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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-04-2021 | Edema | Retinal Disorders

Choroidal thickening in retinal vein occlusion patients with serous retinal detachment

Authors: Lulu Chen, Mingzhen Yuan, Lu Sun, Youxin Chen

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 4/2021

Abstract

Purpose

To evaluate choroid thickness and macular retinal metrics in treatment naïve retinal vein occlusion (RVO) patients with serous retinal detachment (SRD) before and after intravitreal anti-vascular endothelial cell growth factor (VEGF) injection and to elucidate the possible role of choroid in the development of SRD and the potential role of SRD as a prognostic parameter.

Methods

This is a retrospective study involving 85 RVO patients, 41 central retinal vein occlusion (CRVO), and 44 branch retinal vein occlusion (BRVO), with macular edema: 21 central retinal vein occlusion and 22 branch retinal vein occlusion with SRD and the rest without SRD. Patients were evaluated with ophthalmic examinations and swept-source optical coherence tomography (SS-OCT) both before and 4–6 weeks after intravitreal anti-VEGF treatment. Choroid thickness and retinal metrics were measured and compared between SRD and non-SRD groups within each RVO subtype.

Results

In both CRVO and BRVO patients, the mean central subfield foveal thickness (CSFT) and central subfoveal choroid thickness (CSCT) of the SRD groups were thicker than those in the non-SRD groups (p < 0.05) at onset. After one anti-VEGF injection, CSFT and FNRT decreased in all groups (p < 0.05). The CSCTs were thicker in the SRD groups compared with the non-SRD groups (p < 0.05). The mean changes of CSFT were more remarkable in the SRD groups (p < 0.05).

Conclusion

Thicker choroid was a feature of naïve RVO patients with SRD and SRD may be an indicator of better anatomical recovery of retina in RVO patients after a single dose of anti-VEGF treatment.

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Title: Choroidal thickening in retinal vein occlusion patients with serous retinal detachment
Authors: Lulu Chen
Mingzhen Yuan
Lu Sun
Youxin Chen
Publication date: 01-04-2021
Publisher: Springer Berlin Heidelberg
Keywords: Edema
Retinal Detachment
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 4/2021
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-020-04983-3

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Springer Medicine

Choroidal thickening in retinal vein occlusion patients with serous retinal detachment

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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