Skip to main content
Top
Published in: International Archives of Occupational and Environmental Health 4/2011

01-04-2011 | Original Article

Occupational contact allergy in the building trade in Germany: influence of preventive measures and changing exposure

Authors: Johannes Geier, Andrea Krautheim, Wolfgang Uter, Holger Lessmann, Axel Schnuch

Published in: International Archives of Occupational and Environmental Health | Issue 4/2011

Login to get access

Abstract

Purpose

Since 1993, assiduous efforts have been made in Germany to lower the incidence of allergic cement dermatitis by reducing the content of hexavalent chromium (Cr VI). Usage of epoxy resin systems has considerably increased in the building trade in the same period. We analysed data of the Information Network of Departments of Dermatology (IVDK) to evaluate the influence of these changing occupational exposures on frequencies of sensitization.

Methods

IVDK data of 1,153 men working in the building trade (bricklayers, tile setters etc.) presenting with occupational skin disease in the years 1994–2008 were analysed, taking into consideration not only the year of patch testing, but also beginning and duration of work in the building trade.

Results

While contact sensitization to chromate decreased from 43.1 to 29.0%, sensitization to epoxy resin increased from 8.4 to 12.4%. Logistic regression analysis revealed that, compared to those who had already worked before 1994, patients having started to work in building trade after 1999 had a significantly decreased risk of chromate sensitization (odds ratio 0.42) and a significantly increased risk of sensitization to epoxy resin (odds ratio 2.79). Additionally, risk of thiuram sensitization increased with the duration of employment.

Conclusion

Our data confirm that reducing Cr VI content of cement is useful in preventing allergic cement eczema, as previously found in Scandinavia. In contrast, the increasing prevalence of contact sensitization to epoxy resin components in the building trade is alarming. Preventive measures, which have already been implemented, have to be enforced.
Literature
go back to reference Anonymus (1993) Technische Regel für Gefahrstoffe (TRGS) 613 „Ersatzstoffe, Ersatzverfahren und Verwendungsbeschränkungen für chromathaltige Zemente und chromathaltige zementhaltige Zubereitungen”. Bundesarbeitsblatt (BArbBl) 4:63 Anonymus (1993) Technische Regel für Gefahrstoffe (TRGS) 613 „Ersatzstoffe, Ersatzverfahren und Verwendungsbeschränkungen für chromathaltige Zemente und chromathaltige zementhaltige Zubereitungen”. Bundesarbeitsblatt (BArbBl) 4:63
go back to reference Anonymus (2002) Technische Regel für Gefahrstoffe (TRGS) 613 „Ersatzstoffe, Ersatzverfahren und Verwendungsbeschränkungen für chromathaltige Zemente und chromathaltige zementhaltige Zubereitungen” Bundesarbeitsblatt (BArbBl) 10:72 Anonymus (2002) Technische Regel für Gefahrstoffe (TRGS) 613 „Ersatzstoffe, Ersatzverfahren und Verwendungsbeschränkungen für chromathaltige Zemente und chromathaltige zementhaltige Zubereitungen” Bundesarbeitsblatt (BArbBl) 10:72
go back to reference Anonymus (2003) Directive 2003/53/EC of the European Parliament and of the Council of 18 June 2003 amending for the 26th time Council Directive 76/769/EEC relating to restrictions on the marketing and use of certain dangerous substances and preparations (nonylphenol, nonylphenol ethoxylate and cement). Off J Eur Union L 178/24, 17.07.2003 Anonymus (2003) Directive 2003/53/EC of the European Parliament and of the Council of 18 June 2003 amending for the 26th time Council Directive 76/769/EEC relating to restrictions on the marketing and use of certain dangerous substances and preparations (nonylphenol, nonylphenol ethoxylate and cement). Off J Eur Union L 178/24, 17.07.2003
go back to reference Avnstorp C (1989) Prevalence of cement eczema in Denmark before and since addition of ferrous sulfate to Danish cement. Acta Derm Venereol (Stockh) 69:151–155 Avnstorp C (1989) Prevalence of cement eczema in Denmark before and since addition of ferrous sulfate to Danish cement. Acta Derm Venereol (Stockh) 69:151–155
go back to reference Avnstorp C (1991) Risk factors for cement eczema. Contact Dermat 25:81–88CrossRef Avnstorp C (1991) Risk factors for cement eczema. Contact Dermat 25:81–88CrossRef
go back to reference Avnstorp C (1992) Cement eczema—an epidemiological intervention study. Acta Derm Venereol (Stockh) Suppl 179:1–22 Avnstorp C (1992) Cement eczema—an epidemiological intervention study. Acta Derm Venereol (Stockh) Suppl 179:1–22
go back to reference Bock M, Schmidt A, Bruckner T, Diepgen TL (2003) Occupational skin disease in the construction industry. Br J Dermatol 149:1165–1171CrossRef Bock M, Schmidt A, Bruckner T, Diepgen TL (2003) Occupational skin disease in the construction industry. Br J Dermatol 149:1165–1171CrossRef
go back to reference Bock M, Schmidt A, Bruckner T, Diepgen TL (2004) Entwicklung der chromatallergie in der deutschen bauwirtschaft. Hautarzt 55:460–464CrossRef Bock M, Schmidt A, Bruckner T, Diepgen TL (2004) Entwicklung der chromatallergie in der deutschen bauwirtschaft. Hautarzt 55:460–464CrossRef
go back to reference Condé-Salazar L, Guimaraens D, Villegas C, Romero A, Gonzalez MA (1995) Occupational allergic contact dermatitis in construction workers. Contact Dermat 33:226–230CrossRef Condé-Salazar L, Guimaraens D, Villegas C, Romero A, Gonzalez MA (1995) Occupational allergic contact dermatitis in construction workers. Contact Dermat 33:226–230CrossRef
go back to reference Fisher AA (1986) Contact dermatitis, 3rd edition, Lea and Febiger Philadelphia, pp 500, 566–569, 762–772 Fisher AA (1986) Contact dermatitis, 3rd edition, Lea and Febiger Philadelphia, pp 500, 566–569, 762–772
go back to reference Fregert S, Gruvberger B, Sandahl E (1979) Reduction of chromate in cement by iron sulfate. Contact Dermat 5:39–42CrossRef Fregert S, Gruvberger B, Sandahl E (1979) Reduction of chromate in cement by iron sulfate. Contact Dermat 5:39–42CrossRef
go back to reference Geier J, Schnuch A (1995) A comparison of contact allergies among construction and non-construction workers attending contact dermatitis clinics in Germany. Results of the IVDK from November 1989 until July 1993. Am J Contact Dermat 6:86–94CrossRef Geier J, Schnuch A (1995) A comparison of contact allergies among construction and non-construction workers attending contact dermatitis clinics in Germany. Results of the IVDK from November 1989 until July 1993. Am J Contact Dermat 6:86–94CrossRef
go back to reference Geier J, Schnuch A (1998) Kontaktallergien im Bau-Hauptgewerbe. Eine Auswertung der Daten des Informationsverbunds Dermatologischer Kliniken (IVDK) 1994–1996. Derm Beruf Umwelt 46:109–114 Geier J, Schnuch A (1998) Kontaktallergien im Bau-Hauptgewerbe. Eine Auswertung der Daten des Informationsverbunds Dermatologischer Kliniken (IVDK) 1994–1996. Derm Beruf Umwelt 46:109–114
go back to reference Geier J, Lessmann H, Hillen U, Jappe U, Dickel H, Koch P, Frosch PJ, Schnuch A, Uter W (2004) An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002. Contact Dermat 51:263–272CrossRef Geier J, Lessmann H, Hillen U, Jappe U, Dickel H, Koch P, Frosch PJ, Schnuch A, Uter W (2004) An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002. Contact Dermat 51:263–272CrossRef
go back to reference Kluger N (2007) Erfolgsstory: Maurerkrätze geht zurück. 10 Jahre chromatarmer Zement in Deutschland. BG BAU aktuell 4/2007: 16 Kluger N (2007) Erfolgsstory: Maurerkrätze geht zurück. 10 Jahre chromatarmer Zement in Deutschland. BG BAU aktuell 4/2007: 16
go back to reference Roto P, Sainio H, Reunala T, Laippala T (1996) Addition of ferrous sulfate to cement and risk of chromium dermatitis among construction workers. Contact Dermat 34:43–50CrossRef Roto P, Sainio H, Reunala T, Laippala T (1996) Addition of ferrous sulfate to cement and risk of chromium dermatitis among construction workers. Contact Dermat 34:43–50CrossRef
go back to reference Rühl R, Kluger N (1995) Handbuch der Bau-Chemikalien. Ecomed Verlag, Landsberg am Lech. Chapter IV-3, p 8 Rühl R, Kluger N (1995) Handbuch der Bau-Chemikalien. Ecomed Verlag, Landsberg am Lech. Chapter IV-3, p 8
go back to reference Schnuch A, Uter W, Lessmann H, Arnold R, Geier J (2008a) Klinische Epidemiologie der Kontaktallergien. Das Register und das Überwachungssystem des Informationsverbundes Dermatologischer Kliniken (IVDK). Allergo J 17:611–624 Schnuch A, Uter W, Lessmann H, Arnold R, Geier J (2008a) Klinische Epidemiologie der Kontaktallergien. Das Register und das Überwachungssystem des Informationsverbundes Dermatologischer Kliniken (IVDK). Allergo J 17:611–624
go back to reference Schnuch A, Aberer W, Agathos M, Becker D, Brasch J, Elsner P, Frosch PJ, Fuchs Th, Geier J, Hillen U, Löffler H, Mahler V, Richter G, Szliska C, für die Deutsche Kontaktallergie-Gruppe (2008b) Durchführung des Epikutantests mit Kontaktallergenen. Leitlinien der Deutschen Dermatologischen Gesellschaft (DDG) und der Deutschen Gesellschaft für Allergie und klinische Immunologie (DGAKI). J Dtsch Dermatol Ges 6:770–775 Schnuch A, Aberer W, Agathos M, Becker D, Brasch J, Elsner P, Frosch PJ, Fuchs Th, Geier J, Hillen U, Löffler H, Mahler V, Richter G, Szliska C, für die Deutsche Kontaktallergie-Gruppe (2008b) Durchführung des Epikutantests mit Kontaktallergenen. Leitlinien der Deutschen Dermatologischen Gesellschaft (DDG) und der Deutschen Gesellschaft für Allergie und klinische Immunologie (DGAKI). J Dtsch Dermatol Ges 6:770–775
go back to reference Struppek K, Ludwig S (1999) Prävention des Chromat-Ekzems im Baugewerbe. Derm Beruf Umwelt 47:13–15 Struppek K, Ludwig S (1999) Prävention des Chromat-Ekzems im Baugewerbe. Derm Beruf Umwelt 47:13–15
go back to reference Thyssen JP, Jensen P, Carlsen BC, Engkilde K, Menné T, Johansen JD (2009) The prevalence of chromium allergy in Denmark is currently increasing as a result of leather exposure. Br J Dermatol 161:1288–1293CrossRef Thyssen JP, Jensen P, Carlsen BC, Engkilde K, Menné T, Johansen JD (2009) The prevalence of chromium allergy in Denmark is currently increasing as a result of leather exposure. Br J Dermatol 161:1288–1293CrossRef
go back to reference Uter W, Schnuch A, Geier J, Frosch PJ (1998) Epidemiology of contact dermatitis. The Information Network of Departments of Dermatology (IVDK) in Germany. Eur J Dermatol 8:36–40 Uter W, Schnuch A, Geier J, Frosch PJ (1998) Epidemiology of contact dermatitis. The Information Network of Departments of Dermatology (IVDK) in Germany. Eur J Dermatol 8:36–40
go back to reference Uter W, Rühl R, Pfahlberg A, Geier J, Schnuch A, Gefeller O (2004a) Contact allergy in construction workers: results of a multifactorial analysis. Ann Occup Hyg 48:21–27CrossRef Uter W, Rühl R, Pfahlberg A, Geier J, Schnuch A, Gefeller O (2004a) Contact allergy in construction workers: results of a multifactorial analysis. Ann Occup Hyg 48:21–27CrossRef
go back to reference Uter W, Schnuch A, Gefeller O (2004b) Guidelines for the descriptive presentation and statistical analysis of contact allergy data. Contact Dermat 51:47–56CrossRef Uter W, Schnuch A, Gefeller O (2004b) Guidelines for the descriptive presentation and statistical analysis of contact allergy data. Contact Dermat 51:47–56CrossRef
go back to reference Uter W, Mackiewicz M, Schnuch A, Geier J (2005) Interne Qualitätssicherung von Epikutantest-Daten des multizentrischen Projektes „Informationsverbund Dermatologischer Kliniken” (IVDK). Derm Beruf Umwelt 53:107–114 Uter W, Mackiewicz M, Schnuch A, Geier J (2005) Interne Qualitätssicherung von Epikutantest-Daten des multizentrischen Projektes „Informationsverbund Dermatologischer Kliniken” (IVDK). Derm Beruf Umwelt 53:107–114
go back to reference Uter W, Hegewald J, Pfahlberg A, Lessmann H, Schnuch A, Gefeller O (2010) Contact allergy to thiurams: multifactorial analysis of clinical surveillance data collected by the IVDK network. Int Arch Occup Environ Health, e-pub 31 Dec 2009 Uter W, Hegewald J, Pfahlberg A, Lessmann H, Schnuch A, Gefeller O (2010) Contact allergy to thiurams: multifactorial analysis of clinical surveillance data collected by the IVDK network. Int Arch Occup Environ Health, e-pub 31 Dec 2009
Metadata
Title
Occupational contact allergy in the building trade in Germany: influence of preventive measures and changing exposure
Authors
Johannes Geier
Andrea Krautheim
Wolfgang Uter
Holger Lessmann
Axel Schnuch
Publication date
01-04-2011
Publisher
Springer-Verlag
Published in
International Archives of Occupational and Environmental Health / Issue 4/2011
Print ISSN: 0340-0131
Electronic ISSN: 1432-1246
DOI
https://doi.org/10.1007/s00420-010-0581-8

Other articles of this Issue 4/2011

International Archives of Occupational and Environmental Health 4/2011 Go to the issue