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Langenbeck's Archives of Surgery

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01-09-2007 | Current Concepts in Clinical Surgery

Current concepts in transplant surgery: laparoscopic living donor of the kidney

Authors: Andreas Paul, Jürgen Treckmann, Anja Gallinat, Oliver Witzke, Udo Vester, Christoph E. Broelsch

Published in: Langenbeck's Archives of Surgery | Issue 5/2007

Abstract

Introduction

Living donor kidney transplantation has emerged as an excellent alternative to cadaveric donation since, more than 50 years ago, the first live donor nephrectomy was successfully performed.

Objective

The basic idea of introducing laparoscopy in live donor nephrectomy was to obtain a potential reduction in incision-related morbidity with reduced pain and faster reconvalescence while providing at least the same level of operative security. This paper is focusing on technical aspects, outcome, results, and possible current concerns and advantages of laparoscopic living-related donor nephrectomy.

Conclusion

According to our results and the results available in the literature, laparoscopic living donor nephrectomy is safe when performed with sufficient experience. Postoperative pain is less and recovery is significantly faster.

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Guild WR, Harrison JH, Merrill JP, Murray J (1955–1956) Successful homotransplantation of the kidney in an identical twin. Trans Am Clin Climatol Assoc 67:167–173

Terasaki PI, Cecka JM, Gjertson DW, Takemoto S (1995) High survival rates of kidney transplants from spousal and living unrelated donors. N Engl J Med 333(6):333–336PubMedCrossRef

Matas AJ, Payne WD, Sutherland DE, Humar A, Gruessner RW, Kandaswamy R, Dunn DL, Gillingham KJ, Najarian (2001) 2,500 living donor kidney transplants: a single-center experience. Ann Surg 234(2):149–164PubMedCrossRef

Handschin AE, Weber M, Demartines N, Clavien PA (2003) Laparoscopic donor nephrectomy. Br J Surg 90(11):1323–1332PubMedCrossRef

Tooher RL, Rao MM, Scott DF, Wall DR, Francis DM, Bridgewater FH, Maddern GJ (2004) A systematic review of laparoscopic live-donor nephrectomy. Transplantation 15;78(3):404–414CrossRef

Merlin TL, Scott DF, Rao MM, Wall DR, Francis DM, Bridgewater FH, Maddern GJ (2000) The safety and efficacy of laparoscopic live donor nephrectomy: a systematic review. Transplantation 70(12):1659–1666PubMedCrossRef

Ratner LE, Ciseck LJ, Moore RG, Cigarroa FG, Kaufman HS, Kavoussi LR (1995) Laparoscopic live donor nephrectomy. Transplantation 60(9):1047–1049PubMed

Rassweiler JJ, Wiesel M, Carl S, Drehmer I, Jurgowski W, Staehler G (2001) Laparoscopic liver donor nephrectomy. Personal experiences and review of the literature. Urologe A 40(6):485–492PubMedCrossRef

Wadstrom J, Lindstrom P (2002) Hand-assisted retroperitoneoscopic living-donor nephrectomy: initial 10 cases. Transplantation 73(11):1839–1840PubMedCrossRef

10.

Ng CS, Abreu SC, Abou El-Fettouh HI, Kaouk JH, Desai MM, Goldfarb DA, Gill IS (2004) Right retroperitoneal versus left transperitoneal laparoscopic live donor nephrectomy. Urology 63(5):857–861PubMedCrossRef

11.

Kok NF, Weimar W, Alwayn IP, Ijzermans JN (2006) The current practice of live donor nephrectomy in Europe. Transplantation 82(7):892–897PubMedCrossRef

12.

Wolf JS Jr, Tchetgen MB, Merion RM (1998) Hand-assisted laparoscopic live donor nephrectomy. Urology 52(5):885–887PubMedCrossRef

13.

Lindstrom P, Haggman M, Wadstrom J (2002) Hand-assisted laparoscopic surgery (HALS) for live donor nephrectomy is more time- and cost-effective than standard laparoscopic nephrectomy. Surg Endosc 16(3):422–425PubMedCrossRef

14.

Stoffel F, Forster TH, Steiger J, Gasser TC, Sulser T (2002) Manually-assisted laparoscopic donor nephrectomy. Urologe A 41(3):258–262PubMedCrossRef

15.

Ruiz-Deya G, Cheng S, Palmer E, Thomas R, Slakey D (2001) Open donor, laparoscopic donor and hand assisted laparoscopic donor nephrectomy: a comparison of outcomes. J Urol 166(4):1270–1273, (Oct); discussion 1273–1274. Comment in: J Urol 2002 168(1):199PubMedCrossRef

16.

Slakey DP, Wood JC, Hender D, Thomas R, Cheng S (1999) Laparoscopic living donor nephrectomy: advantages of the hand-assisted method. Transplantation 68(4):581–583PubMedCrossRef

17.

Wolf JS Jr, Merion RM, Leichtman AB, Campbell DA Jr, Magee JC, Punch JD, Turcotte JG, Konnak JW (2001) Randomized controlled trial of hand-assisted laparoscopic versus open surgical live donor nephrectomy. Transplantation 72(2):284–290PubMedCrossRef

18.

Simforoosh N, Basiri A, Tabibi A, Shakhssalim N, Hosseini Moghaddam SM (2005) Comparison of laparoscopic and open donor nephrectomy: a randomized controlled trial. BJU Int 95(6):851–855PubMedCrossRef

19.

Oyen O, Andersen M, Mathisen L, Kvarstein G, Edwin B, Line PD, Scholz T, Pfeffer PF (2005) Laparoscopic versus open living-donor nephrectomy: experiences from a prospective, randomized, single-center study focusing on donor safety. Transplantation 79(9):1236–1240PubMedCrossRef

20.

Kok NF, Lind MY, Hansson BM, Pilzecker D, Mertens zur Borg IR, Knipscheer BC, Hazebroek EJ, Dooper IM, Weimar W, Hop WC, Adang EM, van der Wilt GJ, Bonjer HJ, van der Vliet JA, IJzermans JN (2006) Comparison of laparoscopic and mini incision open donor nephrectomy: single blind, randomised controlled clinical trial. BMJ 333(7561):221PubMedCrossRef

21.

Matas AJ, Bartlett ST, Leichtman AB, Delmonico FL (2003) Morbidity and mortality after living kidney donation, 1999–2001: survey of United States transplant centers. Am J Transplant 3(7):830–834PubMedCrossRef

22.

Gorodner V, Horgan S, Galvani C, Manzelli A, Oberholzer J, Sankary H, Testa G, Benedetti E (2006) Routine left robotic-assisted laparoscopic donor nephrectomy is safe and effective regardless of the presence of vascular anomalies. Transpl Int 19(8):636–640PubMedCrossRef

23.

Talamini MA, Chapman S, Horgan S, Melvin WS, The Academic Robotics Group(2003) A prospective analysis of 211 robotic-assisted surgical procedures. Surg Endosc 17(10):1521–1524PubMedCrossRef

24.

Bolte SL, Chin LT, Moon TD, D’Alessandro AM, Nakada SY, Becker YT, Hedican SP (2006) Maintaining urine production and early allograft function during laparoscopic donor nephrectomy. Urology 68(4):747–750PubMedCrossRef

25.

Ramani AP, Gill IS, Steinberg AP, Abreu SC, Kilciler M, Kaouk J, Desai M (2005) Impact of intraoperative heparin on laparoscopic donor nephrectomy. J Urol 174(1):226–228PubMedCrossRef

26.

Friedman AL, Peters TG, Jones KW, Boulware LE, Ratner LE (2006) Fatal and nonfatal hemorrhagic complications of living kidney donation. Ann Surg 243(1):126–130PubMedCrossRef

27.

Martay K, Dembo G, Vater Y, Charpentier K, Levy A, Bakthavatsalam R, Freund PR (2003) Unexpected surgical difficulties leading to hemorrhage and gas embolus during laparoscopic donor nephrectomy: a case report. Can J Anaesth 50(9):891–894PubMedCrossRef

28.

Boghossian T, Henri M, Dube S, Bendavid Y, Morin M (2005) Laparoscopic nephrectomy donor death due to cerebral gas embolism in a specialized transplant center: risk zero does not exist. Transplantation 79(2):258–259PubMedCrossRef

29.

Buell JF, Edye M, Johnson M, Li C, Koffron A, Cho E, Kuo P, Johnson L, Hanaway M, Potter SR, Bruce DS, Cronin DC, Newell KA, Leventhal J, Jacobs S, Woodle ES, Bartlett ST, Flowers JL (2001) Are concerns over right laparoscopic donor nephrectomy unwarranted? Ann Surg 233(5):645–651PubMedCrossRef

30.

Mandal AK, Cohen C, Montgomery RA, Kavoussi LR, Ratner LE (2001) Should the indications for laparascopic live donor nephrectomy of the right kidney be the same as for the open procedure? Anomalous left renal vasculature is not a contraindiction to laparoscopic left donor nephrectomy. Transplantation 71(5):660–664PubMedCrossRef

31.

Swartz DE, Cho E, Flowers JL, Dunkin BJ, Ramey JR, Bartlett ST, Jarrell B, Jacobs SC (2001) Laparoscopic right donor nephrectomy: technique and comparison with left nephrectomy. Surg Endosc 15(12):1390–1394PubMed

32.

Buell JF, Abreu SC, Hanaway MJ, Ng CS, Kaouk JH, Clippard M, Zaki S, Goldfarb DA, Woodle ES, Gill IS (2004) Right donor nephrectomy: a comparison of hand-assisted transperitoneal and retroperitoneal laparoscopic approaches. Transplantation 77(4):521–525PubMedCrossRef

33.

Sampaio FJ, Passos MA (1992) Renal arteries: anatomic study for surgical and radiological practice. Surg Radiol Anat 14(2):113–117PubMedCrossRef

34.

Giessing M, Deger S, Ebeling V, Schonberger B, Roigas J, Kroencke TJ, Turk I (2003) Laparoscopic living donor nephrectomy of kidneys with multiple renal vessels. Urologe A 42(2):225–232PubMed

35.

Hsu TH, Su LM, Ratner LE, Trock BJ, Kavoussi LR (2003) Impact of renal artery multiplicity on outcomes of renal donors and recipients in laparoscopic donor nephrectomy. Urology 61(2):323–327PubMedCrossRef

36.

Oh HK, Hawasli A, Cousins G (2003) Management of renal allografts with multiple renal arteries resulting from laparoscopic living donor nephrectomy. Clin Transplant 17(4):353–357PubMedCrossRef

37.

Carter JT, Freise CE, McTaggart RA, Mahanty HD, Kang SM, Chan SH, Feng S, Roberts JP, Posselt AM (2005) Laparoscopic procurement of kidneys with multiple renal arteries is associated with increased ureteral complications in the recipient. Am J Transplant 5(6):1312–1318PubMedCrossRef

38.

Lindberg F, Bergqvist D, Bjorck M, Rasmussen I (2003) Renal hemodynamics during carbon dioxide pneumoperitoneum: an experimental study in pigs. Surg Endosc 17(3):480–484PubMedCrossRef

39.

Jacobs SC, Cho E, Dunkin BJ, Flowers JL, Schweitzer E, Cangro C, Fink J, Farney A, Philosophe B, Jarrell B, Bartlett ST (2000) Laparoscopic live donor nephrectomy: the University of Maryland 3-year experience. J Urol 164(5):1494–1499PubMedCrossRef

40.

Leventhal JR, Deeik RK, Joehl RJ, Rege RV, Herman CH, Fryer JP, Kaufman D, Abecassis M, Stuart F (2000) Laparoscopic live donor nephrectomy-is it safe? Transplantation 70(4):602–606PubMedCrossRef

41.

Rawlins MC, Hefty TL, Brown SL, Biehl TR (2002) Learning laparoscopic donor nephrectomy safely: a report on 100 cases. Arch Surg 137(5):531–534, (discussion, 534–535)PubMedCrossRef

42.

Troppmann C, McBride MA, Baker TJ, Perez RV (2005) Laparoscopic live donor nephrectomy: a risk factor for delayed function and ejection in pediatric kidney recipients? A UNOS analysis. Am J Transplant 5(1):175–182PubMedCrossRef

43.

Kok NF, Alwayn IP, Schouten O, Tran KT, Weimar W, Ijzermans JN (2006) Mini-incision open donor nephrectomy as an alternative to classic lumbotomy: evolution of the open approach. Transpl Int 19(6):500–505PubMedCrossRef

44.

Firoozfard B, Christensen T, Kristensen JK, Mogensen S, Kehlet H (2003) Fast-track open transperitoneal nephrectomy. Scand J Urol Nephrol 37(4):305–308PubMedCrossRef

45.

Ratner LE, Buell JF, Kuo PC (2000) Laparoscopic donor nephrectomy: pro. Transplantation 70(10):1544–1546PubMedCrossRef

46.

Schweitzer EJ, Wilson J, Jacobs S, Machan CH, Philosophe B, Farney A, Colonna J, Jarrell BE, Bartlett ST (2000) Increased rates of donation with laparoscopic donor nephrectomy. Ann Surg 232(3):392–400PubMedCrossRef

47.

Finelli FC, Gongora E, Sasaki TM, Light J (2001) A survey: the prevalence of laparoscopic donor nephrectomy at large U.S. transplant centers. Transplantation 71(12):1862–1864PubMedCrossRef

Title: Current concepts in transplant surgery: laparoscopic living donor of the kidney
Authors: Andreas Paul
Jürgen Treckmann
Anja Gallinat
Oliver Witzke
Udo Vester
Christoph E. Broelsch
Publication date: 01-09-2007
Publisher: Springer-Verlag
Published in: Langenbeck's Archives of Surgery / Issue 5/2007
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-007-0192-3

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Current concepts in transplant surgery: laparoscopic living donor of the kidney

Abstract

Introduction

Objective

Conclusion

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Abstract

Introduction

Objective

Conclusion

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