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Open Access 01-05-2020 | Insulins | Original Article

Males and females exhibit similar muscle glycogen recovery with varied recovery food sources

Published in: European Journal of Applied Physiology | Issue 5/2020

Abstract

Purpose

Research has elucidated the impact of post-exercise carbohydrate nutrition and environmental conditions on muscle glycogen re-synthesis. However, research has minimally considered the implications of glycogen recovery in females and has mostly focused on commercial sport nutrition products. The purpose of this study was to determine the effects of varied mixed macronutrient feedings on glycogen recovery and subsequent exercise performance in both sexes.

Methods

Males (n = 8) and females (n = 8) participated in a crossover study. Subjects completed a 90-min cycling glycogen depletion trial, then rested for 4 h. Two carbohydrate feedings (1.6 g kg⁻¹) of either sport supplements or potato-based products were delivered at 0 and 2 h post-exercise. Muscle biopsies (glycogen) and blood samples (glucose, insulin) were collected during the recovery. Afterwards, subjects completed a 20 km cycling time trial.

Results

There was no difference between sexes or trials for glycogen recovery rates (male: 7.9 ± 2.7, female: 8.2 ± 2.7, potato-based: 8.0 ± 2.5, sport supplement: 8.1 ± 3.1 mM kg wet wt⁻¹ h⁻¹, p > 0.05). Time trial performance was not different between diets (38.3 ± 4.4 and 37.8 ± 3.9 min for potato and sport supplement, respectively, p > 0.05).

Conclusions

These results indicate that food items, such as potato-based products, can be as effective as commercially marketed sports supplements when developing glycogen recovery oriented menus and that absolute carbohydrate dose feedings (g kg⁻¹) can be effectively applied to both males and females.

Ahlborg B, Bergstrom J, Edelund L, Hultman E (1967) Muscle glycogen and muscle electrolytes during prolonged physical exercise. Acta Physiol 70:129–142

American College of Sports Medicine (2013) ACSM’s guidelines for exercise testing and prescription. Lippincott Williams & Wilkins, Philadelphia

Baranauskas M, Stukas R, Tubelis L et al (2015) Nutritional habits among high-performance endurance athletes. Medicina 51:351–362PubMed

Bergstrom J (1975) Percutaneous needle biopsy in physiological and clinical research. Scand J Clin Lab Investig 35:609–616

Bergstrom J, Hermansen L, Hultman E, Saltin B (1967) Diet, muscle glycogen, and physical performance. Acta Physiol 71:140–150

Black KE, Baker DF, Sims ST (2019) Nutritional needs of the female athlete: risk and prevention of low energy availability. Strength Cond J. https://doi.org/10.1519/ssc.0000000000000464 CrossRef

Blom P, Hostmark AT, Vaage O, Kardel KR, Maehlum S (1987) Effect of different post-exercise sugar diets on the rate of muscle glycogen synthesis. Med Sci Sports Exerc 19:491–496PubMed

Burke LM, Collier GR, Hargreaves M (1993) Muscle glycogen storage after prolonged exercise: effect of the glycemic index of carbohydrate feedings. J Appl Physiol 75:1019–1023PubMed

Burke LM, Cox GR, Cummings NK, Desbrow B (2001) Guidelines for daily carbohydrate intake: do athletes achieve them? Sports Med 31:267–299PubMed

Cramer MJ, Dumke CL, Hailes WS, Cuddy JS, Ruby BC (2015) Postexercise glycogen recovery and exercise performance is not significantly different between fast food and sport supplements. Int J Sport Nutr Exerc Metab 25:448–455PubMed

De Bock K (2005) Exercise in the fasted state facilitates fibre type-specific intramyocellular lipid breakdown and stimulates glycogen resynthesis in humans. J Physiol 564:649–660PubMedPubMedCentral

de Oliveira OM, Anderson C, Dearborn J et al (2018) Dietary diversity: implications for obesity prevention in adult populations: a science advisory from the American Heart Association. Circulation 138:e160–e168

Devries MC (2016) Sex-based differences in endurance exercise muscle metabolism: impact on exercise and nutritional strategies to optimize health and performance in women. Exp Physiol 101:243–249PubMed

Devries MC, Hamedeh MJ, Phillips SA, Tarnopolsky MA (2006) Am J Physiol Regul Integr Comp Physiol 291:R1120–R1128PubMed

Evans WJ, Phinney SD, Young VR (1982) Suction applied to a muscle biopsy maximizes sample size. Med Sci Sports Exerc 14:101–102PubMed

Frost GS, Brynes AE, Dhillo WS, Bloom SR, McBurney MI (2003) The effects of fiber enrichment of pasta and fat content on gastric emptying, GLP-1, glucose, and insulin responses to a meal. Eur J Clin Nutr 57:293–298PubMed

Goldman HI, Becklake MR (1959) Respiratory function tests; normal values at median altitudes and the prediction of normal results. Am J Tuberc 79:457–467

Harger-Domitrovich SG, McClaughry AE, Gaskill SE, Ruby BC (2007) Exogenous carbohydrate spares muscle glycogen in men and women during 10 h of exercise. Med Sci Sports Exerc 39:2171–2179PubMed

Hellström PM, Grybäck P, Jacobsson H (2006) The physiology of gastric emptying. Best Pract Res Clin Anaesthesiol 20:397–407PubMed

Heneghan C, Howick J, O'Neill B et al (2012) The evidence underpinning sports performance products: a systematic assessment. BMJ Open 2:e001702PubMedPubMedCentral

Hoyt RW, Jones TE, Stein TP et al (1991) Doubly labeled water measurement of human energy expenditure during strenuous exercise. J Appl Physiol 71:16–22PubMed

Ivy JL, Goforth HJ, Damon BM, McCauley TR, Parson EC, Price TB (2002) Early postexercise muscle glycogen recovery is enhanced with a carbohydrate-protein supplement. J Appl Physiol 93:1337–1344PubMed

Ivy JL, Katz AL, Cutler CL, Sherman WM, Coyle EF (1988a) Muscle glycogen synthesis after exercise: effect of time of carbohydrate ingestion. J Appl Physiol 64:1480–1485PubMed

Ivy JL, Lee MC, Brozinick JJ, Reed MJ (1988b) Muscle glycogen storage after different amounts of carbohydrate ingestion. J Appl Physiol 65:2018–2023PubMed

James AP, Lorraine M, Cullen D et al (2001) Muscle glycogen supercompensation: absence of a gender-related difference. Eur J Appl Physiol 86:533–538

Jentjens RLPJ, van Loon LJC, Mann CH, Wagenmakers AJM, Jeukendrup AE (2001) Addition of protein and amino acids to carbohydrates does not enhance postexercise muscle glycogen synthesis. J Appl Physiol 91:839–846PubMed

Karp JR, Johnston JD, Tecklenburg S, Mickleborough TD, Fly AD, Stager JM (2006) Chocolate milk as a post-exercise recovery aid. Int J Sport Nutr Exerc Metab 16:78–91PubMed

Kions B, Raben AB, Valeur AK (1990) Benefit of dietary simple carbohydrates on the early post-exercise muscle glycogen repletion in male athletes. Med Sci Sports Exerc 22:S88

Kissileff HR, Carretta JC, Geliebter A, Pi-Sunyer FX (2003) Cholecystokinin and stomach distension combine to reduce food intake in humans. Am J Physiol Regul Integr Comp Physiol 285:R99–R998

Lundsgaard A, Kiens B (2014) Gender differences in skeletal muscle substrate metabolism: molecular mechanisms and insulin sensitivity. Front Endocrinol 5:195

Lunn WR, Pasiakos SM, Colletto MR et al (2012) Chocolate milk and endurance exercise recovery: protein balance, glycogen, and performance. Med Sci Sports Exerc 44:682–691PubMed

Macdonald IA (1996) Physiological regulation of gastric emptying and glucose absorption. Diabet Med 13:S11–S15PubMed

Masson G, Lamarche B (2016) Many non-elite multisport endurance athletes do not meet sports nutrition recommendations for carbohydrates. Appl Physiol Nutr Metab 41:728–734PubMed

Naperalsky M, Ruby B, Slivka D (2010) Environmental temperature and glycogen resynthesis. Int J Sports Med 31:561–566PubMed

Paul DR, Mulroy SM, Horner JA, Jacobs KA, Lamb DR (2001) Carbohydrate-loading during the follicular phase of the menstrual cycle: effects on muscle glycogen and exercise performance. Int J Sports Nutr Exerc Metab 22:430–441

Price TB, Rothman DL, Taylor R, Avison MJ, Shulman GI, Shulman RG (1994) Human muscle glycogen resynthesis after exercise: insulin-dependent and -independent phases. J Appl Physiol 76:104–111PubMed

Pritchett K, Bishop P, Pritchett R, Green M, Katica C (2009) Acute effects of chocolate milk and a commercial recovery beverage on postexercise recovery indices and endurance cycling performance. Appl Physiol Nutr Metab 34:1017–1022PubMed

Reed MJ, Brozinick JJ, Lee MC, Ivy JL (1989) Muscle glycogen storage postexercise: effect of mode of carbohydrate administration. J Appl Physiol 66:720–726PubMed

Rehrer NJ, McLay-Cooke RT, Sims ST (2017) Nutritional strategies and sex hormone interactions in women. In: Hackney AC (ed) Sex hormones, exercise and women. Springer, Cham, pp 87–112

Reinert A, Slivka D, Cuddy J, Ruby B (2009) Glycogen synthesis after road cycling in the fed state. Int J Sports Med 30:545–549PubMed

Riddell MC, Partington SL, Stupka N, Armstrong D, Rennie C, Tarnopolsky MA (2003) Substrate utilization during exercise performed with and without glucose ingestion in female and male endurance-trained athletes. Int J Sports Nutr Exerc Metab 13:407–421

Rietschier H, Henagan T, Earnest C, Baker B, Cortez C, Stewart L (2011) Sun-dried raisins are a cost-effective alternative to sports jelly beans in prolonged cycling. J Strength Cond Res 25:3150–3156PubMedPubMedCentral

Roepstorff C, Steffensen CH, Stallknecht B, Kanstrup I, Richter EA, Kiens B (2002) Gender differences in substrate utilization during submaximal exercise in endurance-trained subjects. Am J Physiol 282:E435

Ruby BC, Robergs RA, Waters DL, Burge M, Mermier CM (1997) Effects of acute estrogen replacement on substrate utilization in amenorrheic females. Med Sci Sports Exerc 29:1160–1169PubMed

Ruby BC, Gaskill SE, Slivka D, Harger SG (2005) Addition of a fenugreek extract to glucose feedings increases muscle glycogen resynthesis after exercise. Amino Acids 28:71–76PubMed

Ruby BC, Coggan AR, Zderic TW (2002a) Gender differences in glucose kinetics and substrate oxidation during exercise near the lactate threshold. J Appl Physiol 92:1125–1132PubMed

Ruby BC, Shriver TC, Zderic TW, Sharkey BJ, Burks C, Tysk S (2002b) Total energy expenditure during arduous wildfire suppression. Med Sci Sports Exerc 34:1048–1054PubMed

Shriver LH, Betts NM, Wollenberg G (2013) Dietary intakes and eating habits of college athletes: are female college athletes following the current sports nutrition standards? J Am Coll Health 61:10–16PubMed

Slivka D, Tucker T, Cuddy J, Hailes W, Ruby B (2012) Local heat application enhances glycogenesis. Appl Physiol Nutr Metab 37:247–251PubMed

Slivka D, Heesch M, Dumke C, Cuddy J, Hailes W, Ruby B (2013) Effects of post-exercise recovery in a cold environment on muscle glycogen, PGC-1α, and downstream transcription factors. Cryobiology 66:250–255PubMed

Tarnopolsky M, Ruby B (2001) Sex differences in carbohydrate metabolism. Curr Opin Clin Nutr Metab Care 4:521–526PubMed

Tarnopolsky MA, Bosman M, Macdonald JR, Vandeputte D, Martin J, Roy BD (1997) Postexercise protein-carbohydrate and carbohydrate supplements increase muscle glycogen in men and women. J Appl Physiol 83:1877–1883PubMed

Tarnopolsky MA, Zawada C, Richmond LB et al (2001) Gender differences in carbohydrate loading are related to energy intake. J Appl Physiol 91:225–230PubMed

Tarnopolsky MA (2008) Sex differences in exercise metabolism and the role of 17-beta estradiol. Med Sci Sports Exerc 40:648–654PubMed

Thomas K, Morris P, Stevenson E (2009) Improved endurance capacity following chocolate milk consumption compared with 2 commercially available sport drinks. Appl Physiol Nutr Metab 34:78–82PubMed

Tucker TJ, Slivka DR, Cuddy JS, Hailes WS, Ruby BC (2012) Effect of local cold application on glycogen recovery. J Sport Med Phys Fit 52:158–164

van Loon LJC, Saris WHM, Kruijshoop M, Wagenmakers AJM (2000) Maximizing postexercise muscle glycogen synthesis: carbohydrate supplementation and the application of amino acid or protein hydrolysate mixtures. Am J Clin Nutr 72:106–111PubMed

Vincent R, Roberts A, Frier M, Perkins AC, MacDonald IA, Spiller RC (1995) Effect of bran particle size on gastric emptying and small bowel transit in humans: a scintigraphic study. Gut 37:216–219PubMedPubMedCentral

Walker JL, Heigenhauser JF, Hultman E, Spriet LL (2000) Dietary carbohydrate, muscle glycogen content, and endurance performance in well-trained women. J Appl Physiol 88:2151–2158PubMed

West DW, Burd NA, Churchward-Venne TA, Camera DM, Mitchell CJ, Baker SK, Hawley JA, Coffey VG, Phillips SM (2012) Sex-based comparisons of myofibrillar protein synthesis after resistance exercise in the fed state. J Appl Physiol 112:1805–1813PubMed

Zachwieja JJ, Costill DL, Pascoe DD, Robergs RA, Fink WJ (1991) Influence of muscle glycogen depletion on the rate of resynthesis. Med Sci Sports Exerc 23:44–48PubMed

Zawadski KM, Yaspelkis BB, Ivy JL (1992) Carbohydrate-protein complex increases the rate of muscle glycogen storage after exercise. J Appl Physiol 72:1854–1859

Zytnick D, Park S, Onufrak SJ, Kingsley BS, Sherry B (2015) Knowledge of sugar content of sports drinks is not associated with sports drink consumption. Am J Health Promot 30:101–108PubMed

Title: Males and females exhibit similar muscle glycogen recovery with varied recovery food sources
Publication date: 01-05-2020
Keywords: Insulins
Insulins
Published in: European Journal of Applied Physiology / Issue 5/2020
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-020-04352-2

ACC 2024 Congress

Springer Medicine

Males and females exhibit similar muscle glycogen recovery with varied recovery food sources

Abstract

Purpose

Methods

Results

Conclusions

ACC 2024 Congress

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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