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Langenbeck's Archives of Surgery
Published in: Langenbeck's Archives of Surgery 7/2020

01-11-2020 | Colon Cancer | Original Article

The factors related to failure of Enhanced Recovery after Surgery (ERAS) in colon cancer surgery

Authors: Jian-Sheng Chen, Si-Da Sun, Zhi-Sheng Wang, Tian-Hong Cai, Long-Kai Huang, Wen-Xing Sun, Chang-Qing Lin, Jun-Feng Zhou, Jia-Xing Wang, Qing-Liang He

Published in: Langenbeck's Archives of Surgery | Issue 7/2020

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Abstract

Purpose

Enhanced Recovery after Surgery has been proven effective for patients with gastrointestinal cancer. But radical enhanced recovery could also lead to adverse clinical outcomes. Compared with reports on the estimation of successful implementation of enhanced recovery, studies on risk factors of enhanced recovery failure are still lacking.

Methods

A retrospective analysis was carried out on 102 patients in ERAS who underwent elective colon cancer surgery. This study included 102 patients with colon cancer between 2015 and 2019, defining enhanced recovery failure as postoperative length of stay over 10 days, stay in ICU over 24 h after surgery, reoperation, death, or unplanned readmission within 30 days after surgery. Univariate and multivariate analyses were performed to explore potential risk factors of failure.

Results

Aged ≥ 75, open operation, number of drainage tube over 1, re-urethral catheterization, and Clavien-Dindo grade over 2 were associated with ERAS failure, according to univariate analysis. Multivariate analysis showed that age ≥ 75 [OR 7.231; P = 0.009]; open operation (OR 3.599; P = 0.021); and number of drainage tube over 1 (OR 3.202; P = 0.020) were independent risk factors for ERAS failure.

Conclusions

We found age ≥ 75, open operation, and number of drainage tube over 1 are independent risk factors associated with ERAS failure after colon cancer surgery.
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Metadata
Title
The factors related to failure of Enhanced Recovery after Surgery (ERAS) in colon cancer surgery
Authors
Jian-Sheng Chen
Si-Da Sun
Zhi-Sheng Wang
Tian-Hong Cai
Long-Kai Huang
Wen-Xing Sun
Chang-Qing Lin
Jun-Feng Zhou
Jia-Xing Wang
Qing-Liang He
Publication date
01-11-2020
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 7/2020
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-020-01975-z

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