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Published in: Langenbeck's Archives of Surgery 4/2021

Open Access 01-06-2021 | Cholecystitis | Original Article

Routine postoperative blood tests fail to reliably predict procedure-related complications after laparoscopic cholecystectomy

Authors: Jens Strohäker, Lisa Wiegand, Christian Beltzer, Alfred Königsrainer, Ruth Ladurner, Robert Bachmann

Published in: Langenbeck's Archives of Surgery | Issue 4/2021

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Abstract

Purpose

Laparoscopic cholecystectomy is a highly standardized surgical procedure with a low risk of complications. However, once complications develop, they can be life-threatening. The aim of this study was to evaluate the value of blood tests on postoperative day one regarding their potential to predict postoperative complications

Methods

A cohort study of 1706 consecutive cholecystectomies performed at a tertiary hospital and teaching facility over a 5-year period between 2014 and 2019.

Results

Patients that had open CCE or conversion CCE were excluded. One thousand five hundred eighty-six patients were included in the final analysis that received a laparoscopic cholecystectomy (CCE). One thousand five hundred twenty-three patients had blood tests on POD 1. Forty-one complications were detected including 14 bile leaks, 2 common bile duct injuries, 13 choledocholithiasis, 9 hematomas, and 2 active bleedings. Bilirubin was elevated in 351 patients on POD 1. A drop of more than 3 mg/dl of hemoglobin was reported in 39 patients. GPT was elevated 3 × above the upper limit in 102 patients. All three tests showed a low sensitivity and specificity in detecting postoperative complications.

Conclusions

Early postoperative blood tests alone show a low specificity in detecting postoperative complications after laparoscopic CCE. Their main benefit appears to be the negative predictive value, when they are normal. Routine blood testing appears to be unnecessary and should be based on the intraoperative diagnosis and postoperative clinical findings.
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Metadata
Title
Routine postoperative blood tests fail to reliably predict procedure-related complications after laparoscopic cholecystectomy
Authors
Jens Strohäker
Lisa Wiegand
Christian Beltzer
Alfred Königsrainer
Ruth Ladurner
Robert Bachmann
Publication date
01-06-2021
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 4/2021
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-021-02115-x

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