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Graefe's Archive for Clinical and Experimental Ophthalmology

Published in:

01-09-2018 | Retinal Disorders

Optical coherence tomography angiography in retinal vein occlusions

Authors: Qian Wang, Szy Yann Chan, Yanni Yan, Jingyan Yang, Wenjia Zhou, Jost B. Jonas, Wen Bin Wei

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 9/2018

Abstract

Purpose

To examine the vascular density in different retinal layers and in the choriocapillaris in eyes with retinal vein occlusions (RVO).

Methods

Applying optical coherence tomography angiography (OCTA), we examined patients with unilateral RVOs and normal individuals of a control group.

Results

The study group included 48 patients with unilateral RVO and the control group 17 normal individuals. Eyes affected by RVO as compared to the contralateral unaffected eyes (all P < 0.001), and the contralateral unaffected eyes as compared to the eyes of the control group (P < 0.05), showed a lower vessel density in the superficial and deep retinal layers in all regions except for the foveal region. Choriocapillaris density was lower (P < 0.001), foveal retinal thickness and subfoveal choroidal thickness (P < 0.001) were thicker, and the foveal avascular zone was larger (P = 0.003) in the RVO eyes than in the contralateral eyes. For 29 eyes undergoing OCTA and fluorescein angiography, two examiners independently rated the retinas to be ischemic in fluorescein angiography in 14 eyes and in OCTA in 9 of these 14 eyes.

Conclusions

Upon OCTA, unaffected eyes of patients with unilateral RVOs showed vascular abnormalities in the superficial and deep retinal layers when compared to those of healthy individuals.

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Title: Optical coherence tomography angiography in retinal vein occlusions
Authors: Qian Wang
Szy Yann Chan
Yanni Yan
Jingyan Yang
Wenjia Zhou
Jost B. Jonas
Wen Bin Wei
Publication date: 01-09-2018
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 9/2018
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-018-4038-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Optical coherence tomography angiography in retinal vein occlusions

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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