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Langenbeck's Archives of Surgery

Published in:

01-04-2012 | Review Article

Chemoprevention of pancreatic cancer—one step closer

Author: Volker Fendrich

Published in: Langenbeck's Archives of Surgery | Issue 4/2012

Abstract

Background

Since for pancreatic cancer the mortality rate approaches the incidence rate with only 1–4% of all patients surviving 5 years, it would be would be of great value to provide chemopreventive treatment for high-risk individuals.

Discussion

The preclinical study of pancreatic intraepithelial neoplasia (PanINs) has recently been made possible by the generation of genetically modified animal models, which recapitulate human PanINs and invasive pancreatic cancer on a genetic and histomorphologic level. Very recently, several groups have reported first evidence of chemoprevention of pancreatic cancer.

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Title: Chemoprevention of pancreatic cancer—one step closer
Author: Volker Fendrich
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: Langenbeck's Archives of Surgery / Issue 4/2012
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-012-0916-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Chemoprevention of pancreatic cancer—one step closer

Abstract

Background

Discussion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Discussion

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