Strobel O, Michalski CW, Mihaljevic AL, Mehrabi A, Müller-Stich B et al (2017) The TRIANGLE operation – radical surgery after neoadjuvant treatment for advanced pancreatic cancer: a single arm observational study. HPB 19:1001–1007PubMedCrossRef Hackert T, Strobel O, Michalski CW, Mihaljevic AL, Mehrabi A, Müller-Stich B et al (2017) The TRIANGLE operation – radical surgery after neoadjuvant treatment for advanced pancreatic cancer: a single arm observational study. HPB 19:1001–1007PubMedCrossRef
30.
go back to reference Rosso E, Zimmitto G, Ianelli A, Garatti M (2020) The “TRIANGLE Operation” by laparoscopy: radical pancreaticoduodenectomy with major vascular resection for borderline resectable pancreatic head cancer. Ann Surg Oncol. 27(5):1613–1614PubMedCrossRef Rosso E, Zimmitto G, Ianelli A, Garatti M (2020) The “TRIANGLE Operation” by laparoscopy: radical pancreaticoduodenectomy with major vascular resection for borderline resectable pancreatic head cancer. Ann Surg Oncol. 27(5):1613–1614PubMedCrossRef
31.
go back to reference Klotz R, Hackert T, Heger P, Probst P, Hinz U, Loos M, Berchtold C, Mehrabi A, Schneider M, Müller-Stich BP, Strobel O, Diener MK, Mihaljevic AL, Büchler MW (2021) The TRIANGLE operation for pancreatic head and body cancers: early postoperative outcomes. HPB (Oxford) S1365–182X(21)00614–6 Klotz R, Hackert T, Heger P, Probst P, Hinz U, Loos M, Berchtold C, Mehrabi A, Schneider M, Müller-Stich BP, Strobel O, Diener MK, Mihaljevic AL, Büchler MW (2021) The TRIANGLE operation for pancreatic head and body cancers: early postoperative outcomes. HPB (Oxford) S1365–182X(21)00614–6
32.
go back to reference Diener MK, Mihaljevic AL, Strobel O, Loos M, Schmidt T, Schneider M, Berchtold C, Mehrabi A, Müller-Stich BP, Jiang K, Neoptolemos JP, Hackert T, Miao Y, Büchler MW (2020) Periarterial divestment in pancreatic cancer surgery. Surgery S0039–6060(20)30597–3 Diener MK, Mihaljevic AL, Strobel O, Loos M, Schmidt T, Schneider M, Berchtold C, Mehrabi A, Müller-Stich BP, Jiang K, Neoptolemos JP, Hackert T, Miao Y, Büchler MW (2020) Periarterial divestment in pancreatic cancer surgery. Surgery S0039–6060(20)30597–3
33.
go back to reference Strasberg SM, Drebin JA, Linehan D (2003) Radical antegrade modular pancreatosplenectomy. Surgery 133(5):521–527PubMedCrossRef Strasberg SM, Drebin JA, Linehan D (2003) Radical antegrade modular pancreatosplenectomy. Surgery 133(5):521–527PubMedCrossRef
34.
go back to reference Appleby LH (1953) The coeliac axis in the expansion of the operation for gastric carcinoma. Cancer 6:704–707PubMedCrossRef Appleby LH (1953) The coeliac axis in the expansion of the operation for gastric carcinoma. Cancer 6:704–707PubMedCrossRef
35.
go back to reference Klompmaker S, de Roii T, Korteweg JJ, van Dieren S, van Lienden KP, van Gulik TM, Busch OR, Besselink MG (2016) Systematic review of outcomes after distal pancreatectomy with coeliac axis resection for locally advanced pancreatic cancer. Br J Surg 103:941–949PubMedCrossRef Klompmaker S, de Roii T, Korteweg JJ, van Dieren S, van Lienden KP, van Gulik TM, Busch OR, Besselink MG (2016) Systematic review of outcomes after distal pancreatectomy with coeliac axis resection for locally advanced pancreatic cancer. Br J Surg 103:941–949PubMedCrossRef
36.
go back to reference Ueda A, Sakai N, Yoshitomi H, Furukawa K, Takayashiki T, Kuboki S, Takano S, Suzuki D, Kagawa S, Mishima T, Nakadai E, Miyazaki M, Ohtsuka M (2019) Is hepatic artery coil embolization useful in distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic cancer? World J Surg Oncol 17(1):124PubMedPubMedCentralCrossRef Ueda A, Sakai N, Yoshitomi H, Furukawa K, Takayashiki T, Kuboki S, Takano S, Suzuki D, Kagawa S, Mishima T, Nakadai E, Miyazaki M, Ohtsuka M (2019) Is hepatic artery coil embolization useful in distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic cancer? World J Surg Oncol 17(1):124PubMedPubMedCentralCrossRef
37.
go back to reference Moore GE, Sako Y, Thomas LB (1951) Radical pancreatoduodenectomy with resection and reanastomosis of the superior mesenteric vein. Surgery 30:550–553PubMed Moore GE, Sako Y, Thomas LB (1951) Radical pancreatoduodenectomy with resection and reanastomosis of the superior mesenteric vein. Surgery 30:550–553PubMed
38.
go back to reference Fortner JG (1973) Regional resection of cancer of the pancreas: a new surgical approach. Surgery 73:307–320PubMed Fortner JG (1973) Regional resection of cancer of the pancreas: a new surgical approach. Surgery 73:307–320PubMed
39.
go back to reference Bockhorn M, Uzunoglu FG, Adham M, Imrie C, Milicevic M, Sandberg AA, Asbun HJ, Bassi C, Büchler M, Charnley RM, Conlon K, Cruz LF, Dervenis C, Fingerhutt A, Friess H, Gouma DJ, Hartwig W, Lillemoe KD, Montorsi M, Neoptolemos JP, Shrikhande SV, Takaori K, Traverso W, Vashist YK, Vollmer C, Yeo CJ, Izbicki JR, International Study Group of Pancreatic Surgery (2014) Borderline resectable pancreatic cancer: a consensus statement by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 155(6):977–88PubMedCrossRef Bockhorn M, Uzunoglu FG, Adham M, Imrie C, Milicevic M, Sandberg AA, Asbun HJ, Bassi C, Büchler M, Charnley RM, Conlon K, Cruz LF, Dervenis C, Fingerhutt A, Friess H, Gouma DJ, Hartwig W, Lillemoe KD, Montorsi M, Neoptolemos JP, Shrikhande SV, Takaori K, Traverso W, Vashist YK, Vollmer C, Yeo CJ, Izbicki JR, International Study Group of Pancreatic Surgery (2014) Borderline resectable pancreatic cancer: a consensus statement by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 155(6):977–88PubMedCrossRef
40.
go back to reference Fancellu A, Petrucciani N, Porcu A, Deiana G, Sanna V, Ninniri C, Perra T, Celoria V, Nigri G (2020) The impact on survival and morbidity of portal-mesenteric resection during pancreaticoduodenectomy for pancreatic head adenocarcinoma: a systematic review and meta-analysis of comparative studies. Cancers (Basel) 12(7):1976CrossRef Fancellu A, Petrucciani N, Porcu A, Deiana G, Sanna V, Ninniri C, Perra T, Celoria V, Nigri G (2020) The impact on survival and morbidity of portal-mesenteric resection during pancreaticoduodenectomy for pancreatic head adenocarcinoma: a systematic review and meta-analysis of comparative studies. Cancers (Basel) 12(7):1976CrossRef
41.
go back to reference Belfiori G, Fiorentini G, Tamburrino D, Partelli S, Pagnanelli M, Gasparini G, Castoldi R, Balzano G, Rubini C, Zamboni G, Crippa S, Falconi M (2021) Vascular resection during pancreatectomy for pancreatic head cancer: a technical issue or a prognostic sign? Surgery 169(2):403–410PubMedCrossRef Belfiori G, Fiorentini G, Tamburrino D, Partelli S, Pagnanelli M, Gasparini G, Castoldi R, Balzano G, Rubini C, Zamboni G, Crippa S, Falconi M (2021) Vascular resection during pancreatectomy for pancreatic head cancer: a technical issue or a prognostic sign? Surgery 169(2):403–410PubMedCrossRef
42.
go back to reference Murakami Y, Satoi S, Motoi F, Sho M, Kawai M, Matsumoto I, Honda G, Multicentre Study Group of Pancreatobiliary Surgery (MSG-PBS) (2015) Portal or superior mesenteric vein resection in pancreatoduodenectomy for pancreatic head carcinoma. Br J Surg. 102(7):837–46PubMedCrossRef Murakami Y, Satoi S, Motoi F, Sho M, Kawai M, Matsumoto I, Honda G, Multicentre Study Group of Pancreatobiliary Surgery (MSG-PBS) (2015) Portal or superior mesenteric vein resection in pancreatoduodenectomy for pancreatic head carcinoma. Br J Surg. 102(7):837–46PubMedCrossRef
43.
go back to reference Mollberg N, Rahbari NN, Koch M, Hartwig W, Hoeger Y, Büchler MW, Weitz J (2011) Arterial resection during pancreatectomy for pancreatic cancer: a systematic review and meta-analysis. Ann Surg 254(6):882–893PubMedCrossRef Mollberg N, Rahbari NN, Koch M, Hartwig W, Hoeger Y, Büchler MW, Weitz J (2011) Arterial resection during pancreatectomy for pancreatic cancer: a systematic review and meta-analysis. Ann Surg 254(6):882–893PubMedCrossRef
44.
go back to reference Loos M, Kester T, Klaiber U, Mihaljevic AL, Mehrabi A, Müller-Stich BM, Diener MK, Schneider MA, Berchtold C, Hinz U, Feisst M, Strobel O, Hackert T, Büchler MW (2020) Arterial resection in pancreatic cancer surgery: effective after a learning curve. Ann Surg. https://doi.org/10.1097/SLA.0000000000004054 Loos M, Kester T, Klaiber U, Mihaljevic AL, Mehrabi A, Müller-Stich BM, Diener MK, Schneider MA, Berchtold C, Hinz U, Feisst M, Strobel O, Hackert T, Büchler MW (2020) Arterial resection in pancreatic cancer surgery: effective after a learning curve. Ann Surg. https://​doi.​org/​10.​1097/​SLA.​0000000000004054​
45.
go back to reference Tee MC, Krajewski AC, Groeschl RT, Farnell MB, Nagorney DM, Kendrick ML, Cleary SP, Smoot RL, Croome KP, Truty MJ (2018) Indications and perioperative outcomes for pancreatectomy with arterial resection. J Am Coll Surg 227(2):255–269PubMedCrossRef Tee MC, Krajewski AC, Groeschl RT, Farnell MB, Nagorney DM, Kendrick ML, Cleary SP, Smoot RL, Croome KP, Truty MJ (2018) Indications and perioperative outcomes for pancreatectomy with arterial resection. J Am Coll Surg 227(2):255–269PubMedCrossRef
46.
go back to reference Del Chiaro M, Rangelova E, Halimi A, Ateeb Z, Scandavini C, Valente R, Segersvärd R, Arnelo U, Verbeke CS (2019) Pancreatectomy with arterial resection is superior to palliation in patients with borderline resectable or locally advanced pancreatic cancer. HPB (Oxford) 21(2):219–225CrossRef Del Chiaro M, Rangelova E, Halimi A, Ateeb Z, Scandavini C, Valente R, Segersvärd R, Arnelo U, Verbeke CS (2019) Pancreatectomy with arterial resection is superior to palliation in patients with borderline resectable or locally advanced pancreatic cancer. HPB (Oxford) 21(2):219–225CrossRef
47.
go back to reference van Hilst J, de Rooij T, Bosscha K, Brinkman DJ, van Dieren S, Dijkgraaf MG, Gerhards MF, de Hingh IH, Karsten TM, Lips DJ, Luyer MD, Busch OR, Festen S, Besselink MG, Dutch Pancreatic Cancer Group (2019) Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled phase 2/3 trial. Lancet. Gastroenterol Hepatol. 4(3):199–207PubMedCrossRef van Hilst J, de Rooij T, Bosscha K, Brinkman DJ, van Dieren S, Dijkgraaf MG, Gerhards MF, de Hingh IH, Karsten TM, Lips DJ, Luyer MD, Busch OR, Festen S, Besselink MG, Dutch Pancreatic Cancer Group (2019) Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled phase 2/3 trial. Lancet. Gastroenterol Hepatol. 4(3):199–207PubMedCrossRef
48.
go back to reference Nickel F, Haney CM, Kowalewski KF, Probst P, Limen EF, Kalkum E, Diener MK, Strobel O, Müller-Stich BP, Hackert T (2020) Laparoscopic versus open pancreaticoduodenectomy: a systematic review and meta-analysis of randomized controlled trials. Ann Surg 271(1):54–66PubMedCrossRef Nickel F, Haney CM, Kowalewski KF, Probst P, Limen EF, Kalkum E, Diener MK, Strobel O, Müller-Stich BP, Hackert T (2020) Laparoscopic versus open pancreaticoduodenectomy: a systematic review and meta-analysis of randomized controlled trials. Ann Surg 271(1):54–66PubMedCrossRef
49.
go back to reference Wang M, Li D, Chen R, Huang X, Li J, Liu Y, Liu J, Cheng W, Chen X, Zhao W, Li J, Tan Z, Huang H, Li D, Zhu F, Qin T, Ma J, Yu G, Zhou B, Zheng S, Tang Y, Han W, Meng L, Ke J, Feng F, Chen B, Yin X, Chen W, Ma H, Xu J, Liu Y, Lin R, Dong Y, Yu Y, Liu J, Zhang H, Qin R, Minimally invasive treatment group in the pancreatic disease branch of China’s international exchange and promotion association for medicine and healthcare (MITG-P-CPAM) (2021) Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours: a multicentre, open-label, randomised controlled trial. Lancet Gastroenterol Hepatol. 6(6):438–447PubMedCrossRef Wang M, Li D, Chen R, Huang X, Li J, Liu Y, Liu J, Cheng W, Chen X, Zhao W, Li J, Tan Z, Huang H, Li D, Zhu F, Qin T, Ma J, Yu G, Zhou B, Zheng S, Tang Y, Han W, Meng L, Ke J, Feng F, Chen B, Yin X, Chen W, Ma H, Xu J, Liu Y, Lin R, Dong Y, Yu Y, Liu J, Zhang H, Qin R, Minimally invasive treatment group in the pancreatic disease branch of China’s international exchange and promotion association for medicine and healthcare (MITG-P-CPAM) (2021) Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours: a multicentre, open-label, randomised controlled trial. Lancet Gastroenterol Hepatol. 6(6):438–447PubMedCrossRef
50.
go back to reference de Rooij T, van Hilst J, van Santvoort H, Boerma D, van den Boezem P, Daams F, van Dam R, Dejong C, van Duyn E, Dijkgraaf M, van Eijck C, Festen S, Gerhards M, Groot Koerkamp B, de Hingh I, Kazemier G, Klaase J, de Kleine R, van Laarhoven C, Luyer M, Patijn G, Steenvoorde P, Suker M, Abu Hilal M, Busch O, Besselink M, Dutch Pancreatic Cancer Group (2019) Minimally invasive versus open distal pancreatectomy (LEOPARD): a multicenter patient-blinded randomized controlled trial. Ann Sur 269(1):2–9CrossRef de Rooij T, van Hilst J, van Santvoort H, Boerma D, van den Boezem P, Daams F, van Dam R, Dejong C, van Duyn E, Dijkgraaf M, van Eijck C, Festen S, Gerhards M, Groot Koerkamp B, de Hingh I, Kazemier G, Klaase J, de Kleine R, van Laarhoven C, Luyer M, Patijn G, Steenvoorde P, Suker M, Abu Hilal M, Busch O, Besselink M, Dutch Pancreatic Cancer Group (2019) Minimally invasive versus open distal pancreatectomy (LEOPARD): a multicenter patient-blinded randomized controlled trial. Ann Sur 269(1):2–9CrossRef
51.
go back to reference van Hilst J, de Rooij T, Klompmaker S, Rawashdeh M, Aleotti F, Al-Sarireh B, Alseidi A, Ateeb Z, Balzano G, Berrevoet F, Björnsson B, Boggi U, Busch OR, Butturini G, Casadei R, Del Chiaro M, Chikhladze S, Cipriani F, van Dam R, Damoli I, van Dieren S, Dokmak S, Edwin B, van Eijck C, Fabre JM, Falconi M, Farges O, Fernández-Cruz L, Forgione A, Frigerio I, Fuks D, Gavazzi F, Gayet B, Giardino A, Groot Koerkamp B, Hackert T, Hassenpflug M, Kabir I, Keck T, Khatkov I, Kusar M, Lombardo C, Marchegiani G, Marshall R, Menon KV, Montorsi M, Orville M, de Pastena M, Pietrabissa A, Poves I, Primrose J, Pugliese R, Ricci C, Roberts K, Røsok B, Sahakyan MA, Sánchez-Cabús S, Sandström P, Scovel L, Solaini L, Soonawalla Z, Souche FR, Sutcliffe RP, Tiberio GA, Tomazic A, Troisi R, Wellner U, White S, Wittel UA, Zerbi A, Bassi C, Besselink MG, Abu Hilal M, European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS) (2019) Minimally invasive versus open distal pancreatectomy for ductal adenocarcinoma (DIPLOMA): a Pan-European propensity score matched study. Ann Surg 269(1):10–17PubMedCrossRef van Hilst J, de Rooij T, Klompmaker S, Rawashdeh M, Aleotti F, Al-Sarireh B, Alseidi A, Ateeb Z, Balzano G, Berrevoet F, Björnsson B, Boggi U, Busch OR, Butturini G, Casadei R, Del Chiaro M, Chikhladze S, Cipriani F, van Dam R, Damoli I, van Dieren S, Dokmak S, Edwin B, van Eijck C, Fabre JM, Falconi M, Farges O, Fernández-Cruz L, Forgione A, Frigerio I, Fuks D, Gavazzi F, Gayet B, Giardino A, Groot Koerkamp B, Hackert T, Hassenpflug M, Kabir I, Keck T, Khatkov I, Kusar M, Lombardo C, Marchegiani G, Marshall R, Menon KV, Montorsi M, Orville M, de Pastena M, Pietrabissa A, Poves I, Primrose J, Pugliese R, Ricci C, Roberts K, Røsok B, Sahakyan MA, Sánchez-Cabús S, Sandström P, Scovel L, Solaini L, Soonawalla Z, Souche FR, Sutcliffe RP, Tiberio GA, Tomazic A, Troisi R, Wellner U, White S, Wittel UA, Zerbi A, Bassi C, Besselink MG, Abu Hilal M, European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS) (2019) Minimally invasive versus open distal pancreatectomy for ductal adenocarcinoma (DIPLOMA): a Pan-European propensity score matched study. Ann Surg 269(1):10–17PubMedCrossRef
52.
go back to reference Liu R, Wakabayashi G, Palanivelu C, Tsung A, Yang K, Goh BKP, Chong CC, Kang CM, Peng C, Kakiashvili E, Han HS, Kim HJ, He J, Lee JH, Takaori K, Marino MV, Wang SN, Guo T, Hackert T, Huang TS, Anusak Y, Fong Y, Nagakawa Y, Shyr YM, Wu YM, Zhao Y (2019) International consensus statement on robotic pancreatic surgery. Hepatobiliary Surg Nutr 8(4):345–360PubMedPubMedCentralCrossRef Liu R, Wakabayashi G, Palanivelu C, Tsung A, Yang K, Goh BKP, Chong CC, Kang CM, Peng C, Kakiashvili E, Han HS, Kim HJ, He J, Lee JH, Takaori K, Marino MV, Wang SN, Guo T, Hackert T, Huang TS, Anusak Y, Fong Y, Nagakawa Y, Shyr YM, Wu YM, Zhao Y (2019) International consensus statement on robotic pancreatic surgery. Hepatobiliary Surg Nutr 8(4):345–360PubMedPubMedCentralCrossRef
53.
go back to reference Loos M, Strobel O, Dietrich M, Mehrabi A, Ramouz A, Al-Saeedi M, Müller-Stich BP, Diener MK, Schneider M, Berchtold C, Feisst M, Hinz U, Mayer P, Giannakis A, Schneider D, Weigand MA, Büchler MW, Hackert T (2021) Hyperamylasemia and acute pancreatitis after pancreatoduodenectomy: two different entities. Surgery 169(2):369–376PubMedCrossRef Loos M, Strobel O, Dietrich M, Mehrabi A, Ramouz A, Al-Saeedi M, Müller-Stich BP, Diener MK, Schneider M, Berchtold C, Feisst M, Hinz U, Mayer P, Giannakis A, Schneider D, Weigand MA, Büchler MW, Hackert T (2021) Hyperamylasemia and acute pancreatitis after pancreatoduodenectomy: two different entities. Surgery 169(2):369–376PubMedCrossRef
54.
go back to reference Nentwich MF, El Gammal AT, Lemcke T, Ghadban T, Bellon E, Melling N, Bachmann K, Reeh M, Uzunoglu FG, Izbicki JR, Bockhorn M (2015) Salvage completion pancreatectomies as damage control for post-pancreatic surgery complications: a single-center retrospective analysis. World J Surg 39(6):1550–1556PubMedCrossRef Nentwich MF, El Gammal AT, Lemcke T, Ghadban T, Bellon E, Melling N, Bachmann K, Reeh M, Uzunoglu FG, Izbicki JR, Bockhorn M (2015) Salvage completion pancreatectomies as damage control for post-pancreatic surgery complications: a single-center retrospective analysis. World J Surg 39(6):1550–1556PubMedCrossRef
Metadata
Title
State-of-the-art surgery for pancreatic cancer
Publication date
01-03-2022
Published in
Langenbeck's Archives of Surgery / Issue 2/2022
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-021-02362-y

Other articles of this Issue 2/2022

Langenbeck's Archives of Surgery 2/2022 Go to the issue