Skip to main content
Top
Published in: Langenbeck's Archives of Surgery 5/2015

01-07-2015 | Review Article

Organisational structure of liver transplantation in the UK

Author: James Neuberger

Published in: Langenbeck's Archives of Surgery | Issue 5/2015

Login to get access

Abstract

Aim

This review aims to outline the delivery of liver transplant services in the UK.

Background

Liver transplantation in the UK is based on seven designated transplant units serving a population of just over 60 million people. Nearly 900 liver transplants were done in 2013/2014.

Process

Potential deceased donors are identified and referred to centrally employed specialist nurses for obtaining family consent and for donor characterisation. Organs are retrieved by a National Organ Retrieval Service, based on seven abdominal and six cardiothoracic retrieval teams providing a 24/7 service which has shown to be capable of retrieving organs from up to ten donors a day. Donated organs are allocated first nationally to those who qualify for super-urgent listing. The next priority is for splitting livers, and if there is no suitable recipient or the liver is not suitable for splitting, then livers are offered first to the local centre; each centre has a designated donor zone, adjusted annually to ensure equity between the number of patients listed and the number of donors. The allocation scheme is being reviewed, and national schemes based on need, utility and benefit are being assessed.

Governance

Outcomes are monitored by National Health Service Blood and Transplant (NHSBT), and if there is a possibility of adverse deviation, then further inquiries are made. Outcomes, both from listing and from transplantation, are published by the centre on the NHSBT website (www.​odt.​nhs.​uk). NHSBT works closely with stakeholders primarily through the advisory groups with clinicians, patients, lay members and professional societies and aims to provide openness and transparency.

Conclusions

The system for organ donation and delivery of liver transplant in the UK has developed and is now providing an effective and efficient service, but there remains room for improvement.
Literature
3.
go back to reference Barber K, Madden S, Allen J, Collett D, Neuberger J, Gimson AE, United Kingdom Liver Transplant Selection and Allocation Working Party (2011) Elective liver transplant mortality: development of a United Kingdom end-stage liver disease score. Transplantation 92:469–476PubMedCrossRef Barber K, Madden S, Allen J, Collett D, Neuberger J, Gimson AE, United Kingdom Liver Transplant Selection and Allocation Working Party (2011) Elective liver transplant mortality: development of a United Kingdom end-stage liver disease score. Transplantation 92:469–476PubMedCrossRef
4.
go back to reference Newsletter Transplant International. Figures on Donation and Transplantation 2012. 18:1.2013 Newsletter Transplant International. Figures on Donation and Transplantation 2012. 18:1.2013
5.
go back to reference Johnson R, Bradbury LL, Martin K, Neuberger J, UK Transplant Registry (2014) Organ donation and transplantation in the UK—the last decade: a report from the UK national transplant registry. Transplantation 97(Suppl 1):S1–S27 Johnson R, Bradbury LL, Martin K, Neuberger J, UK Transplant Registry (2014) Organ donation and transplantation in the UK—the last decade: a report from the UK national transplant registry. Transplantation 97(Suppl 1):S1–S27
6.
go back to reference Neuberger J, Madden S, Collett D (2010) Review of methods for measuring and comparing center performance after organ transplantation. Liver Transpl 16:1119–1128PubMedCrossRef Neuberger J, Madden S, Collett D (2010) Review of methods for measuring and comparing center performance after organ transplantation. Liver Transpl 16:1119–1128PubMedCrossRef
7.
go back to reference Saidi RF, Razavi M, Cosimi AB, Ko DS (2015) Competition in liver transplantation: helpful or harmful? Liver Transpl 21:145–150PubMedCrossRef Saidi RF, Razavi M, Cosimi AB, Ko DS (2015) Competition in liver transplantation: helpful or harmful? Liver Transpl 21:145–150PubMedCrossRef
8.
go back to reference Halldorson JB, Paarsch HJ, Didge JL, Segre AM, Lai J, Roberts JP (2013) Center competition and outcomes following liver transplantation. Liver Transpl 19:96–104PubMedCentralPubMedCrossRef Halldorson JB, Paarsch HJ, Didge JL, Segre AM, Lai J, Roberts JP (2013) Center competition and outcomes following liver transplantation. Liver Transpl 19:96–104PubMedCentralPubMedCrossRef
9.
go back to reference Macomber CW, Shaw JJ, Santry H, Saidi RF, Jabbour N, Tseng JF, Bozorgzadeh A, Shah SA (2012) Center volume and resource consumption in liver transplantation. HPB 14:554–559PubMedCentralPubMedCrossRef Macomber CW, Shaw JJ, Santry H, Saidi RF, Jabbour N, Tseng JF, Bozorgzadeh A, Shah SA (2012) Center volume and resource consumption in liver transplantation. HPB 14:554–559PubMedCentralPubMedCrossRef
10.
go back to reference Guba M (2014) Center volume, competition and outcome in German liver transplant centers. Transp Res 3:6CrossRef Guba M (2014) Center volume, competition and outcome in German liver transplant centers. Transp Res 3:6CrossRef
11.
go back to reference Nijboer A, Ulrich F, Bechstein WO, Schnitzbauer AA (2014) Volume and outcome relation in German liver transplant centers: what lessons can be learned? Transpl Res 3:4CrossRef Nijboer A, Ulrich F, Bechstein WO, Schnitzbauer AA (2014) Volume and outcome relation in German liver transplant centers: what lessons can be learned? Transpl Res 3:4CrossRef
12.
go back to reference Burroughs A, Sabin CA, Rolles K, Delvart V, Karam V, Buckels J et al (2006) 3-month and 12-month mortality after first liver transplant in adults in Europe: predictive models for outcome. Lancet 367:225–232PubMedCrossRef Burroughs A, Sabin CA, Rolles K, Delvart V, Karam V, Buckels J et al (2006) 3-month and 12-month mortality after first liver transplant in adults in Europe: predictive models for outcome. Lancet 367:225–232PubMedCrossRef
13.
go back to reference Roberts JP (2012) Impact of outcomes monitoring on innovation and risk in liver transplantation. Liver Transpl 18(Suppl 2):S59–S63PubMedCrossRef Roberts JP (2012) Impact of outcomes monitoring on innovation and risk in liver transplantation. Liver Transpl 18(Suppl 2):S59–S63PubMedCrossRef
14.
go back to reference Abercassis MM, Burke R, Klintmalm GB, Matas AJ, Merion RM, Millman D, Olthoff K et al (2009) American Society of Transplant Surgeons transplant center outcomes requirements—a threat to innovation. Am J Transplant 9:1279–1286CrossRef Abercassis MM, Burke R, Klintmalm GB, Matas AJ, Merion RM, Millman D, Olthoff K et al (2009) American Society of Transplant Surgeons transplant center outcomes requirements—a threat to innovation. Am J Transplant 9:1279–1286CrossRef
Metadata
Title
Organisational structure of liver transplantation in the UK
Author
James Neuberger
Publication date
01-07-2015
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 5/2015
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-015-1296-9

Other articles of this Issue 5/2015

Langenbeck's Archives of Surgery 5/2015 Go to the issue